FI49715B - - Google Patents

Info

Publication number
FI49715B
FI49715B FI182766A FI182766A FI49715B FI 49715 B FI49715 B FI 49715B FI 182766 A FI182766 A FI 182766A FI 182766 A FI182766 A FI 182766A FI 49715 B FI49715 B FI 49715B
Authority
FI
Finland
Application number
FI182766A
Other languages
Finnish (fi)
Other versions
FI49715C (en
Inventor
Ronald Morton Cresswell
John William Mentha
Bernard Stuart Hurlbert
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to FI281169A priority Critical patent/FI49154C/en
Publication of FI49715B publication Critical patent/FI49715B/fi
Application granted granted Critical
Publication of FI49715C publication Critical patent/FI49715C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI182766A 1965-07-08 1966-07-07 Process for the preparation of antibacterial 2,4-diamino-5-benzylpyrimidines. FI49715C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI281169A FI49154C (en) 1965-07-08 1969-09-30 Novel hydrocinnamonitrile derivatives which are intermediates in the preparation of biologically active 2,4-diamino-5-benzylpyrimidines and process for their preparation.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47060665A 1965-07-08 1965-07-08

Publications (2)

Publication Number Publication Date
FI49715B true FI49715B (en) 1975-06-02
FI49715C FI49715C (en) 1975-09-10

Family

ID=23868272

Family Applications (1)

Application Number Title Priority Date Filing Date
FI182766A FI49715C (en) 1965-07-08 1966-07-07 Process for the preparation of antibacterial 2,4-diamino-5-benzylpyrimidines.

Country Status (6)

Country Link
BE (1) BE683875A (en)
BR (1) BR6681138D0 (en)
DE (1) DE1620729A1 (en)
FI (1) FI49715C (en)
IT (1) IT1062274B (en)
NL (1) NL6609626A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2065367C2 (en) * 1969-03-06 1985-04-04 The Wellcome Foundation Ltd., London Process for the preparation of 2,4-diamino-5-benzylpyrimidines
GB1261455A (en) * 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles
BR6915082D0 (en) 1969-05-16 1973-03-08 Wellcome Found PROCESS OF PREPARATION OF BENZYL-PYRIMIDINES
DE2051871A1 (en) * 1969-05-16 1971-11-18 The Wellcome Foundation Ltd., London Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents
BE792096A (en) * 1971-12-01 1973-05-30 Hoffmann La Roche NEW BENZYLPYRIMIDINES
BE795023A (en) * 1972-02-07 1973-08-06 Hoffmann La Roche NEW BENZYLPYRIMIDINES
EP0046856A3 (en) * 1980-08-29 1982-07-28 Hüls Troisdorf Aktiengesellschaft Process for preparing 4-amino-2-mercapto-pyrimidines
DE4333688C2 (en) * 1993-10-02 2003-11-06 Guenter Ege Process for the preparation of 3-aryl-2- (dialkoxymethyl) propannitriles and their conversion to 5-arylmethyl-2,4-diamino-pyrimidines, in particular to trimethoprim
CN107162989A (en) * 2017-05-27 2017-09-15 山东新华制药股份有限公司 A kind of preparation method of trimethoprim impurity

Also Published As

Publication number Publication date
FI49715C (en) 1975-09-10
BR6681138D0 (en) 1973-12-26
IT1062274B (en) 1984-02-29
BE683875A (en) 1967-01-09
NL6609626A (en) 1967-01-09
DE1620729A1 (en) 1970-08-20

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