FI20225321A1 - An adhesive body dressing and a method for manufacturing an adhesive body dressing - Google Patents
An adhesive body dressing and a method for manufacturing an adhesive body dressing Download PDFInfo
- Publication number
- FI20225321A1 FI20225321A1 FI20225321A FI20225321A FI20225321A1 FI 20225321 A1 FI20225321 A1 FI 20225321A1 FI 20225321 A FI20225321 A FI 20225321A FI 20225321 A FI20225321 A FI 20225321A FI 20225321 A1 FI20225321 A1 FI 20225321A1
- Authority
- FI
- Finland
- Prior art keywords
- layer
- hydrocolloid
- composition
- adhesive
- component
- Prior art date
Links
- 239000000853 adhesive Substances 0.000 title claims abstract description 351
- 230000001070 adhesive effect Effects 0.000 title claims abstract description 346
- 238000000034 method Methods 0.000 title claims abstract description 19
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 8
- 239000000416 hydrocolloid Substances 0.000 claims abstract description 375
- 239000010410 layer Substances 0.000 claims abstract description 260
- 239000012790 adhesive layer Substances 0.000 claims abstract description 233
- 239000000463 material Substances 0.000 claims abstract description 177
- 229920000642 polymer Polymers 0.000 claims abstract description 44
- 239000002028 Biomass Substances 0.000 claims abstract description 21
- 239000006260 foam Substances 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 215
- 230000008719 thickening Effects 0.000 claims description 71
- 230000002745 absorbent Effects 0.000 claims description 51
- 239000002250 absorbent Substances 0.000 claims description 51
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 42
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 42
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 34
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 27
- 150000004676 glycans Chemical class 0.000 claims description 26
- 229920001282 polysaccharide Polymers 0.000 claims description 26
- 239000005017 polysaccharide Substances 0.000 claims description 26
- 229920002125 Sokalan® Polymers 0.000 claims description 21
- 235000013877 carbamide Nutrition 0.000 claims description 21
- 239000004202 carbamide Substances 0.000 claims description 21
- 229920000747 poly(lactic acid) Polymers 0.000 claims description 21
- 229940001004 aluminium glycinate Drugs 0.000 claims description 20
- RUJUQAPQALJUPC-UHFFFAOYSA-K bis[(2-aminoacetyl)oxy]alumanyl 2-aminoacetate Chemical compound [Al+3].NCC([O-])=O.NCC([O-])=O.NCC([O-])=O RUJUQAPQALJUPC-UHFFFAOYSA-K 0.000 claims description 20
- 235000011187 glycerol Nutrition 0.000 claims description 19
- 239000004584 polyacrylic acid Substances 0.000 claims description 19
- 229920002678 cellulose Polymers 0.000 claims description 17
- 239000001913 cellulose Substances 0.000 claims description 17
- 239000004626 polylactic acid Substances 0.000 claims description 17
- 150000001875 compounds Chemical class 0.000 claims description 16
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims description 15
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 14
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 14
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 14
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 14
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 13
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 12
- 229920005989 resin Polymers 0.000 claims description 12
- 239000011347 resin Substances 0.000 claims description 12
- 239000001993 wax Substances 0.000 claims description 12
- 229920000728 polyester Polymers 0.000 claims description 10
- 229920003232 aliphatic polyester Polymers 0.000 claims description 5
- 229920000098 polyolefin Polymers 0.000 claims description 5
- 229920002807 Thiomer Polymers 0.000 claims description 3
- 230000002378 acidificating effect Effects 0.000 claims description 2
- 229920001277 pectin Polymers 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 238000012360 testing method Methods 0.000 description 36
- 239000003292 glue Substances 0.000 description 13
- 239000004480 active ingredient Substances 0.000 description 11
- 239000000126 substance Substances 0.000 description 9
- 239000012943 hotmelt Substances 0.000 description 8
- 230000002093 peripheral effect Effects 0.000 description 8
- -1 poly(lactic acid) Polymers 0.000 description 8
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 description 6
- 208000027418 Wounds and injury Diseases 0.000 description 6
- 229920002988 biodegradable polymer Polymers 0.000 description 6
- 239000004621 biodegradable polymer Substances 0.000 description 6
- 239000008213 purified water Substances 0.000 description 6
- 206010052428 Wound Diseases 0.000 description 5
- 230000035876 healing Effects 0.000 description 5
- 239000000017 hydrogel Substances 0.000 description 5
- 230000007794 irritation Effects 0.000 description 5
- 241000366182 Melaleuca alternifolia Species 0.000 description 4
- 125000001931 aliphatic group Chemical group 0.000 description 4
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 4
- 239000000499 gel Substances 0.000 description 4
- 231100001231 less toxic Toxicity 0.000 description 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 238000009264 composting Methods 0.000 description 3
- 150000002894 organic compounds Chemical class 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 2
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 description 2
- 229940015975 1,2-hexanediol Drugs 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 description 2
- 229920002498 Beta-glucan Polymers 0.000 description 2
- 235000009024 Ceanothus sanguineus Nutrition 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 235000015459 Lycium barbarum Nutrition 0.000 description 2
- BNMGUJRJUUDLHW-HCZMHFOYSA-N Madecassoside Chemical compound O([C@@H]1[C@@H](CO)O[C@H]([C@@H]([C@H]1O)O)OC[C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)[C@]12CC[C@H]([C@@H]([C@H]1C=1[C@@]([C@@]3(C[C@@H](O)[C@H]4[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]4(C)[C@H]3CC=1)C)(C)CC2)C)C)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O BNMGUJRJUUDLHW-HCZMHFOYSA-N 0.000 description 2
- BNMGUJRJUUDLHW-HLUHVYOBSA-N Madecassoside Natural products C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5[C@H](O)C[C@@]34C)[C@@H]2[C@H]1C)C(=O)O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O[C@@H]8O[C@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O BNMGUJRJUUDLHW-HLUHVYOBSA-N 0.000 description 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 229920002385 Sodium hyaluronate Polymers 0.000 description 2
- CKZZREIPBTYJEQ-UHFFFAOYSA-N Totarol Natural products C1CC2C(C)(C)CCCC2(C)C2=C1C(C(C)C)=C(C)C=C2 CKZZREIPBTYJEQ-UHFFFAOYSA-N 0.000 description 2
- QCYLIQBVLZBPNK-UHFFFAOYSA-N asiaticoside A Natural products O1C(C(=O)C(C)C)=CC(C)C(C2(C(OC(C)=O)CC34C5)C)C1CC2(C)C3CCC(C1(C)C)C45CCC1OC1OCC(O)C(O)C1O QCYLIQBVLZBPNK-UHFFFAOYSA-N 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 description 2
- KCIDZIIHRGYJAE-YGFYJFDDSA-L dipotassium;[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate Chemical compound [K+].[K+].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@H]1O KCIDZIIHRGYJAE-YGFYJFDDSA-L 0.000 description 2
- 150000002148 esters Chemical group 0.000 description 2
- 229940100524 ethylhexylglycerin Drugs 0.000 description 2
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 description 2
- 229940114124 ferulic acid Drugs 0.000 description 2
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 description 2
- 235000001785 ferulic acid Nutrition 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 229940070818 glycyrrhizate Drugs 0.000 description 2
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 2
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 description 2
- 229920002674 hyaluronan Polymers 0.000 description 2
- 229960003160 hyaluronic acid Drugs 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 229940090813 madecassoside Drugs 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 150000002772 monosaccharides Chemical class 0.000 description 2
- 229960003966 nicotinamide Drugs 0.000 description 2
- 235000005152 nicotinamide Nutrition 0.000 description 2
- 239000011570 nicotinamide Substances 0.000 description 2
- 239000003235 non-water-soluble binding agent Substances 0.000 description 2
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 2
- 229960003471 retinol Drugs 0.000 description 2
- 235000020944 retinol Nutrition 0.000 description 2
- 239000011607 retinol Substances 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- 229940010747 sodium hyaluronate Drugs 0.000 description 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- ZRVDANDJSTYELM-FXAWDEMLSA-N totarol Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C)C1=C2C(C(C)C)=C(O)C=C1 ZRVDANDJSTYELM-FXAWDEMLSA-N 0.000 description 2
- 229940074347 totarol Drugs 0.000 description 2
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 description 2
- 229960000401 tranexamic acid Drugs 0.000 description 2
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 2
- ZRVDANDJSTYELM-UHFFFAOYSA-N trans-totarol Natural products C1CC2C(C)(C)CCCC2(C)C2=C1C(C(C)C)=C(O)C=C2 ZRVDANDJSTYELM-UHFFFAOYSA-N 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 244000144927 Aloe barbadensis Species 0.000 description 1
- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000003643 Callosities Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 125000002353 D-glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- MNQZXJOMYWMBOU-VKHMYHEASA-N D-glyceraldehyde Chemical compound OC[C@@H](O)C=O MNQZXJOMYWMBOU-VKHMYHEASA-N 0.000 description 1
- BDAGIHXWWSANSR-UHFFFAOYSA-N Formic acid Chemical compound OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 231100000694 OECD Guidelines for the Testing of Chemicals Toxicity 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 208000004210 Pressure Ulcer Diseases 0.000 description 1
- 229920001131 Pulp (paper) Polymers 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010040925 Skin striae Diseases 0.000 description 1
- 208000031439 Striae Distensae Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 241001464837 Viridiplantae Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000011358 absorbing material Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 239000001140 aloe barbadensis leaf extract Substances 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- 229940069638 aloe vera leaf extract Drugs 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 229920000704 biodegradable plastic Polymers 0.000 description 1
- 229920000229 biodegradable polyester Polymers 0.000 description 1
- 239000004622 biodegradable polyester Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000010815 organic waste Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 239000010816 packaging waste Substances 0.000 description 1
- 229920001748 polybutylene Polymers 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 239000004632 polycaprolactone Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000010526 radical polymerization reaction Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000007151 ring opening polymerisation reaction Methods 0.000 description 1
- 238000007127 saponification reaction Methods 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0246—Adhesive bandages or dressings characterised by the skin-adhering layer
- A61F13/0253—Adhesive bandages or dressings characterised by the skin-adhering layer characterized by the adhesive material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0289—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/15203—Properties of the article, e.g. stiffness or absorbency
- A61F13/15252—Properties of the article, e.g. stiffness or absorbency compostable or biodegradable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/58—Adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/62—Compostable, hydrosoluble or hydrodegradable materials
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Manufacturing & Machinery (AREA)
- Materials For Medical Uses (AREA)
- Adhesives Or Adhesive Processes (AREA)
Abstract
The invention relates to an adhesive body dressing (10) comprising a backing layer (B) and a hydrocolloid adhesive layer (H), the backing layer (B) is a film layer or a foam layer comprising a first side (B1) and a second side (B2), the backing layer (B) and the hydrocolloid adhesive layer (H) being made of biodegradable material. The backing layer (B) comprises a backing material layer (20) made of material comprising polymers derived from renewable biomass sources. The invention further relates to method for manufacturing an adhesive body dressing.
