FI831049A0 - NYA CYCLOALKA / C / PYRROLKARBONSYRADERIVAT, FOERFARANDE FOER DERAS FRAMSTAELLNING, DESSA INNEHAOLLANDEAEMNEN OCH DERAS ANVAENDNING SAMT NYA CYKLOALKA / C / PYRROLKARBONSYROR FOSDER OOSOM MELLAN - Google Patents
NYA CYCLOALKA / C / PYRROLKARBONSYRADERIVAT, FOERFARANDE FOER DERAS FRAMSTAELLNING, DESSA INNEHAOLLANDEAEMNEN OCH DERAS ANVAENDNING SAMT NYA CYKLOALKA / C / PYRROLKARBONSYROR FOSDER OOSOM MELLANInfo
- Publication number
- FI831049A0 FI831049A0 FI831049A FI831049A FI831049A0 FI 831049 A0 FI831049 A0 FI 831049A0 FI 831049 A FI831049 A FI 831049A FI 831049 A FI831049 A FI 831049A FI 831049 A0 FI831049 A0 FI 831049A0
- Authority
- FI
- Finland
- Prior art keywords
- nya
- pyrrolkarbonsyror
- pyrrolkarbonsyraderivat
- oosom
- innehaollandeaemnen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19823211676 DE3211676A1 (en) | 1982-03-30 | 1982-03-30 | NEW DERIVATIVES OF CYCLOALKA (C) PYRROL CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, THEIR SUBSTANCES AND THE USE THEREOF AND NEW CYCLOALKA (C) PYRROL CARBONIC ACIDS AS THE INTERMEDIATE LEVELS AND METHODS |
Publications (2)
Publication Number | Publication Date |
---|---|
FI831049A0 true FI831049A0 (en) | 1983-03-28 |
FI831049L FI831049L (en) | 1983-10-01 |
Family
ID=6159702
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI831049A FI831049L (en) | 1982-03-30 | 1983-03-28 | NYA CYCLOALKA / C / PYRROLKARBONSYRADERIVAT, FOERFARANDE FOER DERAS FRAMSTAELLNING, DESSA INNEHAOLLANDEAEMNEN OCH DERAS ANVAENDNING SAMT NYA CYKLOALKA / C / PYRROLKARBONSYROR FOSDER OOSOM MELLAN |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0090362A3 (en) |
JP (1) | JPS58177967A (en) |
KR (1) | KR840004069A (en) |
AU (1) | AU560124B2 (en) |
CA (1) | CA1198118A (en) |
DE (1) | DE3211676A1 (en) |
DK (1) | DK144783A (en) |
ES (2) | ES8401937A1 (en) |
FI (1) | FI831049L (en) |
GR (1) | GR78157B (en) |
HU (1) | HU193876B (en) |
IL (1) | IL68267A (en) |
NO (2) | NO831168L (en) |
NZ (1) | NZ203719A (en) |
PH (1) | PH19003A (en) |
PT (1) | PT76472B (en) |
ZA (1) | ZA832229B (en) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3226768A1 (en) * | 1981-11-05 | 1983-05-26 | Hoechst Ag, 6230 Frankfurt | DERIVATIVES OF CIS, ENDO-2-AZABICYCLO- (3.3.0) -OCTAN-3-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THE USE THEREOF |
CA1341296C (en) * | 1981-12-29 | 2001-09-25 | Hansjorg Urbach | 2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use |
DE3246503A1 (en) * | 1982-12-16 | 1984-06-20 | Hoechst Ag, 6230 Frankfurt | DERIVATIVES OF CIS, ENDO-2-AZABICYCLO- (5.3.0) -DECAN-3-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THE USE THEREOF |
US5175306A (en) * | 1983-01-31 | 1992-12-29 | Hoechst Aktiengesellschaft | Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters |
DE3303344A1 (en) | 1983-02-02 | 1984-08-02 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED AMINO ACIDS AND THEIR ESTERS |
DK156484A (en) * | 1983-03-16 | 1984-09-17 | Usv Pharma Corp | AMINO ACID DERIVATIVES |
FR2546886B2 (en) * | 1983-06-06 | 1986-05-16 | Adir | DERIVATIVES OF ISOINDOLEDICARBOXYLIC ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
DE3333455A1 (en) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS |
DE3333454A1 (en) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS |
DE3410732A1 (en) * | 1984-03-23 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | METHOD FOR TREATING GLAUCOMA |
US5684016A (en) * | 1984-04-12 | 1997-11-04 | Hoechst Aktiengesellschaft | Method of treating cardiac insufficiency |
DE3413710A1 (en) * | 1984-04-12 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | METHOD FOR TREATING HEART INSUFFICIENCY |
WO1986000896A1 (en) * | 1984-07-30 | 1986-02-13 | Schering Corporation | NOVEL PROCESS FOR THE PREPARATION OF CIS, ENDOOCTAHYDROCYCLOPENTA ADb BDPYRROLE-2-CARBOXYLATE |
