FI56018B - REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDER - Google Patents
REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDERInfo
- Publication number
- FI56018B FI56018B FI333/71A FI33371A FI56018B FI 56018 B FI56018 B FI 56018B FI 333/71 A FI333/71 A FI 333/71A FI 33371 A FI33371 A FI 33371A FI 56018 B FI56018 B FI 56018B
- Authority
- FI
- Finland
- Prior art keywords
- azapyrimidinnucleosider
- framstaellning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2012888A DE2012888C3 (en) | 1970-03-14 | 1970-03-14 | Process for the preparation of 5-azapyrimidine nucleosides |
Publications (2)
Publication Number | Publication Date |
---|---|
FI56018B true FI56018B (en) | 1979-07-31 |
FI56018C FI56018C (en) | 1979-11-12 |
Family
ID=5765475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI333/71A FI56018C (en) | 1970-03-14 | 1971-02-08 | REFERENCE TO A FRAMSTAELLNING AV 5-AZAPYRIMIDINNUCLEOSIDER |
Country Status (19)
Country | Link |
---|---|
US (1) | US3817980A (en) |
JP (1) | JPS5527077B1 (en) |
AT (1) | AT313481B (en) |
BE (1) | BE764179A (en) |
CA (1) | CA946379A (en) |
CH (1) | CH552606A (en) |
CS (1) | CS162741B2 (en) |
DE (1) | DE2012888C3 (en) |
DK (1) | DK152134C (en) |
ES (1) | ES388193A1 (en) |
FI (1) | FI56018C (en) |
FR (1) | FR2085707B1 (en) |
GB (1) | GB1351003A (en) |
HU (1) | HU164144B (en) |
IL (1) | IL36363A (en) |
NL (1) | NL180835C (en) |
PL (1) | PL81543B1 (en) |
SE (1) | SE405253B (en) |
ZA (1) | ZA711084B (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1531469A (en) * | 1975-12-18 | 1978-11-08 | Farmaceutici Italia | Daunosamine nucleosides |
US4171431A (en) * | 1976-08-19 | 1979-10-16 | The Upjohn Company | Nucleosides and process |
DE2721466A1 (en) * | 1977-05-12 | 1978-11-16 | Robugen Gmbh | PROCESS FOR THE PREPARATION OF 2'-DESOXYRIBOFURANOSYL NUCLEOSIDES |
DE2757365A1 (en) * | 1977-12-20 | 1979-06-21 | Schering Ag | NEW PROCESS FOR THE PRODUCTION OF NUCLEOSIDES |
GB1601020A (en) | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
US4423212A (en) * | 1980-12-18 | 1983-12-27 | The Upjohn Company | Nucleosides and process |
US5099010A (en) * | 1983-01-17 | 1992-03-24 | Research Corporation | Intermediates in the preparation of 3'-amino-2',3'-dideoxycytidine and the pharmacologically acceptable salts thereof |
JPS60193997A (en) * | 1984-03-14 | 1985-10-02 | Sumitomo Chem Co Ltd | New cyanoimidazole ribonucleoside derivative and its preparation |
US4730512A (en) * | 1984-10-23 | 1988-03-15 | Toyota Jidosha Kabushiki Kaisha | Engine crankshaft structure |
CA1301166C (en) * | 1987-07-21 | 1992-05-19 | John Nicholas Freskos | Process for preparing 2-deoxynucleosides |
US6982253B2 (en) * | 2002-06-05 | 2006-01-03 | Supergen, Inc. | Liquid formulation of decitabine and use of the same |
WO2004028454A2 (en) * | 2002-09-24 | 2004-04-08 | Koronis Pharmaceuticals, Incorporated | 1, 3, 5-triazines for treatment of viral diseases |
US7038038B2 (en) | 2003-03-17 | 2006-05-02 | Pharmion Corporation | Synthesis of 5-azacytidine |