Description
AN ADHESIVE BODY DRESSING AND A METHOD FOR MANUFACTURING AN
ADHESIVE BODY DRESSING
The present invention relates to an adhesive body dressing and more particularly to an adhesive body dressing according to the preamble of claim 1. The present invention also relates to a method for manufacturing an adhesive body dressing and more particularly to a method according to preamble of claim 15.
Hydrocolloid adhesive dressings are generally known for many different uses as polymer dressings. These hydrocolloid adhesive dressings are used as body or skin dressings for improving or preventing any skin related medical or esthetical concerns such as wounds, blisters, acne, corns, cracked skin, burns, pressure ulcers, scarring or stretch marks. dressings for dermal ulcers, burns and other exudative wounds.
The hydrocolloid adhesive dressings are used for certain time depending on the purpose of use. After use, the hydrocolloid adhesive dressings are removed from the body and skin and discarded. The hydrocolloid material in the hydrocolloid adhesive dressing absorbs moisture from the skin or body creating advantageous healing conditions for a wound or advantageous treatment conditions for skin. At the same time the hydrocolloid adhesive composition is susceptibility to breakdown and detachment from the skin upon swelling due to absorbed moisture. This together with external wearing limit the use time of the
N hydrocolloid adhesive dressing. < Due to the relative short-term use of the hydrocolloid adhesive < 25 dressings as wound dressings and dressings for blisters or the like, they are often = removed and discarded in acute situations. Thus, the hydrocolloid adhesive
T dressings may often end nature and landfills where they may remain causing long-
E term waste problems. — One of the problems associated with the prior art is that many materials & 30 and compositions which are typically used in adhesive body dressings causes
N allergic reactions to a skin.
N Furthermore, hydrocolloid adhesive dressings should conform with body curves with relative low stress.
Furthermore, a backing layer of a hydrocolloid adhesive dressing is usually comprises some non-renewable material.
An object of the present invention is to provide an adhesive body dressing and the method for manufacturing an adhesive body dressing so as to solve or at least alleviate the prior art problems.
The objects of the invention are achieved by an adhesive dressing which is characterized by what is stated in independent claim 1. The objects of the invention are further achieved by a method which is characterized by what is stated in independent claim 15.
The preferred embodiments of the invention are disclosed in the dependent claims.
The invention is based on the idea of providing an adhesive body dressing comprising a backing layer and a hydrocolloid adhesive layer. The backing layer is a film layer or a foam layer comprising a first side and a second side. The hydrocolloid adhesive layer is provided on the first side of backing layer. The backing layer and the hydrocolloid adhesive layer being made of biodegradable material. The backing layer comprises a backing material layer made of material comprising polymers derived from renewable biomass sources, and the hydrocolloid adhesive layer comprises a hydrocolloid material layer made of a hydrocolloid adhesive composition comprising a thickening component and an absorbent component.
The backing material layer made of material comprising polymers derived from renewable biomass sources reduces irritation of a skin when the
N 25 adhesive body dressing is used.
N In the context of this application term “biodegradable” means that
S material or substance can be completely converted into water, CO2, and biomass
N through the action of microorganisms such as fungi and bacteria. This property is
I not dependent on the origin of the raw materials, but only on the chemical & 30 composition of the polymers. Further, biodegradability of polymers is
N appropriately described by test and assessment methods in international
O standards. Industrial composting is today a well-established disposal process for
S organic waste materials. One test of biodegradability is the controlled composting
N test according to ISO 14855.
Additionally, ISO 17088:2021, the European standard EN 13432:2000 and the American standard ASTM D 6400 define basic requirements for packaging and packaging materials to be considered as biodegradable and compostable in industrial composting facilities.
In the context of this application biodegradable polymer material and term biodegradable mean a polymer based material which fulfils requirements for a biodegradable and compostable polymer material according to one or more of the following standards: ISO 17088:2012, ISO 14855-1:2012, ISO 14855-2:2018,
ISO 16929:2021, ISO 20200:2015, EN 13432:2000, ASTM D5338, ASTM D6400, and OECD Guidelines for the Testing of Chemicals — Guideline 208: Terrestrial
Plants, Growth Test.
EN 13432:2000 is a harmonised European standard linked to the
European Directive on Packaging and Packaging Waste (94/62/EC). ..
Biodegradable product producers use this standard and certification schemes developed upon this standard to show that their products are compostable.
In one embodiment, the backing layer B and the hydrocolloid adhesive layer H being made of biodegradable material fulfilling criteria of compostable material according to EN 13432:2000.
In one embodiment, the backing layer B and the hydrocolloid adhesive layer H being made of compostable material according to EN 13432:2000.
In one embodiment, the biodegradable material being compostable material according to EN 13432:2000.
In one embodiment, the adhesive body dressing being made of compostable material according to EN 13432:2000.
In one embodiment, the thickening component of the hydrocolloid adhesive composition is derived from renewable biomass sources.
N In an alternative embodiment, the thickening component of the
N hydrocolloid adhesive composition is derived from plant biomass.
S In another alternative, the thickening component of the hydrocolloid
N adhesive composition is derived from a polysaccharide comprising source.
E 30 The hydrocolloid adhesive composition is derived from a > polysaccharide comprising source is well adapted on a skin.
N In a yet another alternative embodiment, the thickening component of
O the hydrocolloid adhesive composition being a structural acidic
S heteropolysaccharide or a thickening component being a cellulose derivate.
Cellulose is suitable source for the thickening component as cellulose has no taste, is odorless, is hydrophilic and cellulose is widely produced.
In a yet another alternative embodiment, the thickening component of the hydrocolloid adhesive composition being pectic polysaccharides or the thickening component of the hydrocolloid adhesive composition being carboxymethyl cellulose or the thickening component of the hydrocolloid adhesive composition is derived from carboxymethyl cellulose; or
In a yet another alternative embodiment, the thickening component of the hydrocolloid adhesive composition being carboxymethyl cellulose or the thickening component of the hydrocolloid adhesive composition is derived from carboxymethyl cellulose; or
In a yet another alternative embodiment, the thickening component of the hydrocolloid adhesive composition is derived from natural cellulose.
Cellulose allows for less toxic products than non-water-soluble binders.
In a yet another alternative embodiment, the thickening component of the hydrocolloid adhesive composition being a salt of carboxymethyl cellulose.
In a yet another alternative embodiment, the thickening component of the hydrocolloid adhesive composition being sodium carboxymethyl cellulose.
Water solubility of sodium carboxymethyl cellulose allows for less toxic and costly products than with non-water-soluble binders
In one embodiment, the absorbent component of the hydrocolloid adhesive composition being polymer.
In alternative embodiment, the absorbent component of the hydrocolloid adhesive composition being polyolefin.
In another alternative embodiment, the absorbent component of the hydrocolloid adhesive composition being mucoadhesive polymer; or
N In a yet another alternative embodiment, the absorbent component of
N the hydrocolloid adhesive composition being polyacrylic acid.
S Polyacrylic acid (PAA) is a polymer with the formula (CH2-CHC02H)n.
N Polyacrylic acid is a polyolefin polymer. Polyacrylic acid is a super-adsorbent
E 30 suitable biocompatible matrices for medical applications such as gels. Crosslinked > hydrogels of PAA and the thickening component may be used as a glue
N In one embodiment, the hydrocolloid adhesive composition comprising
O 10 - 80 wt% the thickening component and 20 - 90 wt% the absorbent
S component, based on the total weight of the composition.
In an alternative embodiment, the hydrocolloid adhesive composition comprising 10 - 80 wt% the thickening component and 20 - 90 wt% the absorbent component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
Crosslinked hydrogels of the absorbent component and the thickening 5 component may be used as a glue
In an another alternative embodiment, the hydrocolloid adhesive composition comprising 10 - 50 wt% the thickening component obtained from a compound comprising polysaccharides, 20 - 50 wt% the absorbent component, and 20 wt% - 35 wt% water component, based on the total weight of the — composition.
Crosslinked hydrogels of absorbent component and the thickening component may be used as a glue
In a yet another alternative embodiment, the hydrocolloid adhesive composition comprising 10 - 50 wt% the thickening component obtained from a compound comprising polysaccharides, 20 - 50 wt% the absorbent component, and 20 wt% - 35 wt% water component, based on the total weight of the composition, and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
Crosslinked hydrogels of absorbent component and the thickening component may be used as a glue and the water component provides for less toxic products.
The water component may be purified water.
In a yet another alternative embodiment, the hydrocolloid adhesive composition comprising 10 - 50 wt% the thickening component obtained from a compound comprising polysaccharides, 20 - 50 wt% the absorbent component,
N and 27 wt% - 32 wt% water component, based on the total weight of the
N composition, and with the proviso that components of the hydrocolloid adhesive
S composition taken together adds up to 100 wt%.
N Crosslinked hydrogels of absorbent component and the thickening
E 30 component may be used as a glue and the water component provides for less toxic > products.
N The water component may be purified water.
O In one embodiment, the hydrocolloid adhesive composition further comprising 1
S wt% - 5 wt% glyserin component, based on the total weight of the composition.
In alternative embodiment, the hydrocolloid adhesive composition further comprising 1 wt% - 5 wt% glyserin component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
In another alternative embodiment, the hydrocolloid adhesive composition further comprising 2 wt% - 4 wt% glyserin component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
Glyserin having antimicrobial and antiviral properties
In one embodiment, the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,5 wt% carbamide component, based on the total weight of the composition.
Carbamide promotes rehydration of the skin.
In an alternative embodiment, the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,25 wt% carbamide component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
In an alternative embodiment, the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,15 wt% aluminium glycinate component, based on the total weight of the composition.
Aluminium glycinate neutralizes acidity.
In another alternative embodiment, the hydrocolloid adhesive composition further comprising 0,05 wt% - 0,15 wt% aluminium glycinate component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
In a yet another alternative embodiment, the hydrocolloid adhesive
N composition further comprising 0,1 wt% - 0,5 wt% carbamide component and
N 0,05 wt% - 0,15 wt% aluminium glycinate component, based on the total weight
S of the composition and with the proviso that components of the hydrocolloid
N adhesive composition taken together adds up to 100 wt%.
E 30 In a yet another alternative embodiment, the hydrocolloid adhesive > composition further comprising 0,1 wt% - 0,5 wt% carbamide component and
N 0,05 wt% - 0,15 wt% aluminium glycinate component, based on the total weight
O of the composition and with the proviso that components of the hydrocolloid
S adhesive composition taken together adds up to 100 wt%.
