FI42982C - Menetelmä terapeuttisesti arvokkaiden leurosidiini- ja/tai leurokristiinialkaloidien sekä niiden happoadditiosuolojen ja kvaternääristen ammoniumsuolojen eristämiseksi - Google Patents

Menetelmä terapeuttisesti arvokkaiden leurosidiini- ja/tai leurokristiinialkaloidien sekä niiden happoadditiosuolojen ja kvaternääristen ammoniumsuolojen eristämiseksi

Info

Publication number
FI42982C
FI42982C FI621927A FI192762A FI42982C FI 42982 C FI42982 C FI 42982C FI 621927 A FI621927 A FI 621927A FI 192762 A FI192762 A FI 192762A FI 42982 C FI42982 C FI 42982C
Authority
FI
Finland
Prior art keywords
leurocristine
leurosidine
alkaloids
isolating
quaternary ammonium
Prior art date
Application number
FI621927A
Other languages
English (en)
Other versions
FI42982B (fi
Inventor
Svoboda Gordon Howard
Armstrong Robert James
Barnes Jr Albert Johnson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI42982B publication Critical patent/FI42982B/fi
Application granted granted Critical
Publication of FI42982C publication Critical patent/FI42982C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G5/00—Alkaloids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI621927A 1961-10-26 1962-10-25 Menetelmä terapeuttisesti arvokkaiden leurosidiini- ja/tai leurokristiinialkaloidien sekä niiden happoadditiosuolojen ja kvaternääristen ammoniumsuolojen eristämiseksi FI42982C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US147911A US3205220A (en) 1961-10-26 1961-10-26 Leurosidine and leurocristine and their production

Publications (2)

Publication Number Publication Date
FI42982B FI42982B (fi) 1970-09-02
FI42982C true FI42982C (fi) 1970-12-10

Family

ID=22523426

Family Applications (1)

Application Number Title Priority Date Filing Date
FI621927A FI42982C (fi) 1961-10-26 1962-10-25 Menetelmä terapeuttisesti arvokkaiden leurosidiini- ja/tai leurokristiinialkaloidien sekä niiden happoadditiosuolojen ja kvaternääristen ammoniumsuolojen eristämiseksi

Country Status (9)

Country Link
US (1) US3205220A (fi)
BE (1) BE624076A (fi)
BR (1) BR6240221D0 (fi)
CH (1) CH451953A (fi)
DK (1) DK119613B (fi)
ES (1) ES281689A1 (fi)
FI (1) FI42982C (fi)
GB (1) GB981579A (fi)
OA (1) OA02582A (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE763730R (fr) * 1971-01-15 1971-08-02 Omnium Chimique Sa Procede de preparation de la vincamine naturelle a partir de latabersonine et derives indoliques
US3932417A (en) * 1973-10-24 1976-01-13 Eli Lilly And Company Dimeric indole alkaloid purification process
US4075214A (en) * 1976-05-17 1978-02-21 Eli Lilly And Company Preparation of leurosidine and novel leurosidine 4'-ethers and esters
US4110330A (en) * 1977-05-27 1978-08-29 Eli Lilly And Company 5'-Acetonylvincristine and related compounds
HU178084B (en) * 1977-05-31 1982-03-28 Richter Gedeon Vegyeszet New process for the extraction of native vindoline,catharantine,3',4'-anhydrovinblastine,leurosine and,if desired,of other diinodle alkaloids from vinca rosea l.drogue
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
US4259242A (en) * 1978-10-10 1981-03-31 Eli Lilly And Company Method of preparing vindesine sulfate
HU178706B (en) * 1979-04-23 1982-06-28 Richter Gedeon Vegyeszet Process for preparing bis-indole alkaloids and acid addition salts thereof
US4619935A (en) * 1983-03-17 1986-10-28 Eli Lilly And Company Stable oncolytic formulations
US4558053A (en) * 1983-12-21 1985-12-10 Eli Lilly And Company Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
US4749787A (en) * 1986-10-23 1988-06-07 Harbor Branch Oceanographic Institution, Inc. Process of isolating vinblastine from the plant catharanthis roseus
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US4923876A (en) * 1988-04-18 1990-05-08 Cetus Corporation Vinca alkaloid pharmaceutical compositions
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
US20040127435A1 (en) * 2002-08-02 2004-07-01 Regents Of The University Of California Uses for inhibitors of inosine monophosphate dehydrogenase
MX2018011102A (es) 2016-03-15 2019-01-10 Oryzon Genomics Sa Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos.
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2509051A (en) * 1946-04-17 1950-05-23 Applezweig Norman Extraction of alkaloids from fresh plants

Also Published As

Publication number Publication date
BE624076A (fr) 1963-04-25
FI42982B (fi) 1970-09-02
ES281689A1 (es) 1963-02-01
OA02582A (fr) 1970-05-05
DK119613B (da) 1971-02-01
DE1445689A1 (de) 1969-01-23
GB981579A (en) 1965-01-27
BR6240221D0 (pt) 1973-06-14
CH451953A (de) 1968-05-15
US3205220A (en) 1965-09-07

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