FI56018B - REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDER - Google Patents

REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDER

Info

Publication number
FI56018B
FI56018B FI333/71A FI33371A FI56018B FI 56018 B FI56018 B FI 56018B FI 333/71 A FI333/71 A FI 333/71A FI 33371 A FI33371 A FI 33371A FI 56018 B FI56018 B FI 56018B
Authority
FI
Finland
Prior art keywords
azapyrimidinnucleosider
framstaellning
Prior art date
Application number
FI333/71A
Other languages
Finnish (fi)
Other versions
FI56018C (en
Inventor
Helmut Vorbrueggen
Ulrich Niedballa
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of FI56018B publication Critical patent/FI56018B/en
Publication of FI56018C publication Critical patent/FI56018C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI333/71A 1970-03-14 1971-02-08 REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDER FI56018C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2012888A DE2012888C3 (en) 1970-03-14 1970-03-14 Process for the preparation of 5-azapyrimidine nucleosides

Publications (2)

Publication Number Publication Date
FI56018B true FI56018B (en) 1979-07-31
FI56018C FI56018C (en) 1979-11-12

Family

ID=5765475

Family Applications (1)

Application Number Title Priority Date Filing Date
FI333/71A FI56018C (en) 1970-03-14 1971-02-08 REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDER

Country Status (19)