In one embodiment, the hydrocolloid adhesive layer having a first side and a second side, the hydrocolloid adhesive layer having a hydrocolloid adhesive layer thickness in a direction between the first side and the second side, and the hydrocolloid adhesive layer thickness being more than 0,05 mm or more than 0,1 mm.
In an alternative embodiment, the hydrocolloid adhesive layer thickness being between 0,1 mm and 10 mm.
In another alternative embodiment, and the hydrocolloid adhesive layer thickness being between 0,2 mm and 5 mm.
In a yet another alternative embodiment, the hydrocolloid adhesive layer thickness being between 0,2 mm and 0,5 mm.
In a yet another alternative embodiment, the hydrocolloid adhesive layer thickness being between 0,05 mm and 0,2 mm.
The thickness of the hydrocolloid adhesive layer is provided with a material thickness such that adequate material volume is achieved for adsorption of body fluids during use of the adhesive body dressingln one embodiment, the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,3 wt% dipotassium glycyrrhizate component, based on the total weight of the composition.
In an alternative embodiment, the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,3 wt% dipotassium glycyrrhizate component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
Dipotassium glycyrrhizate accelerate the skin healing process.
N In one embodiment, the hydrocolloid adhesive composition comprises
N 35 wt% - 45 wt% the absorbent component, the absorbent component being
S polyacrylic acid, 20 wt% - 30 wt% the thickening component, the thickening
N component of the hydrocolloid adhesive composition being sodium
I 30 carboxymethyl cellulose, 25 wt% - 35 wt% water component, and 2 wt% - 4 wt% > glycerin, based on the total weight of the composition.
N This composition forms a strong structure with the backing layer, sticks
O on a skin and accelerates the skin healing process .
S In an alternative embodiment, the hydrocolloid adhesive composition comprises 35 wt% - 45 wt% the absorbent component, the absorbent component being polyacrylic acid, 20 wt% - 30 wt% the thickening component, the thickening component of the hydrocolloid adhesive composition being sodium carboxymethyl cellulose, 25 wt% - 35 wt% water component, and 2 wt% - 4 wt% glycerin, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
This composition forms a strong structure with the backing layer, sticks on a skin and accelerates the skin healing process.
In one embodiment, the hydrocolloid adhesive composition comprises: - 35 wt% - 45 wt% the absorbent component, the absorbent component being polyacrylic acid, - 20 wt% - 30 wt% the thickening component, the thickening component of the hydrocolloid adhesive layer being sodium carboxymethyl cellulose, - 25 wt% - 35 wt% a water component, - 2 wt% - 4 wt% a glycerin component, -0,1wt% - 0,5 wt% a carbamide component, - 0,05 wt% - 0,15 wt% an aluminium glycinate component, and -0,1 wt% - 0,3 wt% a dipotassium glycyrrhizate component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
This composition forms a strong structure with the backing layer, sticks on a skin and accelerates the skin healing process.
In other words, the water component consists of water or purified water, the glycerin component consist of glycerin, the carbamide component consists of carbamide, the aluminium glycinate component consists of aluminium — glycinate, and the dipotassium glycyrrhizate component consists of dipotassium
N glycyrrhizate.
N [n an alternative embodiment, the backing layer having a backing layer
S thickness in a direction between the first side and the second side, and the backing
N layer thickness being between 20 um and 40 pm.
E 30 The relatively small thickness of the backing layer provides necessary > surface layer for the hydrocolloid adhesive layer without making the adhesive body
N dressing unnecessary thick.
O In one embodiment, the backing layer is made of biodegradable
S material or compostable material comprising polyester.
In an alternative embodiment, the backing layer is made of biodegradable material or compostable material comprising aliphatic polyester.
In another alternative embodiment, the backing layer is made of compostable material comprising aliphatic polyester.
In a yet another alternative embodiment, the backing layer is made of compostable material comprising polylactic acid.
In a yet another alternative embodiment, the backing layer is made of compostable material comprising polylactic acid 50 - 100 wt%, based on the total weight of the composition.
Polylactic acid, also known as poly(lactic acid) or polylactide (abbreviation PLA) is a thermoplastic polyester. PLA is aliphatic polyester. PLA has become a popular material due to it being economically produced from renewable resources. PLA is compostable.
In one embodiment, the hydrocolloid adhesive layer having a first side and a second side, the second side of the hydrocolloid adhesive layer facing towards the first side of the baking layer, and the adhesive body dressing comprises an additional adhesive layer made of biodegradable material or compostable material, the additional adhesive layer is provided between the first side of the baking layer and the second side of the hydrocolloid adhesive layer.
In an alternative embodiment, the hydrocolloid adhesive layer having a first side and a second side, the second side of the hydrocolloid adhesive layer facing towards the first side of the baking layer, and the adhesive body dressing comprises an additional adhesive layer, the additional adhesive layer is provided between the first side of the baking layer and the second side of the hydrocolloid adhesive layer, and the additional adhesive layer is made of an additional adhesive layer composition comprising waxes, resins and polymer, and the adhesive layer composition being biodegradable or compostable.
N In another alternative embodiment, the hydrocolloid adhesive layer
N having a first side and a second side, the second side of the hydrocolloid adhesive
S layer facing towards the first side of the baking layer, and the adhesive body
N dressing comprises an additional adhesive layer, the additional adhesive layer is
E 30 provided between the first side of the baking layer and the second side of the > hydrocolloid adhesive layer, and the additional adhesive layer comprises an
N additional adhesive layer composition comprising 5 wt% - 30 wt% waxes, 40 wt%
O - 90 wt% resins and 5 wt% - 30 wt% polymer, based on the total weight of the
S composition, and the adhesive layer composition being biodegradable or compostable.
In a yet another alternative embodiment, the hydrocolloid adhesive layer having a first side and a second side, the second side of the hydrocolloid adhesive layer facing towards the first side of the baking layer, and the adhesive body dressing comprises an additional adhesive layer comprises an additional adhesive layer composition, the additional adhesive layer is provided between the first side of the baking layer and the second side of the hydrocolloid adhesive layer, and the adhesive layer composition comprises 5 wt% - 30 wt% waxes, 40 wt% - 90 wt% resins and 5 wt% - 30 wt% polymer, based on the total weight of the composition, and the additional adhesive layer composition being biodegradable or compostable and with the proviso that components of the adhesive layer — composition taken together adds up to 100 wt%.
This composition of the additional adhesive layer improves flexibility of the backing layer made of a biodegradable material comprising polymers derived from renewable biomass sources
In one embodiment, the additional adhesive layer having an additional adhesive layer thickness between the second side of the hydrocolloid adhesive layer and the first side of the backing layer, and the additional adhesive layer thickness being more than 0,05 mm or more than 0,1 mm.
In an alternative embodiment, the additional adhesive layer thickness being between 0,05 mm and 10 mm or between 0,1 mm and 10 mm.
In another alternative embodiment, and the additional adhesive layer thickness being between 0,2 mm and 5 mm.
In a yet another alternative embodiment, the additional adhesive layer thickness being between 0,2 mm and 0,5 mm.n a yet another alternative embodiment, the additional adhesive layer thickness being between 0,05 mm and 0,5 mm.
N In one embodiment, ahydrocolloid adhesive layer having a first side
N and a second side, the second side of the hydrocolloid adhesive layer is provided in
S contact with the first side of the bakinglayer, the adhesive body dressing comprises
N a first removable covering layer provided on the first side of hydrocolloid adhesive
E 30 layer, and the first removable covering layer is made of biodegradable material or > compostable material.
N Thus, the adhesive surface of the adhesive body dressing which is to be
O placed against the skin of the user may be kept clean without deterioration before
S use. Furthermore, an adhesive body dressing which is fully biodegradable or compostable is achieved.
In an alternative embodiment, a hydrocolloid adhesive layer having a first side and a second side, the second side of the hydrocolloid adhesive layer is provided in contact with the first side of the baking layer, the adhesive body dressing comprises a second removable covering layer provided on the second side of the baking layer, and the second removable covering layer is made of biodegradable material or compostable material.
The second removable covering layer is used to protect the backing layer before the adhesive body dressing is placed on a skin. In some embodiments the second removable covering layer increases durability of the adhesive body dressing is used before it is placed on a skin
In another alternative embodiment, a hydrocolloid adhesive layer having a first side and a second side, the second side of the hydrocolloid adhesive layer is provided in contact with the first side of the baking layer, the adhesive body dressing comprises a first removable covering layer provided on the first side of hydrocolloid adhesive layer, and the first removable covering layer is made of biodegradable material or compostable material, the adhesive body dressing comprises a second removable covering layer provided on the second side of the baking layer, and the second removable covering layer is made of biodegradable material or compostable material. of the baking layer, and the second removable covering layer is made of biodegradable material or compostable material.
In one embodiment, the hydrocolloid adhesive layer is made of fully absorbing material. In other words, the hydrocolloid adhesive layer does not deliver any therapeutically active ingredient on a skin.
In the context of this application, a therapeutically active ingredient means any natural or synthetic substance which may heal or relief symptoms caused by an injury or a decease or a discomfort, which may act as a vaccine,
N which may be used for change any property of a skin or which may affect an
N appearance of a skin.
S In an alternative embodiment, the hydrocolloid adhesive layer
N comprises a therapeutically active ingredient.
E 30 In another alternative embodiment, the hydrocolloid adhesive layer > comprises microneedles.
N In a yet another alternative embodiment, the hydrocolloid adhesive layer comprises microneedles comprising the therapeutically active ingredient so
S that the microneedles are arranged to dissolve and deliver gradually the therapeutically active ingredient through a skin.
In one embodiment, the hydrocolloid adhesive layer comprises a therapeutically active ingredient and the hydrocolloid adhesive layer thickness being between 0,05 mm and 0,2 mm or between 0,05 mm and 0,5 mm.
In one embodiment, the therapeutically active ingredient being niacinamide or tranexamic acid or ferulic acid or salicylic acid or aloe vera leaf extract or retinol or totarol or beta Glucan or hyaluronic acid or sodium hyaluronate or melaleuca alternifolia (tea tree) leaf oil or butylene glycol or propanediol, 1,2-Hexanediol or madecassoside or dipotassium glycyrrhizate, or caprylyl glycol or ethoxydiglycol or ethylhexylglycerin any combination thereof.
In one embodiment, the microneedles having a microneedle height, and — the microneedle height being between 0,05 mm and 2 mm.
In one embodiment, the microneedles comprising a microneedle base and a microneedle tip, the microneedle base is provided on the first side of the hydrocolloid adhesive layer, the microneedles protruding from the microneedle base in a direction away from the backing layer, the microneedle base having a —microneedle base width, and the microneedle height being between 2 and 4 times the microneedle base width.