AU2012209018B2 (en) * | 2003-03-17 | 2015-04-02 | Celgene International Sarl | Methods for isolating crystalline Form I of 5-azacytidine |
US6943249B2 (en) * | 2003-03-17 | 2005-09-13 | Ash Stevens, Inc. | Methods for isolating crystalline Form I of 5-azacytidine |
AU2013200662B2 (en) * | 2003-03-17 | 2015-04-02 | Celgene International Sarl | Methods for isolating crystalline Form I of 5-azacytidine |
US6887855B2 (en) * | 2003-03-17 | 2005-05-03 | Pharmion Corporation | Forms of 5-azacytidine |
US20060014949A1 (en) * | 2004-07-13 | 2006-01-19 | Supergen Inc. | Compositions and formulations of decitabine polymorphs and methods of use thereof |
US20060128654A1 (en) * | 2004-12-10 | 2006-06-15 | Chunlin Tang | Pharmaceutical formulation of cytidine analogs and derivatives |
US20060128653A1 (en) * | 2004-12-10 | 2006-06-15 | Chunlin Tang | Pharmaceutical formulation of decitabine |
EP2205073A4 (en) * | 2007-09-26 | 2013-03-06 | Sinai School Medicine | Azacytidine analogues and uses thereof |
EP2050757A1 (en) * | 2007-10-10 | 2009-04-22 | Cilag AG | Method of producing 2' -deoxy-5-azacytidine (Decitabine) |
EP2048151A1 (en) * | 2007-10-10 | 2009-04-15 | Cilag AG | Method for producing nucleosides by direct glycosylation of the nucleoside base |
PT3782612T (en) | 2008-05-15 | 2024-01-18 | Celgene Corp | Oral formulations of cytidine analogs and methods of use thereof |
WO2010014883A2 (en) | 2008-08-01 | 2010-02-04 | Dr. Reddy's Laboratories Ltd. | Azacitidine process and polymorphs |
KR20110026019A (en) | 2008-08-06 | 2011-03-14 | 시코르, 인크. | Process for preparing azacytidine intermediate |
AU2009279461B2 (en) | 2008-08-08 | 2014-01-23 | Scinopharm Taiwan, Ltd. | Process for making 5-azacytosine nucleosides and their derivatives |
ES2681529T3 (en) * | 2009-03-23 | 2018-09-13 | Ambit Biosciences Corporation | Treatment methods using combination therapy |
US20100249394A1 (en) * | 2009-03-26 | 2010-09-30 | Albemarle Corporation | Processes for producing decitabine |
IT1399195B1 (en) | 2010-03-30 | 2013-04-11 | Chemi Spa | PROCESS FOR THE SYNTHESIS OF AZACITIDINE AND DECITABINE |
MX2013010945A (en) | 2011-03-31 | 2014-03-12 | Celgene Internat Sarl | Systhesis of 5-azacytidine. |
RS57449B1 (en) | 2012-04-04 | 2018-09-28 | Halozyme Inc | Combination therapy with hyaluronidase and a tumor-targeted taxane |
CN103884809B (en) * | 2013-08-28 | 2016-01-27 | 鲁南制药集团股份有限公司 | A kind of analyzing detecting method of Decitabine intermediate |
JP6162349B1 (en) * | 2016-04-21 | 2017-07-12 | 大原薬品工業株式会社 | Sacyl moiety silyl ether derivatives of 5-azacytidines |
CN108226309B (en) | 2016-12-13 | 2020-06-16 | 江苏奥赛康药业有限公司 | Analysis method of dexrazoxane |
CN108239128B (en) | 2016-12-23 | 2019-03-29 | 江苏奥赛康药业股份有限公司 | The preparation method of beta-nucleosides class compound |
CN110128485B (en) * | 2018-02-09 | 2022-06-07 | 鲁南制药集团股份有限公司 | Preparation method of azacitidine |
US20190351031A1 (en) | 2018-05-16 | 2019-11-21 | Halozyme, Inc. | Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1244790B (en) * | 1963-10-29 | 1967-07-20 | Ceskoslovenska Akademie Ved | Process for the production of the cancerostatically effective 5-azacytidine |
