FI4275597T3 - Non-invasive sensor and measuring method - Google Patents
Non-invasive sensor and measuring method Download PDFInfo
- Publication number
- FI4275597T3 FI4275597T3 FIEP22173132.6T FI22173132T FI4275597T3 FI 4275597 T3 FI4275597 T3 FI 4275597T3 FI 22173132 T FI22173132 T FI 22173132T FI 4275597 T3 FI4275597 T3 FI 4275597T3
- Authority
- FI
- Finland
- Prior art keywords
- radiation
- model
- partitioned
- environment
- target
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 32
- 238000001514 detection method Methods 0.000 claims description 78
- 230000006978 adaptation Effects 0.000 claims description 52
- 238000004088 simulation Methods 0.000 claims description 44
- 238000004422 calculation algorithm Methods 0.000 claims description 13
- 238000000691 measurement method Methods 0.000 claims description 12
- 241000607479 Yersinia pestis Species 0.000 claims description 6
- 238000004590 computer program Methods 0.000 claims description 3
- 230000005855 radiation Effects 0.000 claims 38
- 238000010586 diagram Methods 0.000 claims 8
- 238000005259 measurement Methods 0.000 description 43
- 210000003491 skin Anatomy 0.000 description 31
- 230000004044 response Effects 0.000 description 27
- 239000008280 blood Substances 0.000 description 25
- 210000004369 blood Anatomy 0.000 description 25
- 230000008569 process Effects 0.000 description 20
- 230000000875 corresponding effect Effects 0.000 description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 18
- 238000012545 processing Methods 0.000 description 17
- 210000000434 stratum corneum Anatomy 0.000 description 17
- 238000005265 energy consumption Methods 0.000 description 16
- 210000002615 epidermis Anatomy 0.000 description 15
- 230000035945 sensitivity Effects 0.000 description 15
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 12
- 230000001276 controlling effect Effects 0.000 description 9
- 239000008103 glucose Substances 0.000 description 9
- 230000006870 function Effects 0.000 description 8
- 238000010895 photoacoustic effect Methods 0.000 description 7
- 238000010521 absorption reaction Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 5
- 238000000126 in silico method Methods 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 238000001727 in vivo Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000010200 validation analysis Methods 0.000 description 4
- 101150066718 FMOD gene Proteins 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000002596 correlated effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- GNFTZDOKVXKIBK-UHFFFAOYSA-N 3-(2-methoxyethoxy)benzohydrazide Chemical compound COCCOC1=CC=CC(C(=O)NN)=C1 GNFTZDOKVXKIBK-UHFFFAOYSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 238000013473 artificial intelligence Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000001902 propagating effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000013517 stratification Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 238000012549 training Methods 0.000 description 2
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 description 1
- 229910005542 GaSb Inorganic materials 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000005305 interferometry Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
- A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/171—Systems in which incident light is modified in accordance with the properties of the material investigated with calorimetric detection, e.g. with thermal lens detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
- G01N2021/1706—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids in solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
- G01N2021/1731—Temperature modulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Artificial Intelligence (AREA)
- Optics & Photonics (AREA)
- Fuzzy Systems (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Evolutionary Computation (AREA)
- Analytical Chemistry (AREA)
- Signal Processing (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- General Physics & Mathematics (AREA)
- Mathematical Physics (AREA)
- Biochemistry (AREA)
- Primary Health Care (AREA)
- General Business, Economics & Management (AREA)