In one embodiment, the hydrocolloid adhesive layer comprises 2 - 1000 pcs. microneedles / cm2 or 50 - 500 pcs. microneedles / cm2.
In embodiment, the microneedles comprise polyvinyl alcohol (PVA).The present invention also relates to a method for manufacturing an adhesive body dressing having a hydrocolloid adhesive layer and a backing layer.
The method comprises forming a backing layer of a biodegradable material comprising polymers derived from renewable biomass source and providing an adhesive hydrocolloid layer on the backing layer. The adhesive hydrocolloid layer being made of biodegradable hydrocolloid adhesive composition comprising a
N thickening component and absorbent component of the hydrocolloid adhesive
N layer.
S In one embodiment, the method comprises providing an additional
N adhesive layer between the backing layer and the adhesive hydrocolloid layer.
E 30 The additional adhesive layer improves flexibility of the adhesive body > dressing.
N In one embodiment, the adhesive body dressing being any above disclosed embodiment of an adhesive body dressing.
N An advantage of the invention is that materials of the adhesive body dressing according to the invention are well adapted with users of the adhesive body dressing and the adhesive body dressing degrades in nature diminishing waste problem and providing environmentally friendly adhesive body dressing.
Furthermore, material of backing is made biodegradable material comprising polymers derived from renewable biomass source.
The invention is described in detail by means of specific embodiments with reference to the enclosed drawings, in which
Figure 1 shows schematically general structure of one embodiment of an adhesive body dressing according to the present invention;
Figure 2 shows schematically an upper view of an adhesive body dressing;
Figure 3 shows schematically a bottom view of an adhesive body dressing;
Figures 4 - 13 show schematically general structure of different embodiments of an adhesive body dressing according to the present invention;
Figure 14 shows schematically a further embodiment of an adhesive body dressing according to the present invention; and
Figure 15 shows schematically general structure of one embodiment of an adhesive body dressing according to the present invention.
Figure 1 shows schematically a general structure of one embodiment of an adhesive body dressing 10. The adhesive body dressing 10 comprises a 3 backing layer B comprising a backing material layer 20. The backing layer B being
S 25 — on top surface of the adhesive body dressing 10. The adhesive body dressing 3 further comprises a hydrocolloid adhesive layer H comprising a hydrocolloid
N adhesive material layer 30. The hydrocolloid adhesive layer being on bottom > surface of the adhesive body dressing 10. The backing layer B is made of & biodegradable material and the hydrocolloid adhesive layer H is made of
N 30 biodegradable material. a In the context of this application hydrocolloid adhesive layer comprises
N one or more layers of the hydrocolloid adhesive material. Hydrocolloid material or
N hydrocolloid adhesive material or hydrocolloid dressing material refers to a flexible sheet which contains material that forms a gel in the presence of water. — Hydrocolloid dressing material may be adhered to the skin without the use of adhesives or separate taping, as the hydrocolloid adhesive material or hydrocolloid dressing material is self-adhesive or comprises self-adhesive properties.
In contact with a fluid (e.g., a wound exudate, pus, oil, blood, etc.), the the hydrocolloid material of the hydrocolloid adhesive layer H absorb water and swell, forming a gel which is held within the structure of the adhesive matrix. The gel which is formed as a result of the absorption of fluid is not mobile and free running but held within the structure of the adhesive matrix. Suitably, a hydrocolloid dressing is waterproof.
In one embodiment, the hydrocolloid adhesive layer H is made of compostable material.
The backing layer B and the hydrocolloid adhesive layer H are superposed. The backing layer B comprises a first side B1 and a second side B2.
The hydrocolloid adhesive layer H is provided on the first side B1 of backing layer
B. Thus, the backing layer B and the hydrocolloid adhesive layer H are superposed inthe structure of the adhesive body dressing 10. A first side H1 of the hydrocolloid adhesive layer H is arranged to be placed against a skin of the user.
In other words, the first side B1 of the backing layer B facing towards the hydrocolloid adhesive layer H.
In one embodiment, the hydrocolloid adhesive layer H is arranged to protrude from the backing layer B.
In one embodiment, the hydrocolloid adhesive layer H is provided directly on the backing material layer 20.
The backing layer B is a film layer or a foam layer.
In the context of this application the film layer is a continuous form of material and the foam layer is a layer formed by trapping pockets of gas in a liquid
N or solid.
N In a preferred embodiment, the film layer and the foam layer being
S homogeneous material.
N
E 30 In one embodiment, the backing layer B is made of compostable > material.
N In one embodiment, the backing material layer 20 of the backing layer
O B is made of biobased aliphatic biobased polyesters. Biobased aliphatic biobased
S polyesters are biodegradable polymers. Most synthetic polyesters are not biodegradable. Aliphatic biobased polyesters having an open-chain structure.
Polyester is a category of polymers that contain the ester functional group in every repeat unit of their main chain. Biobased aliphatic biobased polyesters have excellent biodegradability and biocompatibility. Starch-based bioplastics are often blended with biodegradable polyesters to produce starch/polylactic acid, starch/polycaprolactone or polybutylene adipate-co- terephthalate produced by blends. These blends are also compostable.
In one embodiment, the backing layer B is made of compostable material comprising polylactic acid. Polylactic acid, also known as poly(lactic acid) or polylactide (abbreviation PLA) is a thermoplastic polyester with backbone formula (C3H402)n or [-C(CH3)HC(=0)0-]n, formally obtained by condensation of lactic acid C(CH3)(OH)HCOOH with loss of water (hence its name). It can also be prepared by ring-opening polymerization oflactide [ -C(CH3)HC(=0)0-];, the cyclic dimer of the basic repeating unit.
The backing layer B having a backing layer thickness BT in a direction between the first side B1 and the second side B2, and
In one embodiment, the backing layer thickness BT being between 10 um and 50 pm.
In an alternative embodiment, the backing layer thickness BT being between 20 um and 40 um.
The hydrocolloid adhesive material layer 30 of the hydrocolloid adhesive layer (H) comprises a hydrocolloid adhesive composition comprising 10 - 50 wt% a thickening component obtained from a compound comprising polysaccharides and 20 - 80 wt% absorbent component, based on the total weight of the composition.
A thickening component is a substance which increases the viscosity of the composition.
N Natural saccharides are generally composed of simple carbohydrates
N called monosaccharides with general formula (CH20), where n is three or more.
S Examples of monosaccharides are glucose, fructose, and glyceraldehyde.
N Polysaccharides, meanwhile, have a general formula of Cx(H20)y where x is usually
E 30 alarge number between 200 and 2500. When the repeating units in the polymer = backbone are six-carbon monosaccharides, as is often the case, the general formula
N simplifies to (C6H1005)n, where typically 40 < n < 3000.
O Cellulose is an example of structural polysaccharides. Cellulose is an
S organic compound with the formula (C6H1005)n, a polysaccharide consisting of a — linear chain of several hundred to many thousands of B(1—4) linked D-glucose units.
Cellulose is an important structural component of the primary cell wall of green plants. Cellulose for industrial use is mainly obtained from wood pulp and cotton.
Carboxymethyl cellulose (CMC) or cellulose gum is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone. It is often used as its sodium salt, sodium carboxymethyl cellulose.
In the context of this application, the thickening component obtained from a compound comprising from polysaccharides being a chemical derived from an element with the formula (C6H1005)n.
In the context of this application, the thickening component of the hydrocolloid adhesive layer H derived from a polysaccharide comprising source means that the thickening component is produced from a compound comprising polysaccharides such as cellulose.
In other words, the thickening component derived from a polysaccharide comprising source may be a cellulose derivate with carboxymethyl groups or sodium carboxymethyl cellulose (CsH15Na03j.
It should be noted that in the context of this application derived and derivative means that there may be one or more process steps to obtain the final formula from the source.
It should be noted that in the context of this application a polysaccharide comprising source means that the source comprises a compound comprising polysaccharide as one element. In other words, the polysaccharide comprising source may comprise compounds comprising polysaccharide and other elements.
N The absorbent component of the hydrocolloid adhesive composition
N having an ability to absorb and retain water and swell to many times to its original
S volume.
N In one embodiment, the absorbent component of the hydrocolloid
I 30 adhesive composition being polymer. > In an alternative embodiment, the absorbent component of the
N hydrocolloid adhesive composition being polyolefin.
O In another alternative embodiment, the absorbent component of the
S hydrocolloid adhesive composition being mucoadhesive polymer.
In a yet another alternative embodiment, the absorbent component of the hydrocolloid adhesive composition being polyacrylic acid.
Polyacrylic acid (PAA) is a polymer with the formula (CH2-CHCO2H)n. It is a derivative of acrylic acid (CH,=CHCO:H). Polyacrylic acid is a polyolefin. It can be viewed as polyethylene with carboxylic acid (CO2H) substituents on alternating carbons. PAA is produced by free radical polymerization. Initiators include potassium persulfate and azobisisobutyronitrile (AIBN). AIBN is an organic compound with the formula [(CH3)2C(CN)]2N2.
In one embodiment, the hydrocolloid adhesive composition comprising - 50 wt% a thickening component obtained from a compound comprising polysaccharides, 20 - 50 wt% absorbent component, and 20 wt% - 35 wt% water, 10 — based on the total weight of the composition, based on the total weight of the composition.
In an alternative embodiment, the hydrocolloid adhesive composition comprising 10 - 50 wt% a thickening component obtained from a compound comprising polysaccharides, 20 - 50 wt% absorbent component, and 27 wt% - 32 wt% water, based on the total weight of the composition, based on the total weight of the composition.
In one embodiment, the hydrocolloid adhesive composition comprising 1 wt% - 5 wt% glyserin, based on the total weight of the composition.
In an alternative embodiment, the hydrocolloid adhesive composition comprising 2 wt% - 4 wt% glyserin, based on the total weight of the composition.
Glycerol also called glycerine in British English and glycerin in
American English is a simple polyol compound. Glycerol is generally obtained from plant and animal sources where it occurs in triglycerides, esters of glycerol with long-chain carboxylic acids . The hydrolysis, saponification, or transesterification — ofthesetriglycerides produces glycerol as well as the fatty acid derivative. Glyserol
N having a chemical formula C3H303,
N In one embodiment, the hydrocolloid adhesive composition comprising
S 0,1 wt% - 0,5 wt% carbamide, based on the total weight of the composition.
N In an alternative embodiment, the hydrocolloid adhesive composition
I 30 comprising 0,1 wt% - 0,25 wt% carbamide, based on the total weight of the > composition.
