FI49831C - Process for the preparation of 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-dibenzodiazepine-2-one. - Google Patents

Process for the preparation of 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-dibenzodiazepine-2-one.

Info

Publication number
FI49831C
FI49831C FI37370A FI37370A FI49831C FI 49831 C FI49831 C FI 49831C FI 37370 A FI37370 A FI 37370A FI 37370 A FI37370 A FI 37370A FI 49831 C FI49831 C FI 49831C
Authority
FI
Finland
Prior art keywords
dibenzodiazepine
dihydro
chloro
phenyl
methyl
Prior art date
Application number
FI37370A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI49831B (en
Inventor
Franjo Kajfez
Nikola Blazevic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of FI49831B publication Critical patent/FI49831B/fi
Publication of FI49831C publication Critical patent/FI49831C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI37370A 1969-10-16 1970-02-11 Process for the preparation of 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-dibenzodiazepine-2-one. FI49831C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1549969A CH537393A (en) 1969-10-16 1969-10-16 Process for the preparation of 1,4-benzodiazepine derivatives

Publications (2)

Publication Number Publication Date
FI49831B FI49831B (en) 1975-06-30
FI49831C true FI49831C (en) 1975-10-10

Family

ID=4409581

Family Applications (1)

Application Number Title Priority Date Filing Date
FI37370A FI49831C (en) 1969-10-16 1970-02-11 Process for the preparation of 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-dibenzodiazepine-2-one.

Country Status (7)

Country Link
JP (1) JPS5313637B1 (en)
CH (1) CH537393A (en)
DK (1) DK127428B (en)
FI (1) FI49831C (en)
NL (1) NL159973C (en)
NO (1) NO125095B (en)
SE (1) SE367632B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH578544A5 (en) * 1972-08-21 1976-08-13 Hoffmann La Roche
US4155904A (en) * 1973-02-08 1979-05-22 Schering Corporation Process for the preparation of 1,4-benzo-diazepines and 1,4-benzodiazepinones
US3996209A (en) * 1973-05-14 1976-12-07 Hoffmann-La Roche Inc. Process for preparing benzodiazepines

Also Published As

Publication number Publication date
DK127428B (en) 1973-11-05
DE2016084A1 (en) 1971-04-29
NL7001765A (en) 1971-04-20
SE367632B (en) 1974-06-04
NL159973C (en) 1979-09-17
NO125095B (en) 1972-07-17
CH537393A (en) 1973-05-31
FI49831B (en) 1975-06-30
JPS5313637B1 (en) 1978-05-11
DE2016084B2 (en) 1976-06-16

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