FI57613C - DETERGENTSTAENGER - Google Patents

Description

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Patent and Registration Office · (44) Date of issue of the publication. -

Patent- och regittarstyralMn AnaMcan Utlagd och utUkrMtm publfcerad 30,05.80 (32) (33) (31) requested • tuolkeu * —B «* ird prlorlttt 28.01.72

England-England (GB) Ul80 / 72 Tot shown-Styrkt (71) Unilever N.V., Burgemeester s'Jacobplein 1, Rotterdam, Holland-Holland (NL) (72) Gordon Francis Johnston, Ellesmere Port, Cheshire, Alexander Martin,

Warrington, Lancashire, Alan Digby Tomlinson, Neston, Cheshire, England-England (GB) (7¾) Leitzinger 0y (5¾) Detergent Sticks This invention relates to a detergent bar for personal washing which contains a detergent active ingredient and an additive.

By adding a moisturizing component to the topical solution, it is known to increase the retention of water on the skin. This component increases the water retention of the skin.

The detergent bar according to the invention is characterized in that it contains, as an additive, 20 to 55% by weight of a water-soluble lactate salt, or a mixture of 20 to 55% by weight of a water-soluble salt of glutamic acid and a water-soluble lactate salt, wherein the lactate is at least 10% by weight. 80% by weight of a detergent, and that the additive is one which increases the water content of the skin.

Water-soluble salts are usually alkali metal salts, for example sodium, potassium salts or alkanolamine or ammonium salts.

It has been found that these components can be incorporated into detergent bars having useful physical properties. Ts. for example, softness, extrudability, and wear are sufficient for an acceptable rod. Applicants have further found that 2 57613 of these moisturizing components act on the skin in a rinsing situation, i. in a situation where a wash bar is used to wash the skin and the wash liquid is rinsed relatively soon after the wash step.

The detergent bars according to the invention preferably contain at least 20% by weight of lactate salt and at least 10% by weight of glutamate salt.

In order to have a satisfactory effect on the skin during use, the amount of moisturizing component or components must be at least 20%. The purpose of the glutamic acid salts involved is to give the rod bar properties for processing in addition to giving it wetting properties. The presence of glutamates is preferred when the lactate is greater than about 20% of the rod. Thus, the rod may contain 10% of each component or 20% of lactate as alternative combinations of substances. Lactate and glutamate salts may contain free acid depending on the pH of the detergent. The term water-soluble salt as used herein includes any free acid present.

Examples of detergent active ingredients used to form the detergent bar of the invention are in the following categories (other active ingredients are disclosed in Schwarz & Perry, Surface Active Agents, Interscience 1949, and Schwartz, Perry & Berch, ibid, Volume II, Interscience, (1958): (a) isethionates containing an alkyl group of 8 to 18 carbon atoms, such as the active substances designated "Igepon A", which can be obtained, for example, from coconut fatty acids, (b) alkali metal salts of alkanesulfonates having an alkyl chain length of 11 to 14. the substances are prepared by reaction with a bisulfite ion with an olefin; (c) sulfates of branched chain alcohols having a chain length of 12 to 15. These alcohols are obtained under the tradename "Dobanol"; (d) alkylarylsulfonates having an alkyl chain of C10-C15-153513 ( (e) dialkali metal salts of sulphonated saturated fatty acids with a chain length of C12 to C20; (f) ethoxylated alcohols ( C2-2 to C2q) having an degree of ethylation between 10 and 20; (g) alkyl (C 2 -C 10 C) sulfates having a degree of branching at the alpha position of up to 25%; (h) alkene sulfonates having a chain length of -C 1; (i) alkali metal salts of Cg to C22 long chain fatty acids; and (j) nonionic detergents, for example alcohols, polyoxyalkylene derivatives, alkylamides and alkanolamides, polyoxyalkylene esters of acids, alkylene oxide block polymers (e.g. Pluronics), polyol esters and acylalkanolamides.

Other examples of active substances are amphoteric substances, betaines and cationic substances, e.g. ethoxylated quaternary compounds.

The rods may contain other substances, for example water, usually up to 20%, pH adjusters, germicides, perfumes and plasticizers.

The detergent bars according to the invention may also contain other components which moisturize the skin during washing, for example 2-pyrrolidone-5-carboxylic acid and its salts, hydrolysed proteins and salts of N-acetylglycine.

Mixtures of detergent agents may be used, for example (i) a mixture of alkanesulphonates and alkenesulphonates as described in British Patent 1,171,616 and (ii) a mixture of fatty alcohol 18 E0 and Igepon A.

The wetting component can be added at any stage of the rod treatment, provided that the component is not subjected to degrading * 5761 3 treatment steps. The components can be added as the free acid or salt depending on the pH of the detergent used, i.e. when the active substance is very alkaline, the free acid can be added to form a salt in the rod.

The following are examples of washing rods according to the invention.

In the next test, a damaged guinea pig stratum corneum was used. The test method was as follows.

The hind legs of the guinea pigs are removed with a scalpel and incubated in buffered trypsin solution (pH 7.2) at UO ° C overnight. The remaining stratum corneum is washed in distilled water for 4 hours. Damage (decreased water binding capacity) is caused by soaking the stratum corneum in ether overnight and then washing in distilled water for 6 hours. The stratum corneum can then be used.

Pieces of stratum corneum are soaked in 10% solutions of surfactant + wetting agent or agents for periods lasting up to 30 minutes. Then rinse with distilled water for 5 minutes. The stratum corneum is patted dry and hung for 6 days to equilibrate in air at 90% relative humidity. The stratum corneum is weighed and further equilibrated for 6 days in dry air before reweighing.

Calculate the water-binding capacity and express it as the amount of water retained by 100 mg of dry stratum corneum.

Test rods containing mixtures of detergent and wetting components were formed by mixing the materials in the first step. All rods produced had acceptable physical properties. The results are expressed as the amount of water (mg) retained by 100 mg of dry stratum corneum.

The rods were also tested for hand washing and were found to wet hands. Both components vds / at are in D or L forms, but the present invention does not depend on the optical isomer (s) used. The lactate used in the following examples was a mixture of both forms, and the glutamate was Form D.

5761 3

Example 1 Using sodium coconut thionate, a series of four bars were prepared containing 10, 20 and 50% by weight of a 50:50 mixture of monosodium glutamate and lactate. The amounts of water bound were:

No wetting agent 27.11

Wetting agent 20% 31.72 "30% 31 +, 814" 50% 41.38

Example 2

A series of test rods were prepared using the active ingredients and wetting components shown in Table I. The properties of the rods were satisfactory. The results in the table illustrate the wetting property. Water binding capacity was measured using the test described previously. Alcohol 14 is a specific alcohol.

.Seös A Sodium coconut thionate 54%

Stearic acid 25%

Sodium fatty soap 9%

Sodium cetionate 7%

Sodium dodecylbenzenesulphonate 3%

Mixture B Sodium coconut thionate 78% C ^ q - C ^ g fatty acids 28%

Example 3 Using sodium coconut thionate as a detergent, a rod containing a 50:50 mixture of 50% sodium 2-pyrrolidone-5-carboxylate and sodium lactate was prepared. The amounts of water bound were

No wetting agent - 27.11

Test rod - 39.50

Example 4 6 5761 3

A series of pine soap bars containing 20, 30, 40 and 50% lactate were prepared. The presence of lactate was found to increase the wetting properties of the soap when used in a hand washing experiment.

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