N Carbamide, also known as urea, is an organic compound with chemical formula CO(NHz)2. o
In one embodiment, the hydrocolloid adhesive composition comprising 0,1 wt% - 0,15 wt% aluminium glycinate, based on the total weight of the composition.
In an alternative embodiment, he hydrocolloid adhesive composition comprising 0,05 wt% - 0,15 wt% aluminium glycinate, based on the total weight of the composition.
Aluminium glycinate having a formula of C2HgAINOs,
In one embodiment, the hydrocolloid adhesive composition comprising 0,1 wt% - 0,3 wt% dipotassium glycyrrhizate, based on the total weight of the composition.
Dipotassium glycyrrhizate having a formula of C42H6oK2016.
In one embodiment hydrocolloid adhesive composition comprises: - 35 wt% - 45 wt% absorbent component, the absorbent component being polyacrylic acid, - 20 wt% - 30 wt% thickening component, the thickening component of the hydrocolloid adhesive layer (H) being sodium carboxymethyl cellulose, - 25 wt% - 35 wt% water, and - 2 wt% - 4 wt% glycerin, based on the total weight of the composition.
In a alternative embodiment, the hydrocolloid adhesive composition consists of: - 35 wt% - 45 wt% absorbent component, the absorbent component being polyacrylic acid, - 20 wt% - 30 wt% thickening component, the thickening component of the hydrocolloid adhesive layer H being sodium carboxymethyl cellulose, - 25 wt% - 35 wt% water, - 2 wt% - 4 wt% glycerin,
N - 0,1 wt% - 0,5 wt% carbamide,
N - 0,05 wt% - 0,15 wt% aluminium glycinate, and
S - 0,1 wt% - 0,3 wt% dipotassium glycyrrhizate
N based on the total weight of the composition.
E 30 In one embodiment, the hydrocolloid adhesive layer H having a first > side H1 and a second side H2, the hydrocolloid adhesive layer H having a
N hydrocolloid adhesive layer thickness HT in a direction between the first side H1
O and the second side HZ, and the hydrocolloid adhesive layer thickness HT being
S more than 0,1 mm.
In an alternative embodiment, the hydrocolloid adhesive layer thickness HT being between 0,1 mm and 10 mm.
In another alternative embodiment, and the hydrocolloid adhesive layer thickness HT being between 0,2 mm and 5 mm.
In a yet another alternative embodiment, the hydrocolloid adhesive layer thickness HT being between 0,2 mm and 0,5 mm.
It should be noted, that the size and shape of the adhesive body dressing of the present invention may vary and the present invention is not restricted to any particular shape or size.
Figure 2 shows schematically a top view, figure 3 shows schematically a bottom view and figure 4 shows schematically general structure of one 10 embodiment of an adhesive body dressing according to the present invention. The adhesive body dressing 10 comprises a backing material layer 20 on top surface of the adhesive body dressing 10. The adhesive body dressing further comprises a hydrocolloid adhesive material layer 30 on bottom surface of the adhesive body dressing 10.
It should be noted, that the size and shape of the adhesive body dressing 10 of the present invention may vary and the present invention is not restricted to any particular shape or size.
In this embodiment, the backing material layer 20 is larger than the hydrocolloid adhesive material layer 30. Thus, the surface area of the backing material layer 20 is larger than the surface area of the hydrocolloid adhesive material layer 30, as shown in figure 3. Accordingly, the hydrocolloid adhesive material layer 30 is provided at peripheral distance BO from the peripheral edges of the backing material layer 20. The backing material layer 20 extends beyond the hydrocolloid adhesive material layer 30 or the peripheral edges of the hydrocolloid adhesive material layer 30 such that the peripheral area BO is provided. This
N enables the hydrocolloid adhesive material layer 30 to be protected and not to be
N exposed during use of the adhesive body dressing. The hydrocolloid adhesive
S material layer 30 remains covered between the backing material layer 20 and the
N skin of the user and against the skin of the user.
E 30 The backing material layer 20 may comprises any above disclosed > material of the backing layer B and the hydrocolloid adhesive material layer 30
N may comprises any above disclosed composition of the hydrocolloid adhesive H.
O Figure 5 shows one embodiment in which the backing layer B
S comprises the surface backing material layer 20 and an intermediate backing material layer 40. The intermediate backing material layer 40 is provided between the surface backing material layer 20 and the hydrocolloid adhesive layer H.
The intermediate backing material layer 40 is arranged against the bottom surface 22 of the surface backing material layer 20 and the upper surface of the hydrocolloid adhesive layer H. The upper surface of the hydrocolloid adhesive layer H being on the second side H2 of the hydrocolloid adhesive layer H.
In some embodiments, the intermediate backing material layer 40 is an intermediate elastomer layer.
In some embodiments, the intermediate backing material layer 40 comprises or is made of biodegradable biopolyesters.
The intermediate backing material layer 40 comprises an intermediate — top surface 44 and an intermediate bottom surface 42, as shown in figure 9. The intermediate top surface 44 of the intermediate backing material layer 40 is arranged towards or against the surface backing material layer 20 and/or the bottom surface 22 thereof. The intermediate bottom surface 42 of the intermediate backing material layer 40 is arranged towards or against the hydrocolloid adhesive layer H.
The surface backing material layer 20 or the intermediate backing material layer 40 may be adhesive or self-adhesive for bonding the surface backing material layer 20 and the intermediate backing material layer 40 together.
The intermediate bottom surface 42 of the intermediate backing material layer 40 is arranged towards or against the hydrocolloid adhesive layer H, as shown in figure 9. The intermediate bottom surface 42 of the intermediate backing material layer 40 or the intermediate backing material layer 40 may be adhesive or self-adhesive for attaching to the hydrocolloid adhesive layer H and/or to the skin at the peripheral area A.
Figure 6 shows schematically general structure of different
N embodiments of an adhesive body dressing according to the present invention.
N The hydrocolloid adhesive layer H may comprise one or more
S hydrocolloid material layers which are made of or comprise same or different
N hydrocolloid materials.
E 30 The one or more hydrocolloid material layers are preferably made of or > comprise any embodiment of above disclosed a hydrocolloid adhesive
N composition.
O In the embodiment of figures 4 and 10, the hydrocolloid adhesive layer
S H comprise only one hydrocolloid adhesive material layer 30.
The hydrocolloid adhesive material layer 30 comprises a hydrocolloid top surface 34 and a hydrocolloid bottom surface 32, as shown in figure 10. The hydrocolloid bottom surface 32 of the hydrocolloid adhesive material layer 30 forms bottom surface of the adhesive body dressing 10 and an active surface of the adhesive body dressing 10 which is to be placed against the skin of the user.
The hydrocolloid adhesive material layer 30 and the hydrocolloid bottom surface 32 thereof is usually self-adhesive for attachment to skin of the user. Alternatively, the hydrocolloid bottom surface 32 of the hydrocolloid adhesive material layer 30 may be provided with additional adhesive layer (not shown). The additional adhesive layer is preferably made of biodegradable or compostable adhesive material.
The hydrocolloid top surface 34 of the hydrocolloid adhesive material layer 30 is arranged towards or against the backing material layer B, or the surface backing material layer 20 and/or the bottom surface 22 thereof, or the intermediate backing material layer 40 and/or the intermediate bottom surface 42 thereof.
The hydrocolloid adhesive material layer 30 may be adhesive or self- adhesive for attaching the hydrocolloid adhesive material layer 30 and the backing layer B together.
Figures 6, 7 and 11 show an alternative embodiment in which the hydrocolloid adhesive layer H comprises a first hydrocolloid adhesive material layer 50 and a second hydrocolloid adhesive material layer 60. The first hydrocolloid adhesive material layer 50 is provided between the backing layer B and the second hydrocolloid adhesive material layer 60.
The first hydrocolloid adhesive material layer 50 and the second hydrocolloid adhesive material layer 60 are preferably made of or comprise biodegradable or compostable polymer materials.
N The first hydrocolloid adhesive material layer 50 comprises a first
N hydrocolloid top surface 54 and a first hydrocolloid bottom surface 52, as shown
S in figure 11. The second hydrocolloid adhesive material layer 60 comprises a
N second hydrocolloid top surface 64 and a second hydrocolloid bottom surface 62.
I 30 The first hydrocolloid top surface 54 forms the hydrocolloid top surface > 34 and the second hydrocolloid bottom surface 62 forms the bottom surface of the
N active surface of the adhesive body dressing 10 to be placed against skin of the user.
O The first hydrocolloid bottom surface 52 and the second hydrocolloid
S top surface 64 are arranged towards or against each other.
It should be noted that the hydrocolloid adhesive layer H may comprise one or more hydrocolloid adhesive material layers 30, 50, 60 made of same or different material or hydrocolloid materials or comprises same or different hydrocolloid substances.
Similarly, the backing layer may comprise one or more backing material layers 20, 40 made of or comprising same or different biodegradable polymer — materials.
Figure 12 shows an embodiment of the adhesive body dressing 10 in which a first removable covering layer CF provided on a first side H2 of the hydrocolloid adhesive layer H or on the bottom or active bottom surface of the adhesive body dressing 10. The first covering layer CF may be a conventional release liner which is used to protect the exposed active surface of the hydrocolloid adhesive layer H, and optionally the exposed portion of the backing layer B, the peripheral area A. The first covering layer CF is removed just before applying the adhesive body dressing 10 to skin of the user.
A second removable covering layer CS is provided the top surface of the backing layer B or the top surface 24 of the backing material layer 20 or the second side B2 of the backing layer B for preventing wrinkling, curling or deteriorating of the edges of backing layer B. The second covering layer CS may support the exposed periphery of backing layer B during application of the adhesive body dressing 10 to skin of the user. Once the adhesive body dressing 10 is in place on — the skin, the second covering layer is removed.
The first and/or second removable covering layers CF, CS may also comprise or made of biodegradable polymer material. The biodegradable polymer material of the first and/or second removable covering layers CF, CS may be made of or comprise one of the biodegradable polymer materials mentioned above in connection with the backing layer B.
N Alternatively, the first and/or second removable covering layer may be
N made of biodegradable paper-based material or some biodegradable material.
S Figure 12 shows an embodiment of the adhesive body dressing 10 in
N which the adhesive body dressing comprises an additional adhesive layer A made
E 30 — of biodegradable material or compostable material. The hydrocolloid adhesive > layer H having a first side H1 and a second side H2, the second side H2 of the
N hydrocolloid adhesive layer H facing towards the first side B1 of the baking layer B
O and the additional adhesive layer A is provided between the first side B1 of the
S baking layer B and the second side H2 of the hydrocolloid adhesive layer H.
In other words, the hydrocolloid adhesive layer H, the additional adhesive layer A and the baking layer B being superposed.