Country Link
US (1) US3817980A (en)
JP (1) JPS5527077B1 (en)
AT (1) AT313481B (en)
BE (1) BE764179A (en)
CA (1) CA946379A (en)
CH (1) CH552606A (en)
CS (1) CS162741B2 (en)
DE (1) DE2012888C3 (en)
DK (1) DK152134C (en)
ES (1) ES388193A1 (en)
FI (1) FI56018C (en)
FR (1) FR2085707B1 (en)
GB (1) GB1351003A (en)
HU (1) HU164144B (en)
IL (1) IL36363A (en)
NL (1) NL180835C (en)
PL (1) PL81543B1 (en)
SE (1) SE405253B (en)
ZA (1) ZA711084B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1531469A (en) * 1975-12-18 1978-11-08 Farmaceutici Italia Daunosamine nucleosides
US4171431A (en) * 1976-08-19 1979-10-16 The Upjohn Company Nucleosides and process
DE2721466A1 (en) * 1977-05-12 1978-11-16 Robugen Gmbh PROCESS FOR THE PREPARATION OF 2'-DESOXYRIBOFURANOSYL NUCLEOSIDES
DE2757365A1 (en) * 1977-12-20 1979-06-21 Schering Ag NEW PROCESS FOR THE PRODUCTION OF NUCLEOSIDES
GB1601020A (en) 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
US4423212A (en) * 1980-12-18 1983-12-27 The Upjohn Company Nucleosides and process
US5099010A (en) * 1983-01-17 1992-03-24 Research Corporation Intermediates in the preparation of 3'-amino-2',3'-dideoxycytidine and the pharmacologically acceptable salts thereof
JPS60193997A (en) * 1984-03-14 1985-10-02 Sumitomo Chem Co Ltd New cyanoimidazole ribonucleoside derivative and its preparation
US4730512A (en) * 1984-10-23 1988-03-15 Toyota Jidosha Kabushiki Kaisha Engine crankshaft structure
CA1301166C (en) * 1987-07-21 1992-05-19 John Nicholas Freskos Process for preparing 2-deoxynucleosides
US6982253B2 (en) * 2002-06-05 2006-01-03 Supergen, Inc. Liquid formulation of decitabine and use of the same
WO2004028454A2 (en) * 2002-09-24 2004-04-08 Koronis Pharmaceuticals, Incorporated 1, 3, 5-triazines for treatment of viral diseases
US7038038B2 (en) 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
AU2012209018B2 (en) * 2003-03-17 2015-04-02 Celgene International Sarl Methods for isolating crystalline Form I of 5-azacytidine
US6943249B2 (en) * 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
AU2013200662B2 (en) * 2003-03-17 2015-04-02 Celgene International Sarl Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) * 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US20060014949A1 (en) * 2004-07-13 2006-01-19 Supergen Inc. Compositions and formulations of decitabine polymorphs and methods of use thereof
US20060128654A1 (en) * 2004-12-10 2006-06-15 Chunlin Tang Pharmaceutical formulation of cytidine analogs and derivatives
US20060128653A1 (en) * 2004-12-10 2006-06-15 Chunlin Tang Pharmaceutical formulation of decitabine
EP2205073A4 (en) * 2007-09-26 2013-03-06 Sinai School Medicine Azacytidine analogues and uses thereof
EP2050757A1 (en) * 2007-10-10 2009-04-22 Cilag AG Method of producing 2' -deoxy-5-azacytidine (Decitabine)
EP2048151A1 (en) * 2007-10-10 2009-04-15 Cilag AG Method for producing nucleosides by direct glycosylation of the nucleoside base
PT3782612T (en) 2008-05-15 2024-01-18 Celgene Corp Oral formulations of cytidine analogs and methods of use thereof
WO2010014883A2 (en) 2008-08-01 2010-02-04 Dr. Reddy's Laboratories Ltd. Azacitidine process and polymorphs
KR20110026019A (en) 2008-08-06 2011-03-14 시코르, 인크. Process for preparing azacytidine intermediate
AU2009279461B2 (en) 2008-08-08 2014-01-23 Scinopharm Taiwan, Ltd. Process for making 5-azacytosine nucleosides and their derivatives
ES2681529T3 (en) * 2009-03-23 2018-09-13 Ambit Biosciences Corporation Treatment methods using combination therapy
US20100249394A1 (en) * 2009-03-26 2010-09-30 Albemarle Corporation Processes for producing decitabine
IT1399195B1 (en) 2010-03-30 2013-04-11 Chemi Spa PROCESS FOR THE SYNTHESIS OF AZACITIDINE AND DECITABINE
MX2013010945A (en) 2011-03-31 2014-03-12 Celgene Internat Sarl Systhesis of 5-azacytidine.
RS57449B1 (en) 2012-04-04 2018-09-28 Halozyme Inc Combination therapy with hyaluronidase and a tumor-targeted taxane
CN103884809B (en) * 2013-08-28 2016-01-27 鲁南制药集团股份有限公司 A kind of analyzing detecting method of Decitabine intermediate
JP6162349B1 (en) * 2016-04-21 2017-07-12 大原薬品工業株式会社 Sacyl moiety silyl ether derivatives of 5-azacytidines
CN108226309B (en) 2016-12-13 2020-06-16 江苏奥赛康药业有限公司 Analysis method of dexrazoxane
CN108239128B (en) 2016-12-23 2019-03-29 江苏奥赛康药业股份有限公司 The preparation method of beta-nucleosides class compound
CN110128485B (en) * 2018-02-09 2022-06-07 鲁南制药集团股份有限公司 Preparation method of azacitidine
US20190351031A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1244790B (en) * 1963-10-29 1967-07-20 Ceskoslovenska Akademie Ved Process for the production of the cancerostatically effective 5-azacytidine
GB1050899A (en) * 1963-12-22
US3328388A (en) * 1964-09-02 1967-06-27 Merck & Co Inc Arabinofuranosyl pyrimidines and methods of preparing same
US3346561A (en) * 1965-10-24 1967-10-10 Merck & Co Inc Pyrimidine 3-deoxynucleosides
US3531464A (en) * 1966-10-21 1970-09-29 Us Health Education & Welfare Alternative synthesis of 2'-deoxy-5-(trifluoromethyl)-uridine and the alphaanomer thereof
CH527207A (en) * 1968-05-08 1972-08-31 Ceskoslovenska Akademie Ved Process for the preparation of 1-glycosyl-5-azacytosines
CH507969A (en) * 1968-11-12 1971-05-31 Ceskoslovenska Akademie Ved Process for the preparation of 1-glycosyl-5-azacytosines
CH532062A (en) * 1968-11-13 1972-12-31 Ceskoslovenska Akademie Ved Process for the preparation of 1-glycosyl-5-azacytosines

