FI810759L - SOM HJAERTMEDICIN ANVAENDBARA PYRAZOLOPYRIDINDERIVAT OCH DERAS FRAMSTAELLNINGSFOERFARANDE - Google Patents

SOM HJAERTMEDICIN ANVAENDBARA PYRAZOLOPYRIDINDERIVAT OCH DERAS FRAMSTAELLNINGSFOERFARANDE

Info

Publication number
FI810759L
FI810759L FI810759A FI810759A FI810759L FI 810759 L FI810759 L FI 810759L FI 810759 A FI810759 A FI 810759A FI 810759 A FI810759 A FI 810759A FI 810759 L FI810759 L FI 810759L
Authority
FI
Finland
Prior art keywords
pyrazolopyridinderivat
hjaertmedicin
anvaendbara
som
och deras
Prior art date
Application number
FI810759A
Other languages
Finnish (fi)
Inventor
George Yohe Lesher
Monte D Gruett
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FI810759L publication Critical patent/FI810759L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI810759A 1980-03-17 1981-03-11 SOM HJAERTMEDICIN ANVAENDBARA PYRAZOLOPYRIDINDERIVAT OCH DERAS FRAMSTAELLNINGSFOERFARANDE FI810759L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/131,227 US4264603A (en) 1980-03-17 1980-03-17 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridine-3-amines, their use as cardiotonics and their preparation

Publications (1)

Publication Number Publication Date
FI810759L true FI810759L (en) 1981-09-18

Family

ID=22448499

Family Applications (1)

Application Number Title Priority Date Filing Date
FI810759A FI810759L (en) 1980-03-17 1981-03-11 SOM HJAERTMEDICIN ANVAENDBARA PYRAZOLOPYRIDINDERIVAT OCH DERAS FRAMSTAELLNINGSFOERFARANDE

Country Status (19)

Country Link
US (1) US4264603A (en)
JP (1) JPS56142281A (en)
KR (1) KR830005214A (en)
AU (1) AU6826081A (en)
BE (1) BE887890A (en)
DE (1) DE3109768A1 (en)
DK (1) DK114381A (en)
ES (1) ES8202339A1 (en)
FI (1) FI810759L (en)
FR (1) FR2478100A1 (en)
GB (1) GB2071660A (en)
IL (1) IL62295A0 (en)
IT (1) IT1141998B (en)
LU (1) LU83214A1 (en)
NL (1) NL8101217A (en)
NO (1) NO810834L (en)
PT (1) PT72654B (en)
SE (1) SE8101591L (en)
ZA (1) ZA811418B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361568A (en) * 1981-04-28 1982-11-30 Sterling Drug Inc. 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-amines and their cardiotonic use
US4374141A (en) * 1981-08-17 1983-02-15 Sterling Drug Inc. 2-Substituted amino-5-(pyridinyl)-nicotinamides and their cardiotonic use
EP0200024B1 (en) 1985-04-30 1992-07-01 ARZNEIMITTELWERK DRESDEN GmbH 3-cyano-pyridines, process for their preparation and their pharmaceutical use
DD298781A5 (en) * 1990-03-09 1992-03-12 Inst Wirkstofforschung PROCESS FOR THE PREPARATION OF 5,4'-BIPYRIDINE-1'-OXIDES
JP4814783B2 (en) * 2003-02-27 2011-11-16 パラウ ファルマ、 ソシエダッド アノニマ Pyrazolopyridine derivative
US20090008238A1 (en) * 2004-04-09 2009-01-08 The Arizona Bd Of Reg On Behalf Of The Univ Of Az Transportable gas sterilization unit, disposable gas generator, light activated anti-infective coating and method of disinfection and sterilization using chlorine dioxide
AR050188A1 (en) * 2004-08-03 2006-10-04 Uriach Y Compania S A J CONDENSED HETEROCICLIC COMPOUNDS USED IN THERAPY AS INHIBITORS OF P38 KINASES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CN102558044A (en) * 2011-12-29 2012-07-11 方晏燕 Method for crystallizing milrinone
CN103664773A (en) * 2013-12-18 2014-03-26 南京易亨制药有限公司 Preparing method and refining method for milrinone

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423414A (en) * 1966-01-13 1969-01-21 Ciba Geigy Corp Pyrazolopyridines
DE2160780A1 (en) * 1971-12-08 1973-06-14 Basf Ag Pyridine pyrazoles - prepd from 5-cyano-6-chloro-pyridine derivs and hydrazines, used as diazo components
DE2232038A1 (en) * 1972-06-30 1974-01-10 Hoechst Ag 3-AMINO-1H-PYRAZOLO SQUARE CLAMP ON 3.4-ANGLE BRACKET FOR PYRIDINE, THEIR PRODUCTION AND USE
US4004012A (en) * 1975-10-14 1977-01-18 Sterling Drug Inc. 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) * 1975-10-14 1978-02-07 Sterling Drug Inc. 3-Amino-5-(pyridinyl)-2(1H)-pyridinones
US4020072A (en) * 1976-05-04 1977-04-26 E. R. Squibb & Sons, Inc. 5-Aminomethyl-1H-pyrazolo[3,4-b]pyridines

Also Published As

Publication number Publication date
BE887890A (en) 1981-09-11
DK114381A (en) 1981-09-18
ES500412A0 (en) 1982-01-16
ES8202339A1 (en) 1982-01-16
IL62295A0 (en) 1981-05-20
JPS56142281A (en) 1981-11-06
GB2071660A (en) 1981-09-23
SE8101591L (en) 1981-09-18
ZA811418B (en) 1982-03-31
IT8120271A0 (en) 1981-03-10
AU6826081A (en) 1981-09-24
PT72654B (en) 1982-03-19
PT72654A (en) 1981-04-01
IT1141998B (en) 1986-10-08
FR2478100A1 (en) 1981-09-18
LU83214A1 (en) 1981-10-30
NL8101217A (en) 1981-10-16
US4264603A (en) 1981-04-28
KR830005214A (en) 1983-08-03
DE3109768A1 (en) 1981-12-24
NO810834L (en) 1981-09-18

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Owner name: STERLING DRUG INC