In one embodiment, the additional adhesive layer A is made of an additional adhesive layer composition comprising waxes, resins and polymer.
In an alternative embodiment, the additional adhesive layer A is made of an additional adhesive layer composition comprising 5 wt% - 30 wt% waxes, 40 wt% -90 wt% resins and 5 wt% - 30 wt% polymer, based on the total weight of the composition; or
In another alternative embodiment, the additional adhesive layer A is made of an additional adhesive layer composition comprising 5 wt% - 30 wt% waxes, 40 wt% - 90 wt% resins and 5 wt% - 30 wt% polymer, based on the total weight of the composition.
Figure 14 shows a schematic cross sectional view of the adhesive body dressing 10. The hydrocolloid adhesive layer H has a larger thickness in the central portion of the adhesive body dressing 10 than in the peripheral portions of the hydrocolloid adhesive layer H. Thus, the thickness of the hydrocolloid adhesive layer H decreases from the central portion of the adhesive body dressing 10 towards the edges of the adhesive body dressing 10 or towards the peripheral areas A. This may provide the structure of the adhesive body dressing 10 more resistant to wear and enhance the attachment of the adhesive body dressing 10 skin during use.
Figure 15 shows schematically general structure of one embodiment of an adhesive body dressing according to the present invention.
In this embodiment, the hydrocolloid adhesive layer H comprises microneedles 50.
In one embodiment, the hydrocolloid adhesive layer H comprises
N microneedles 50 comprising the therapeutically active ingredient so that the
N microneedles 50 are arranged to dissolve and deliver gradually the therapeutically
S active ingredient through a skin.
N In one embodiment, the hydrocolloid adhesive layer H comprises a
E 30 therapeutically active ingredient and the hydrocolloid adhesive layer thickness HT = being between 0,05 mm and 0,2 mm or between 0,05 mm and 0,5 mm.
N In one embodiment, the therapeutically active ingredient being
O niacinamide or tranexamic acid or ferulic acid or salicylic acid or aloe vera leaf
S extract or retinol or totarol or beta Glucan or hyaluronic acid or sodium hyaluronate or melaleuca alternifolia (tea tree) leaf oil or butylene glycol or propanediol, 1,2-Hexanediol or madecassoside or dipotassium glycyrrhizate, or caprylyl glycol or ethoxydiglycol or ethylhexylglycerin any combination thereof.
In one embodiment, the microneedles 50 having a microneedle height
NH, and the microneedle height NH being between 0,05 mm and 2 mm.
In one embodiment, the microneedles 50 comprising a microneedle base 51 and a microneedle tip 52, the microneedle base 51 is provided on the first side H1 of the hydrocolloid adhesive layer H, the microneedles 50 protruding from the microneedle base 51 in a direction away from the backing layer B, the microneedle base 51 having a microneedle base width NW, and the microneedle height NH being between 2 and 4 times the microneedle base width NW.
Inone embodiment, the hydrocolloid adhesive layer H comprises microneedles 50 2 pcs - 1000 pcs / cm2 or 50 pcs - 500 pcs / cm2.
The present invention further provides a method for manufacturing an adhesive body dressing 10 having a hydrocolloid adhesive layer H and a backing layer B, the method comprises: - forming a backing layer B of a biodegradable material; and - providing an adhesive hydrocolloid layer H on the backing layer B, the adhesive hydrocolloid layer H being made of biodegradable material and the adhesive hydrocolloid layer H comprises 10 - 50 wt% a thickening component obtained from a compound comprising polysaccharides and 20 - 80 wt% absorbent component, based on the total weight of the composition.
In one embodiment, the backing layer B being any above disclosed embodiment of the adhesive hydrocolloid layer H.
In one embodiment, the adhesive hydrocolloid layer H being any above
N disclosed embodiment of the adhesive hydrocolloid layer H.
N In one embodiment, the adhesive body dressing 10 being any above
S disclosed embodiment of the adhesive body dressing 10.
N
E 30 The invention has been described above with reference to the examples > shown in the figures. However, the invention is in no way restricted to the above
N examples but may vary within the scope of the claims.
LÖ
S
N
Example 1 (comparative example)
An adhesive body dressing is produced on the laboratory. The hydrocolloid adhesive layer is produced as follows: 28 wt% hot melt glue; 35 wt% carboxymethyl cellulose powder; 15 wt% polyisobutylene; 17 wt% Xanthan gum rin; and 5 wt% naphthenic oil is stirred and a hydrocolloid adhesive is obtained. A typical commercially available compostable film is supplied for a backing layer. The film has a thickness of 20 um. The compostable film is made of material comprising polymers obtained from renewable biomass sources. The polymers comprise — polylactic acid. The adhesive body dressings are produced such that an additional adhesive layer made of a hot melt glue is provided on the backing layer. The hot melt glue is made of compostable material and it comprises 18 wt% waxes, 64 wt% resins and 18 wt% polymers, based on the total weight of the composition. The adhesive layer has thickness of 0,3 mm.
Finally, the hydrocolloid adhesive layer having a 0,3 mm thickness is used to cover the adhesive layer to provide an adhesive body dressing.
The adhesive body dressing was worn by six volunteer test subjects for the purpose of determining its characteristics with duration of adhesion and general convenience. The adhesive body dressing was worn between 24 and 48 — hours by the test subjects.
After a test adhesive body dressing was removed from a test subject, the results were evaluated on the basis of a multiple-choice questionnaire.
All test adhesive body dressing was remained on the skin until a test subject decided to detach a test adhesive body dressing. Two of the test subjects reported an irritation on a skin.
S
N Example 2 (comparative example) 3
N An adhesive body dressing of the invention is produced on the laboratory. The
E 30 hydrocolloid adhesive layer is produced as follows: 40 wt% polyacrylic acid; 26,5 > wt% sodium carboxymethyl cellulose; 30 wt% purified water; 3 wt% glycerin; 0,15
N wt% carbamide; 0,1 wt% aluminium glycinate, and 0,2 wt% dipotassium
O glycyrrhizate is stirred and hydrocolloid adhesive is obtained. A typical
S commercially available film comprising polytetrafluoroethylene and polyurethane — is supplied for a backing layer.
Finally, the hydrocolloid adhesive layer having a 0,3 mm thickness is used to cover the adhesive layer to provide an adhesive body dressing.
The adhesive body dressing was worn by the six volunteer test subjects for the purpose of determining its characteristics with duration of adhesion and general convenience. The adhesive body dressing was worn between 24 and 48 hours by the test subjects.
After a test adhesive body dressing was removed from a test subject, the results were evaluated on the basis of a multiple-choice questionnaire.
All test adhesive body dressing was remained on the skin until a test subject decided to detach a test adhesive body dressing.
One of the subjects reported a slight irritation on a skin in the vicinity of the edge of the test adhesive body dressing
Example 3 in accordance with the invention
An adhesive body dressing of the invention is produced on the laboratory. The hydrocolloid adhesive layer is produced as follows: 40 wt% polyacrylic acid; 26,5 wt% sodium carboxymethyl cellulose; 30 wt% purified water; 3 wt% glycerin; 0,15 wt% carbamide; 0,1 wt% aluminium glycinate, and 0,2 wt% dipotassium glycyrrhizate is stirred and hydrocolloid adhesive is obtained. A typical commercially available compostable film comprising polymers obtained from renewable biomass sources is supplied for a backing layer. The compostable film is made of material comprising polymers obtained from renewable biomass sources. The polymers in the backing layer are polylactic acid.
Finally, the hydrocolloid adhesive layer having a 0,3 mm thickness is used to cover the adhesive layer to provide an adhesive body dressing.
N The adhesive body dressing was worn by the six volunteer test subjects
N for the purpose of determining its characteristics with duration of adhesion and
S general convenience. The adhesive body dressing was worn between 24 and 48
N hours by the test subjects.
E 30 After a test adhesive body dressing was removed from a test subject, > the results were evaluated on the basis of a multiple-choice questionnaire.
N All test adhesive body dressing was remained on the skin until a test
O subject decided to detach a test adhesive body dressing.
S None of the subjects reported an irritation on a skin.
The inventors surprisingly found out that an adhesive body dressing having a backing layer made of compostable material comprising polymers obtained from renewable biomass sources does not irritate a skin of the adhesive body dressing user.
Example 4 in accordance with the invention
An adhesive body dressing of the invention is produced on the laboratory. The hydrocolloid adhesive layer is produced as follows: 40 wt% polyacrylic acid; 26,5 wt% sodium carboxymethyl cellulose; 30 wt% purified water; 3 wt% glycerin; 0,15 wt% carbamide; 0,1 wt% aluminium glycinate, and 0,2 wt% dipotassium glycyrrhizate is stirred and hydrocolloid adhesive is obtained. A typical commercially available compostable film comprising polymers obtained from renewable biomass sources is supplied for a backing layer. The compostable film is made of material comprising polymers obtained from renewable biomass sources. The polymers comprise polylactic acid. The adhesive — body dressings are produced such that an additional adhesive layer made of a hot melt glue is provided on the backing layer. The hot melt glue is made of compostable materials and it comprises 18 wt% waxes, 64 wt% resins and 18 wt% polymers, based on the total weight of the composition. The adhesive layer has thickness of 0,3 mm.
Finally, the hydrocolloid adhesive layer having a 0,3 mm thickness is used to cover entire adhesive layer to provide an adhesive body dressing.
The adhesive body dressing was worn by the six volunteer test subjects for the purpose of determining its characteristics with duration of adhesion and general convenience. The adhesive body dressing was worn between 24 and 48 — hours by the test subjects.
N After a test adhesive body dressing was removed from a test subject,
N the results were evaluated on the basis of a multiple-choice guestionnaire.
S All test adhesive body dressing was remained on the skin until a test
N subject decided to detach a test adhesive body dressing.
E 30 None of the subjects reported an irritation on a skin. > The inventors surprisingly found out that an adhesive body dressing
N comprising a hydrocolloid adhesive layer having a 0,3 mm thickness and made of
O biodegradable or compostable material is more user friendly than an adhesive
S body dressing having a hydrocolloid adhesive layer comprising non- biodegradable substances. Furthermore, the inventors surprisingly found out that an adhesive body dressing having such hydrocolloid adhesive layer is able to prevent skin irritation caused by an additional adhesive layer comprising compounds which typically irritate skin. In other words, irritative compounds of the adhesive layer do not penetrate through the hydrocolloid adhesive layer made of biodegradable or compostable material.
Example 5
Adhesive body dressings are produced on the laboratory. The hydrocolloid adhesive layer is same as in example 3. — Films having thickness 35 pm and 20 um are supplied for a backing layer. The films are typical commercially available compostable films. The compostable films are made of material comprising polymers obtained from renewable biomass sources.
The polymers comprise polylactic acid.