DE3431541A1 (en) * | 1984-08-28 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | CIS, ENDO-2-AZABICYCLOALKAN-3-CARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND INTERMEDIATE PRODUCTS IN THEIR PRODUCTION |
US5231080A (en) * | 1985-10-15 | 1993-07-27 | Hoechst Aktiengesellschaft | Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease |
US5231084A (en) * | 1986-03-27 | 1993-07-27 | Hoechst Aktiengesellschaft | Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons |
DE3633496A1 (en) * | 1986-10-02 | 1988-04-14 | Hoechst Ag | COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS WITH CALCIUMANTAGONISTS AND THEIR USE IN MEDICINAL PRODUCTS |
DE3639879A1 (en) * | 1986-11-21 | 1988-06-01 | Hoechst Ag | METHOD FOR PRODUCING MONO, BI AND TRICYCLIC AMINO ACIDS, INTERMEDIATE PRODUCTS OF THIS METHOD, AND A METHOD FOR PRODUCING THE SAME |
DE3722007A1 (en) * | 1987-07-03 | 1989-01-12 | Hoechst Ag | METHOD FOR PRODUCING BICYCLIC AMINOCARBONIC ACIDS, INTERMEDIATE PRODUCTS OF THIS METHOD AND THE USE THEREOF |
JPH0278659A (en) * | 1988-09-12 | 1990-03-19 | Shionogi & Co Ltd | Compound of azabicycloalkanes |
DE3839127A1 (en) * | 1988-11-19 | 1990-05-23 | Hoechst Ag | PYRROLIDONE-2-CARBONIC ACID DERIVATIVES WITH PSYCHOTROPER EFFECT |
DD284030A5 (en) | 1988-11-24 | 1990-10-31 | Hoechst Ag,De | PROCESS FOR THE PREPARATION OF PEPTIDES WITH BRADYKININ-ANTAGONISTIC EFFECT |
LT3872B (en) | 1993-12-06 | 1996-04-25 | Hoechst Ag | Novel peptides and pharmaceutical compositions containing them |
FR2746394B1 (en) | 1996-03-20 | 1998-05-29 | Roussel Uclaf | NOVEL TRICYCLIC COMPOUNDS, THEIR PREPARATION PROCESS, AND INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
DE59706273D1 (en) | 1996-03-20 | 2002-03-21 | Hoechst Ag | Bone resorption inhibitors and vitronectin receptor antagonists |
PL194025B1 (en) | 1996-10-18 | 2007-04-30 | Vertex Pharma | Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease |
DE19653647A1 (en) | 1996-12-20 | 1998-06-25 | Hoechst Ag | Vitronectin receptor antagonists, their preparation and their use |
DE19741235A1 (en) | 1997-09-18 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Novel imidazolidine derivatives, their preparation, their use and pharmaceutical compositions containing them |
DE19741873A1 (en) * | 1997-09-23 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | New 5-ring heterocycles, their preparation, their use and pharmaceutical preparations containing them |
DE19751251A1 (en) | 1997-11-19 | 1999-05-20 | Hoechst Marion Roussel De Gmbh | Substituted imidazolidine derivatives, their manufacture, their use and pharmaceutical preparations containing them |
DE19821483A1 (en) | 1998-05-14 | 1999-11-18 | Hoechst Marion Roussel De Gmbh | New imidazolidine derivatives useful as leukocyte adhesion and migration inhibitors and/or VLA-4 receptor antagonists for treating E.G. inflammatory and allergic disorders |
SV2003000617A (en) | 2000-08-31 | 2003-01-13 | Lilly Co Eli | INHIBITORS OF PROTEASA PEPTIDOMIMETICA REF. X-14912M |
PE20050374A1 (en) | 2003-09-05 | 2005-05-30 | Vertex Pharma | SERINE PROTEASE INHIBITORS, IN PARTICULAR HCV PROTEASE NS3-NS4A |
US8399615B2 (en) | 2005-08-19 | 2013-03-19 | Vertex Pharmaceuticals Incorporated | Processes and intermediates |
NZ566049A (en) | 2005-08-19 | 2011-07-29 | Vertex Pharma | Processes and intermediates |
AR055395A1 (en) | 2005-08-26 | 2007-08-22 | Vertex Pharma | INHIBITING COMPOUNDS OF THE ACTIVITY OF SERINA PROTEASA NS3-NS4A OF HEPATITIS C VIRUS |
US7964624B1 (en) | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
AU2007217355B2 (en) | 2006-02-27 | 2012-06-21 | Vertex Pharmaceuticals Incorporated | Co-crystals comprising VX-950 and pharmaceutical compositions comprising the same |