- Databases & Information Systems (AREA)
- Business, Economics & Management (AREA)
- Data Mining & Analysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Acoustics & Sound (AREA)
- Emergency Medicine (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22173132.6A EP4275597B1 (fr) | 2022-05-12 | 2022-05-12 | Capteur non invasif et procede de mesure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI4275597T3 true FI4275597T3 (en) | 2024-09-26 |
Family
ID=82019281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP22173132.6T FI4275597T3 (en) | 2022-05-12 | 2022-05-12 | Non-invasive sensor and measuring method |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP4275597B1 (enExample) |
| JP (1) | JP2025518671A (enExample) |
| KR (1) | KR20250016168A (enExample) |
| CN (1) | CN119421662A (enExample) |
| DK (1) | DK4275597T3 (enExample) |
| FI (1) | FI4275597T3 (enExample) |
| WO (1) | WO2023217998A1 (enExample) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6574490B2 (en) * | 2001-04-11 | 2003-06-03 | Rio Grande Medical Technologies, Inc. | System for non-invasive measurement of glucose in humans |
| JP5186044B2 (ja) * | 2009-07-28 | 2013-04-17 | パナソニック株式会社 | 血糖値推定装置 |
| WO2015162215A1 (en) * | 2014-04-25 | 2015-10-29 | Helmholtz Zentrum München Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) | Device and method for frequency-domain thermoacoustic sensing |
-
2022
- 2022-05-12 EP EP22173132.6A patent/EP4275597B1/fr active Active
- 2022-05-12 FI FIEP22173132.6T patent/FI4275597T3/sv active
- 2022-05-12 DK DK22173132.6T patent/DK4275597T3/da active
-
2023
- 2023-05-11 KR KR1020247040956A patent/KR20250016168A/ko not_active Withdrawn
- 2023-05-11 WO PCT/EP2023/062675 patent/WO2023217998A1/fr not_active Ceased
- 2023-05-11 JP JP2024566772A patent/JP2025518671A/ja active Pending
- 2023-05-11 CN CN202380039860.3A patent/CN119421662A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4275597B1 (fr) | 2024-07-03 |
| JP2025518671A (ja) | 2025-06-19 |
| WO2023217998A1 (fr) | 2023-11-16 |
| EP4275597A1 (fr) | 2023-11-15 |
| CN119421662A (zh) | 2025-02-11 |
| KR20250016168A (ko) | 2025-02-03 |
| DK4275597T3 (da) | 2024-10-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20200170553A1 (en) | Measuring apparatus and measuring method | |
| US20110184683A1 (en) | Methods and systems for analyte measurement | |
| CN101917899B (zh) | 用于测定分析物浓度的光学传感器 | |
| US6157041A (en) | Methods and apparatus for tailoring spectroscopic calibration models | |
| CN104665840A (zh) | 无创血糖测量方法及指端测量探头 | |
| CN1331570A (zh) | 具有改进光学界面的无创伤血液分析物测定方法 | |
| CN118121196B (zh) | 一种hct预测方法、系统、设备及介质 | |
| JP2014188045A (ja) | 被検体情報取得装置および被検体情報取得方法 | |
| US12622587B2 (en) | Non-invasive sensor and measuring method | |
| KR20250016168A (ko) | 비침습적 센서 및 측정 방법 | |
| EP4403095A1 (en) | Process for detecting acoustic leaks in a non-invasive sensor based on indirect photoacoustic detection | |
| CN116322481A (zh) | 光声葡萄糖传感器、系统和方法 | |
| EP4368097A1 (en) | Process for non-invasively analyzing a multilayer medium | |
| EP4144292B1 (en) | Process and analyte monitor for estimating a quantity in mathematical relationship with an analyte concentration level in a target | |
| WO2025237534A1 (en) | Process for detecting acoustic leaks in a non-invasive sensor based on indirect photoacoustic detection | |
| JP2025509821A5 (enExample) | ||
| Emmerich et al. | A data-driven two-microphone method for in-situ sound absorption measurements | |
| Parvitte et al. | Quantitative finite element modelling of compact photoacoustic gas sensors | |
| Trabelsi et al. | Visible and near-infrared laser radiation in a biological tissue. A forward model for medical imaging by optical tomography | |
| Wadamori et al. | Photoacoustic depth profiling of a skin model for non-invasive glucose measurement | |
| JP7625146B1 (ja) | 生体成分測定装置および生体成分測定方法 | |
| CN118948273B (zh) | 血糖浓度检测方法、装置及设备 | |
| US20250152061A1 (en) | Method and system for predicting bladder urine volume | |
| WO2023210208A1 (ja) | 成分濃度推定システム及び成分濃度推定方法 | |
| Aghili et al. | Data-efficient extraction of optical properties from 3D Monte Carlo TPSFs using Bi-LSTM transfer learning |