Two adhesive body dressings are produced providing the hydrocolloid adhesive layer directly on the backing layer. Two adhesive body dressings are produced such that an additional adhesive layer made of a hot melt glue is provided on the backing layer and the hydrocolloid adhesive layer is provided on the adhesive layer.
The hot melt glue is made of compostable materials and it comprises 18 wt% waxes, 64 wt% resins and 18 wt% polymers, based on the total weight of the composition.
A flexibility test of the adhesive body dressings was conducted and results are shown in table 1. During the flexibility test the adhesive body dressings were stretched and 5 min after the stretching was analysed relative difference between dimension of the original adhesive body dressing and the adhesive body dressing
N after stretching. Smaller relative difference denotes that an adhesive body dressing
N adapts better on a human body. In other words, an adhesive body dressing
S conforms with body curves.
N
E Thickness of | Hot melt glue between the the hydrocolloid adhesive * backing hydrocolloid adhesive layer and | layer is directly provided on
N layer the backing layer the backing layer o
S
Table 1 Relative difference between dimension of the original adhesive body dressing and the adhesive body dressing after stretching
The inventors surprisingly found out that an additional adhesive layer between a hydrocolloid adhesive layer and a backing layer improves adaptation of an adhesive body dressing comprising backing layer made of biodegradable or compostable material comprising polymers obtained from renewable biomass sources.
The invention has been described above with reference to the examples and to the examples shown in the figures. However, the invention is in no way restricted to the above examples but may vary within the scope of the claims.
N
N
O
N
<
G
N
I a a
N
0
LÖ
N
N
O
N
Claims (17)
1. An adhesive body dressing (10) comprising a backing layer (B) and a hydrocolloid adhesive layer (H), the backing layer (B) is a film layer or a foam layer comprising a first side (B1) and a second side (B2), the hydrocolloid adhesive layer (H)is provided on the first side (B1) of backing layer (B), the backing layer (B) and the hydrocolloid adhesive layer (H) being made of biodegradable material, characterized inthat: - the backing layer (B) comprises a backing material layer (20) made of material comprising polymers derived from renewable biomass sources, and - the hydrocolloid adhesive layer (H) comprises a hydrocolloid material layer (30) made of a hydrocolloid adhesive composition comprising a thickening component and an absorbent component.
2. An adhesive body dressing (10) according to claim 1, characterized inthat: - the thickening component of the hydrocolloid adhesive composition is derived from renewable biomass sources; or - the thickening component of the hydrocolloid adhesive composition is derived from plant biomass; or - the thickening component of the hydrocolloid adhesive composition is derived from a polysaccharide comprising source; or - the thickening component of the hydrocolloid adhesive composition being a structural acidic heteropolysaccharide or a thickening component being a cellulose derivate; or «N 25 - the thickening component of the hydrocolloid adhesive composition O being pectic polysaccharides or the thickening component of the hydrocolloid + adhesive composition being carboxymethyl cellulose or the thickening component ? of the hydrocolloid adhesive composition is derived from carboxymethyl cellulose; = or E 30 - the thickening component of the hydrocolloid adhesive composition ” being carboxymethyl cellulose or the thickening component of the hydrocolloid N adhesive composition is derived from carboxymethyl cellulose; or - the thickening component of the hydrocolloid adhesive composition is S derived from natural cellulose; or - the thickening component of the hydrocolloid adhesive composition being a salt of carboxymethyl cellulose; or
- the thickening component of the hydrocolloid adhesive composition being sodium carboxymethyl cellulose.
3. An adhesive body dressing (10) according to claim 1 or 2, characterized inthat: - the absorbent component of the hydrocolloid adhesive composition being polymer; or - the absorbent component of the hydrocolloid adhesive composition being polyolefin; or - the absorbent component of the hydrocolloid adhesive composition being mucoadhesive polymer; or - the absorbent component of the hydrocolloid adhesive composition being polyacrylic acid.
4. An adhesive body dressing (10) according to any one of claims 1 to 3, characterized inthat: - the hydrocolloid adhesive composition comprising 10 - 80 wt% the thickening component and 20 - 90 wt% the absorbent component, based on the total weight of the composition; or - the hydrocolloid adhesive composition comprising 10 - 80 wt% the thickening component and 20 - 90 wt% the absorbent component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%; or -the hydrocolloid adhesive composition comprising 10 —- 50 wt% the thickening component obtained from a compound comprising polysaccharides, 20 N - 50 wt% the absorbent component, and 20 wt% - 35 wt% water component, N based on the total weight of the composition; or S - the hydrocolloid adhesive composition comprising 10 - 50 wt% the N thickening component obtained from a compound comprising polysaccharides, 20 I 30 - 50 wt% the absorbent component, and 20 wt% - 35 wt% water component, > based on the total weight of the composition, and with the proviso that components N of the hydrocolloid adhesive composition taken together adds up to 100 wt%; or O - the hydrocolloid adhesive composition comprising 10 - 50 wt% the S thickening component obtained from a compound comprising polysaccharides, 20 -50 wt% the absorbent component, and 27 wt% - 32 wt% water component, based on the total weight of the composition, and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
5.An adhesive body dressing (10) according to any one of claims 1 to 4, characterized inthat: - the hydrocolloid adhesive composition further comprising 1 wt% - 5 wt% glyserin component, based on the total weight of the composition; or - the hydrocolloid adhesive composition further comprising 1 wt% - 5 wt% glyserin component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken — together adds up to 100 wt%; or - the hydrocolloid adhesive composition further comprising 2 wt% - 4 wt% glyserin component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
6. An adhesive body dressing (10) according to any one of claims 1 to 5, characterized inthat: - the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,5 wt% carbamide component, based on the total weight of the composition; or - the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,25 wt% carbamide component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%; or - the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,15 wt% aluminium glycinate component, based on the total weight of the N composition; or N - the hydrocolloid adhesive composition further comprising 0,05 wt% S - 0,15 wt% aluminium glycinate component, based on the total weight of the N composition and with the proviso that components of the hydrocolloid adhesive I 30 composition taken together adds up to 100 wt%. > - the hydrocolloid adhesive composition further comprising 0,1 wt% - N 0,5 wt% carbamide component and 0,05 wt% - 0,15 wt% aluminium glycinate O component, based on the total weight of the composition and with the proviso that S components of the hydrocolloid adhesive composition taken together adds up to 100 wt%; or
- the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,5 wt% carbamide component and 0,05 wt% - 0,15 wt% aluminium glycinate component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
7.An adhesive body dressing (10) according to any one of claims 1 to 6, characterized inthat: - the hydrocolloid adhesive layer (H) having a first side (H1) and a second side (H2), the hydrocolloid adhesive layer (H) having a hydrocolloid adhesive layer thickness (HT) in a direction between the first side (H1) and the second side (H2), and the hydrocolloid adhesive layer thickness (HT) being more than 0,05 mm or more than 0,1 mm; or - the hydrocolloid adhesive layer (H) having a first side (H1) and a second side (H2), the hydrocolloid adhesive layer (H) having a hydrocolloid adhesive layer thickness (HT) in a direction between the first side (H1) and the second side (H2), and the hydrocolloid adhesive layer thickness (HT) being between 0,05 mm and 0,2mm; or - the hydrocolloid adhesive layer (H) having a first side (H1) and a second side (H2), the hydrocolloid adhesive layer (H) having a hydrocolloid adhesive layer thickness (HT) in a direction between the first side (H1) and the second side (H2), and the hydrocolloid adhesive layer thickness (HT) being between 0,1 mm and 10 mm; or - the hydrocolloid adhesive layer (H) having a first side (H1) and a N second side (H2), the hydrocolloid adhesive layer (H) having a hydrocolloid N adhesive layer thickness (HT) in a direction between the first side (H1) and the S second side (H2), and the hydrocolloid adhesive layer thickness (HT) being N between 0,2 mm and 5 mm; or E 30 - the hydrocolloid adhesive layer (H) having a first side (H1) and a > second side (H2), the hydrocolloid adhesive layer (H) having a hydrocolloid N adhesive layer thickness (HT) in a direction between the first side (H1) and the second side (H2), and the hydrocolloid adhesive layer thickness (HT) being O between 0,2 mm and 0,5 mm.
8. An adhesive body dressing (10) according to any one of claims 1 to 7, characterized inthat: - the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,3 wt% dipotassium glycyrrhizate component, based on the total weight of the composition; or - the hydrocolloid adhesive composition further comprising 0,1 wt% - 0,3 wt% dipotassium glycyrrhizate component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
9. An adhesive body dressing (10) according to any one of claims 1 to 8, characterized inthat: - the hydrocolloid adhesive composition comprises 35 wt% - 45 wt% the absorbent component, the absorbent component being polyacrylic acid, 20 wt% - 30 wt% the thickening component, the thickening component of the hydrocolloid adhesive composition being sodium carboxymethyl cellulose, 25 wt% - 35 wt% water component, and 2 wt% - 4 wt% glycerin, based on the total weight of the composition; or - the hydrocolloid adhesive composition comprises 35 wt% - 45 wt% — the absorbent component, the absorbent component being polyacrylic acid; 20 wt% - 30 wt% the thickening component, the thickening component of the hydrocolloid adhesive composition being sodium carboxymethyl cellulose; 25 wt% - 35 wt% water component;and 2 wt% - 4 wt% glycerin; based on the total weight of the composition and with the proviso that components of the N 25 hydrocolloid adhesive composition taken together adds up to 100 wt%. S N 10. An adhesive body dressing (10) according to any one of claims 1 to S 9,characterized inthatthe hydrocolloid adhesive composition comprises: N - 35 wt% - 45 wt% the absorbent component, the absorbent I 30 component being polyacrylic acid, > - 20 wt% - 30 wt% the thickening component, the thickening N component of the hydrocolloid adhesive layer (H) being sodium carboxymethyl O cellulose, S - 25 wt% - 35 wt% water component, - 2 wt% - 4 wt% glycerin component, - 0,1 wt% - 0,5 wt% carbamide component,
- 0,05 wt% - 0,15 wt% aluminium glycinate component, and - 0,1 wt% - 0,3 wt% dipotassium glycyrrhizate component, based on the total weight of the composition and with the proviso that components of the hydrocolloid adhesive composition taken together adds up to 100 wt%.
11. An adhesive body dressing (10) according to any one of claims 1 to 10, characterized inthat: - the backing layer (B) having a backing layer thickness (BT) in a direction between the first side (B1) and the second side (B2), and the backing layer thickness (BT) being between 10 um and 50 um; or - the backing layer (B) having a backing layer thickness (BT) in a direction between the first side (B1) and the second side (B2), and the backing layer thickness (BT) being between 20 um and 40 um.