GB1050899A (en) * | 1963-12-22 | |||
US3328388A (en) * | 1964-09-02 | 1967-06-27 | Merck & Co Inc | Arabinofuranosyl pyrimidines and methods of preparing same |
US3346561A (en) * | 1965-10-24 | 1967-10-10 | Merck & Co Inc | Pyrimidine 3-deoxynucleosides |
US3531464A (en) * | 1966-10-21 | 1970-09-29 | Us Health Education & Welfare | Alternative synthesis of 2'-deoxy-5-(trifluoromethyl)-uridine and the alphaanomer thereof |
CH527207A (en) * | 1968-05-08 | 1972-08-31 | Ceskoslovenska Akademie Ved | Process for the preparation of 1-glycosyl-5-azacytosines |
CH507969A (en) * | 1968-11-12 | 1971-05-31 | Ceskoslovenska Akademie Ved | Process for the preparation of 1-glycosyl-5-azacytosines |
CH532062A (en) * | 1968-11-13 | 1972-12-31 | Ceskoslovenska Akademie Ved | Process for the preparation of 1-glycosyl-5-azacytosines |
-
1970
- 1970-03-14 DE DE2012888A patent/DE2012888C3/en not_active Expired
-
1971
- 1971-02-08 FI FI333/71A patent/FI56018C/en active
- 1971-02-11 CS CS1030A patent/CS162741B2/cs unknown
- 1971-02-12 ES ES388193A patent/ES388193A1/en not_active Expired
- 1971-02-19 ZA ZA711084A patent/ZA711084B/en unknown
- 1971-03-03 CA CA106,797A patent/CA946379A/en not_active Expired
- 1971-03-08 IL IL36363A patent/IL36363A/en unknown
- 1971-03-10 CH CH352271A patent/CH552606A/en not_active IP Right Cessation
- 1971-03-10 AT AT206271A patent/AT313481B/en not_active IP Right Cessation
- 1971-03-11 DK DK115271A patent/DK152134C/en not_active IP Right Cessation
- 1971-03-12 SE SE7103210A patent/SE405253B/en unknown
- 1971-03-12 US US00123836A patent/US3817980A/en not_active Expired - Lifetime
- 1971-03-12 HU HUSCHE325*1A patent/HU164144B/hu unknown
- 1971-03-12 FR FR7108686A patent/FR2085707B1/fr not_active Expired
- 1971-03-12 BE BE764179A patent/BE764179A/en not_active IP Right Cessation
- 1971-03-13 PL PL1971146878A patent/PL81543B1/pl unknown
- 1971-03-15 JP JP1431371A patent/JPS5527077B1/ja active Pending
- 1971-03-15 NL NLAANVRAGE7103459,A patent/NL180835C/en not_active IP Right Cessation
- 1971-04-19 GB GB2338771*A patent/GB1351003A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
SU374828A3 (en) | 1973-03-20 |
FR2085707B1 (en) | 1975-04-18 |
FI56018C (en) | 1979-11-12 |
AT313481B (en) | 1974-02-25 |
PL81543B1 (en) | 1975-08-30 |
DE2012888A1 (en) | 1971-09-30 |
ES388193A1 (en) | 1973-05-01 |
CA946379A (en) | 1974-04-30 |
SE405253B (en) | 1978-11-27 |
BE764179A (en) | 1971-09-13 |
DE2012888B2 (en) | 1980-07-10 |
CH552606A (en) | 1974-08-15 |
JPS5527077B1 (en) | 1980-07-17 |
IL36363A (en) | 1974-05-16 |
NL180835B (en) | 1986-12-01 |
HU164144B (en) | 1973-12-28 |
FR2085707A1 (en) | 1971-12-31 |
GB1351003A (en) | 1974-04-24 |
DE2012888C3 (en) | 1981-04-02 |
NL7103459A (en) | 1971-09-16 |
DK152134B (en) | 1988-02-01 |
US3817980A (en) | 1974-06-18 |
CS162741B2 (en) | 1975-07-15 |
IL36363A0 (en) | 1971-05-26 |
ZA711084B (en) | 1971-10-27 |
DK152134C (en) | 1988-08-01 |
NL180835C (en) | 1987-05-04 |
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