MX2008011868A (en) | 2006-03-16 | 2008-12-15 | Vertex Pharma | Deuterated hepatitis c protease inhibitors. |
US8575208B2 (en) | 2007-02-27 | 2013-11-05 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
ES2379905T3 (en) | 2007-02-27 | 2012-05-04 | Vertex Pharmceuticals Incorporated | Co-crystals and pharmaceutical compositions comprising them |
NZ583699A (en) | 2007-08-30 | 2012-04-27 | Vertex Pharma | Co-crystals of vx-950 (telaprevir) other components and pharmaceutical compositions comprising the same |
US8178333B2 (en) | 2008-06-24 | 2012-05-15 | Codexis, Inc. | Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds |
JP5829529B2 (en) * | 2011-08-29 | 2015-12-09 | 日本曹達株式会社 | Optically active quaternary ammonium salt and method for producing optically active compound |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
FR2487829A2 (en) * | 1979-12-07 | 1982-02-05 | Science Union & Cie | NOVEL SUBSTITUTED IMINO ACIDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS AN ENZYME INHIBITOR |
DE3174844D1 (en) * | 1980-10-23 | 1986-07-24 | Schering Corp | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them |
DE3260423D1 (en) * | 1981-02-17 | 1984-08-30 | Warner Lambert Co | Substituted acyl derivatives of octahydro-1h-isoindole-1-carboxylic acids and esters |
ZA826022B (en) * | 1981-08-21 | 1983-08-31 | Univ Miami | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides |
EP0081094A1 (en) * | 1981-11-12 | 1983-06-15 | Merck & Co. Inc. | Substituted omega-amino-carboxymethyldipeptide antihypertensive agents |
DE3360065D1 (en) * | 1982-03-08 | 1985-03-28 | Schering Corp | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them |
-
1982
- 1982-03-30 DE DE19823211676 patent/DE3211676A1/en not_active Withdrawn
-
1983
- 1983-03-24 EP EP83102961A patent/EP0090362A3/en not_active Withdrawn
- 1983-03-28 GR GR70912A patent/GR78157B/el unknown
- 1983-03-28 ES ES521041A patent/ES8401937A1/en not_active Expired
- 1983-03-28 FI FI831049A patent/FI831049L/en not_active Application Discontinuation
- 1983-03-28 NZ NZ203719A patent/NZ203719A/en unknown
- 1983-03-28 KR KR1019830001244A patent/KR840004069A/en not_active Application Discontinuation
- 1983-03-29 PT PT76472A patent/PT76472B/en unknown
- 1983-03-29 HU HU831064A patent/HU193876B/en unknown
- 1983-03-29 CA CA000424770A patent/CA1198118A/en not_active Expired
- 1983-03-29 PH PH28723A patent/PH19003A/en unknown
- 1983-03-29 DK DK144783A patent/DK144783A/en not_active Application Discontinuation
- 1983-03-29 JP JP58051780A patent/JPS58177967A/en active Pending
- 1983-03-29 NO NO831168A patent/NO831168L/en unknown
- 1983-03-29 AU AU12970/83A patent/AU560124B2/en not_active Ceased
- 1983-03-29 ZA ZA832229A patent/ZA832229B/en unknown
- 1983-03-30 IL IL68267A patent/IL68267A/en unknown
- 1983-04-22 ES ES521741A patent/ES521741A0/en active Granted
- 1983-11-25 NO NO834352A patent/NO834352L/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES8402570A1 (en) | 1984-02-01 |
NO834352L (en) | 1983-10-03 |
PT76472B (en) | 1986-01-24 |
IL68267A0 (en) | 1983-06-15 |
ES521041A0 (en) | 1984-01-01 |
ES521741A0 (en) | 1984-02-01 |
PH19003A (en) | 1985-12-03 |
ES8401937A1 (en) | 1984-01-01 |
FI831049L (en) | 1983-10-01 |
HU193876B (en) | 1987-12-28 |
AU560124B2 (en) | 1987-04-02 |
EP0090362A2 (en) | 1983-10-05 |
DK144783A (en) | 1983-10-01 |
DE3211676A1 (en) | 1983-10-06 |
PT76472A (en) | 1983-04-01 |
JPS58177967A (en) | 1983-10-18 |
NO831168L (en) | 1983-10-03 |
ZA832229B (en) | 1983-12-28 |
GR78157B (en) | 1984-09-26 |
DK144783D0 (en) | 1983-03-29 |
AU1297083A (en) | 1983-10-06 |
IL68267A (en) | 1987-03-31 |
NZ203719A (en) | 1986-02-21 |
KR840004069A (en) | 1984-10-06 |
EP0090362A3 (en) | 1985-09-18 |
CA1198118A (en) | 1985-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: HOECHST AKTIENGESELLSCHAFT |