12. An adhesive body dressing (10) according to any one of claims 1 to ll characterized in that: - the backing layer (B) is made of biodegradable material or compostable material comprising polyester; or - the backing layer (B) is made of biodegradable material or compostable material comprising aliphatic polyester; or - the backing layer (B) is made of compostable material comprising aliphatic polyester; or - the backing layer (B) made of compostable material comprising polylactic acid; or - the backing layer (B) made of compostable material comprising N polylactic acid 50 - 100 wt%, based on the total weight of the composition. N S 13. An adhesive body dressing (10) according to any one of claims 1 to N 12,characterized inthat: E 30 - the hydrocolloid adhesive layer (H) having a first side (H1) and a > second side (H2), the second side (H2) of the hydrocolloid adhesive layer (H) facing N towards the first side (B1) of the baking layer (B), and the adhesive body dressing O (10) comprises an additional adhesive layer (A) made of biodegradable material or S compostable material, the additional adhesive layer (A) is provided between the first side (B1) of the baking layer (B) and the second side (H2) of the hydrocolloid adhesive layer (H); or
-the hydrocolloid adhesive layer (H) having a first side (H1) and a second side (H2), the second side (H2) of the hydrocolloid adhesive layer (H) facing towards the first side (B1) of the baking layer (B), and the adhesive body dressing (10) comprises an additional adhesive layer (A), the additional adhesive layer (A)is provided between the first side (B1) of the baking layer (B) and the second side (HZ) of the hydrocolloid adhesive layer (H), and the additional adhesive layer (A) is made of an additional adhesive layer composition comprising waxes, resins and polymer, and the adhesive layer composition being biodegradable or compostable; or - the hydrocolloid adhesive layer (H) having a first side (H1) and a second side (H2), the second side (H2) of the hydrocolloid adhesive layer (H) facing towards the first side (B1) of the baking layer (B), and the adhesive body dressing (10) comprises an additional adhesive layer (A), the additional adhesive layer (A)is provided between the first side (B1) of the baking layer (B) and the second side — (HZ) of the hydrocolloid adhesive layer (H), and the additional adhesive layer (A) comprises an additional adhesive layer composition comprising 5 wt% - 30 wt% waxes, 40 wt% - 90 wt% resins and 5 wt% - 30 wt% polymer, based on the total weight of the composition, and the adhesive layer composition being biodegradable or compostable; or - the hydrocolloid adhesive layer (H) having a first side (H1) and a second side (H2), the second side (H2) of the hydrocolloid adhesive layer (H) facing towards the first side (B1) of the baking layer (B), and the adhesive body dressing (10) comprises an additional adhesive layer (A) comprises an additional adhesive layer composition, the additional adhesive layer (A) is provided between the first side (B1) of the baking layer (B) and the second side (H2) of the hydrocolloid N adhesive layer (H), and the adhesive layer composition comprises 5 wt% - 30 wt% N waxes, 40 wt% - 90 wt% resins and 5 wt% - 30 wt% polymer, based on the total S weight of the composition, and the adhesive layer composition being N biodegradable or compostable and with the proviso that components of the E 30 adhesive layer composition taken together adds up to 100 wt%. a N 14. An adhesive body dressing (10) according to any one of claims 1 to O 13,characterized inthat: S - a hydrocolloid adhesive layer (H) having a first side (H1) and a second — side (H2), the second side (H2) of the hydrocolloid adhesive layer (H) is provided on the first side (B1) of the baking layer (B), the adhesive body dressing (10)
comprises a first removable covering layer (CF) provided on the first side (H1) of hydrocolloid adhesive layer (H), and the first removable covering layer (CF) is made of biodegradable material or compostable material; or - a hydrocolloid adhesive layer (H) having a first side (H1) and a second — side (H2), the second side (H2) of the hydrocolloid adhesive layer (H) is provided on the first side (B1) of the baking layer (B), the adhesive body dressing (10) comprises a first removable covering layer (CF) provided on the second side (B2) of the baking layer (B), and the second removable covering layer (CF) is made of biodegradable material or compostable material; or - a hydrocolloid adhesive layer (H) having a first side (H1) and a second side (H2), the second side (H2) of the hydrocolloid adhesive layer (H) is provided on the first side (B1) of the baking layer (B), the adhesive body dressing (10) comprises a first removable covering layer (CF) provided on the first side (H1) of hydrocolloid adhesive layer (H), and the first removable covering layer (CF) is made of biodegradable material or compostable material, the adhesive body dressing (10) comprises a second removable covering layer (CS) provided on the second side (B2) of the baking layer (B), and the second removable covering layer (CS) is made of biodegradable material or compostable material.
15. A method for manufacturing an adhesive body dressing (10) having a hydrocolloid adhesive layer (H) and a backing layer (B), characterized in that the method comprises: - forming a backing layer (B) of a biodegradable material comprising polymers derived from renewable biomass sources; and - providing an adhesive hydrocolloid layer (H) on the backing layer (B), N the adhesive hydrocolloid layer being made of biodegradable hydrocolloid N adhesive composition comprising a thickening component and absorbent S component of the hydrocolloid adhesive layer (H). N I 30
16. A method according to claim 15, characterized in that the > method comprises. N - providing an additional adhesive layer between the backing layer (B) O and the adhesive hydrocolloid layer (H). 3
17. Amethod according to claim 15 or 16, characterized inthat the adhesive body dressing (10) being an adhesive body dressing (10) according to any one claims 1 to 14.
N N O N < O N TT I oc a N 0 LÖ N N O N
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20225321A FI130968B1 (en) | 2022-04-12 | 2022-04-12 | An adhesive body dressing and a method for manufacturing an adhesive body dressing |
| PCT/FI2023/050198 WO2023198959A1 (en) | 2022-04-12 | 2023-04-11 | An adhesive body dressing and a method for manufacturing an adhesive body dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20225321A FI130968B1 (en) | 2022-04-12 | 2022-04-12 | An adhesive body dressing and a method for manufacturing an adhesive body dressing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI20225321A1 true FI20225321A1 (en) | 2023-10-13 |
| FI130968B1 FI130968B1 (en) | 2024-06-20 |
Family
ID=88244261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20225321A FI130968B1 (en) | 2022-04-12 | 2022-04-12 | An adhesive body dressing and a method for manufacturing an adhesive body dressing |
Country Status (2)
| Country | Link |
|---|---|
| FI (1) | FI130968B1 (en) |
| WO (1) | WO2023198959A1 (en) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK169711B1 (en) * | 1993-01-15 | 1995-01-23 | Coloplast As | A dressing |
| US6825246B1 (en) * | 1998-11-03 | 2004-11-30 | Bristol-Myers Squibb Company | Hydrocolloid adhesive compositions |
| CN1279894C (en) * | 2000-09-14 | 2006-10-18 | 久光医药股份有限公司 | Preparations for coating wound |
| US20050137512A1 (en) * | 2003-12-23 | 2005-06-23 | Campbell Todd D. | Wound dressing and method for controlling severe, life-threatening bleeding |
| JP4398158B2 (en) * | 2002-10-03 | 2010-01-13 | 久光製薬株式会社 | Patch |
| CA2636106C (en) * | 2006-01-18 | 2014-05-27 | Coloplast A/S | Layered adhesive construction with adhesive layers having different hydrocolloid composition |
| KR101178435B1 (en) * | 2010-04-14 | 2012-08-30 | 김봉조 | Water-Containing Adhesive Gel Sheet |
| CN105833331B (en) * | 2016-05-20 | 2019-03-19 | 华熙福瑞达生物医药有限公司 | A kind of preparation method and products obtained therefrom of degradable biological wound dressing |
| FI20205047A1 (en) * | 2020-01-17 | 2021-07-18 | Dermeco Oy | An adhesive body dressing and method for manufacturing an adhesive body dressing |
-
2022
- 2022-04-12 FI FI20225321A patent/FI130968B1/en active
-
2023
- 2023-04-11 WO PCT/FI2023/050198 patent/WO2023198959A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI130968B1 (en) | 2024-06-20 |
| WO2023198959A1 (en) | 2023-10-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108014366B (en) | Marine biological material composite hydrogel dressing and preparation method thereof | |
| EP3790599B1 (en) | Wound dressing for treatment of damaged skin | |
| US4655758A (en) | Microbial polysaccharide articles and methods of production | |
| JP4606586B2 (en) | Functional chitosan derivatives | |
| El-Wakil et al. | Bacterial cellulose/phytochemical’s extracts biocomposites for potential active wound dressings | |
| Namviriyachote et al. | Polyurethane-biomacromolecule combined foam dressing containing asiaticoside: fabrication, characterization and clinical efficacy for traumatic dermal wound treatment | |
| US20050203058A1 (en) | Compositions of alpha- and beta-chitosan and methods of preparing them | |
| KR20080018360A (en) | A wound-healing dressing patch with hydrogel layer containing chitosan | |
| AU2021208613B2 (en) | An adhesive body dressing and method for manufacturing an adhesive body dressing | |
| US8303980B2 (en) | Wound-dressing material and method for manufacturing the same | |
| Chen et al. | Mechanical properties and wound healing potential of bacterial cellulose-xyloglucan-dextran hydrogels | |
| FI130411B (en) | An adhesive body dressing and a method for manufacturing an adhesive body dressing | |
| FI20225321A1 (en) | An adhesive body dressing and a method for manufacturing an adhesive body dressing | |
| Zhang et al. | Lignin-containing hydrogels: Transforming a low-value byproduct to absorbents, wound dressings and strain sensors | |
| KR101413510B1 (en) | Method of preparing raw materials for transplantation using biocompatible polymers | |
| CN115887747B (en) | Liquid wound protection material containing nano-pore flexible membrane and preparation method thereof | |
| Bhatnagar et al. | Wound dressings from algal polymers | |
| CN104069535A (en) | Preparation method and application of bioactive composite film hemostasis dressing | |
| GB2409974A (en) | Gel comprising citrus complex carbohydrates for the application to a wound | |
| Srimai et al. | Enhancement of Poly (vinyl alcohol) hydrogel properties by N-Succinyl chitosan and Mesona chinensis extract for use as wound dressings | |
| WO2018167622A1 (en) | Process for the preparation of wound dressing sponge | |
| KR102459823B1 (en) | biodegradable sanitary pads | |
| CN106512074A (en) | Polyelectrolyte sponge dressing | |
| Diem et al. | Research Article Sugarcane Bagasse-Derived Cellulose Nanocrystal/Polyvinyl Alcohol/Gum Tragacanth Composite Film Incorporated with Betel Leaf Extract as a Versatile Biomaterial for Wound Dressing | |
| CA1295327C (en) | Pliant, water-absorbent, laminar mass of microbial cellulose |