Also Published As

Publication number Publication date
SU374828A3 (en) 1973-03-20
FR2085707B1 (en) 1975-04-18
FI56018C (en) 1979-11-12
AT313481B (en) 1974-02-25
PL81543B1 (en) 1975-08-30
DE2012888A1 (en) 1971-09-30
ES388193A1 (en) 1973-05-01
CA946379A (en) 1974-04-30
SE405253B (en) 1978-11-27
BE764179A (en) 1971-09-13
DE2012888B2 (en) 1980-07-10
CH552606A (en) 1974-08-15
JPS5527077B1 (en) 1980-07-17
IL36363A (en) 1974-05-16
NL180835B (en) 1986-12-01
HU164144B (en) 1973-12-28
FR2085707A1 (en) 1971-12-31
GB1351003A (en) 1974-04-24
DE2012888C3 (en) 1981-04-02
NL7103459A (en) 1971-09-16
DK152134B (en) 1988-02-01
US3817980A (en) 1974-06-18
CS162741B2 (en) 1975-07-15
IL36363A0 (en) 1971-05-26
ZA711084B (en) 1971-10-27
DK152134C (en) 1988-08-01
NL180835C (en) 1987-05-04

Similar Documents

Publication Publication Date Title
FI56018C (en) REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDER
FI55856B (en) FOERFARANDE FOER POLYMERISERING AV ETYLEN
FI53440C (en) REFERENCE TO A COVER BEHINDLING AV EN TEXTILTRAOD I EN KONTINUERLIGT ARBETANDE TRAODBEHANDLINGSMASKIN
FI56400B (en) FOERFARANDE FOER AVSKILJNING AV KVICKSILVER FRAON KVICKSILVERHALTIGA VAETSKEFASER
FI54057B (en) FOERFARANDE FOER FRAMSTAELLNING AV EN SKUMDAEMPARKOMPOSITION
FI54950C (en) FOERFARANDE FOER AVLAEGSNANDE AV ILLALUKTANDE SVAVELHALTIGA FOERENINGAR FRAON EN GASSTROEM
FI54345B (en) FOERFARANDE FOER FRAMSTAELLNING AV CELLULOSAMASSA
FI54139B (en) FOERFARANDE FOER KATALYTISK KRACKNING AV BENSIN
FI54032C (en) NORMERINGSFOERFARANDE FOER MAETNINGSANORDNING FOER BESTAEMNING AV KVADRAT METERVIKT
IT968027B (en) IMPROVEMENTS RELATING TO DENTALS
BR7100639D0 (en) IMPROVEMENTS RELATING TO BANKS
FI53903B (en) KOPPLINGSPLINT FOER SKRUVFRI ANSLUTNING AV ISOLERADE LEDARE
FI54482B (en) FOERFARANDE FOER FRAMSTAELLNING AV BRONKOLYTISKT AKTIVA TEOFYLLINDERIVAT
FI53521C (en) ROEKDETEKTOR FOER OPTISK DETEKTERING AV FOERBRAENNINGSALSTRADE AEROSOLER
BR7107958D0 (en) IMPROVEMENTS RELATING TO ANTICONCEPTIONAL DEVICES
FI53451C (en) REFERENCE TO A FRAMSTAELLNING AV (+ -) - 4-HYDROXIFENYLGLYCIN
BE772086R (en) CASE A
FI53839C (en) FOERFARANDE FOER KALKNING AV DJURSKINN ELLER -HUDAR
FI54350C (en) FOERFARANDE FOER OXIDERING AV SVARTLUT
IT944113B (en) OMERELLO TO LOSE
FI53304C (en) FOERFARANDE FOER FRAMSTAELLNING AV DES-FENYLALANIN B1-INSULIN
FI53450C (en) FOERFARANDE FOER FRAMSTAELLNING AV OPTISKT AKTIVA BICYKLISKA FOERENINGAR
FI54405C (en) ANLAEGGNING FOER KYLNING AV AONGA
FI53842C (en) FOERFARANDE FOER FRAMSTAELLNING AV FIBERPRODUKTER
FI54922B (en) NYTT FOERFARANDE FOER FRAMSTAELLNING AV PIPERAZINDERIVAT