FI20012082A0 - Biologically active peptides for the correction of nerve damage - Google Patents

Biologically active peptides for the correction of nerve damage

Info

Publication number
FI20012082A0
FI20012082A0 FI20012082A FI20012082A FI20012082A0 FI 20012082 A0 FI20012082 A0 FI 20012082A0 FI 20012082 A FI20012082 A FI 20012082A FI 20012082 A FI20012082 A FI 20012082A FI 20012082 A0 FI20012082 A0 FI 20012082A0
Authority
FI
Finland
Prior art keywords
biologically active
correction
active peptides
nerve damage
laminin
Prior art date
Application number
FI20012082A
Other languages
Finnish (fi)
Swedish (sv)
Inventor
Paeivi Liesi
Original Assignee
Paeivi Liesi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paeivi Liesi filed Critical Paeivi Liesi
Priority to FI20012082A priority Critical patent/FI20012082A0/en
Publication of FI20012082A0 publication Critical patent/FI20012082A0/en
Priority to PCT/FI2002/000831 priority patent/WO2003035675A1/en
Priority to AT02770017T priority patent/ATE490972T1/en
Priority to CA2465245A priority patent/CA2465245C/en
Priority to US10/492,850 priority patent/US20040266991A1/en
Priority to AU2002336124A priority patent/AU2002336124B2/en
Priority to JP2003538188A priority patent/JP4312054B2/en
Priority to EP02770017A priority patent/EP1438329B1/en
Priority to DE60238551T priority patent/DE60238551D1/en
Priority to DK02770017.8T priority patent/DK1438329T3/en
Priority to US11/127,206 priority patent/US7659255B2/en
Priority to US12/141,129 priority patent/US7741436B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

The present invention relates to biologically active peptides derived from the neurite outgrowth-promoting domain of laminin-1, i.e. the γ1-chain of laminin-1. These peptides include the decapeptide RDIAEIIKDI (SEQ ID NO: 1) and the truncated peptides derived therefrom comprising the biologically active domain thereof, the tripeptide KDI. The invention is directed to the biologically active tripeptide motif KDI, and to its use in promoting regeneration of neuronal or non-neuronal tissues and, in specific, to its use in the treatment of spinal cord injuries.
FI20012082A 2001-10-26 2001-10-26 Biologically active peptides for the correction of nerve damage FI20012082A0 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FI20012082A FI20012082A0 (en) 2001-10-26 2001-10-26 Biologically active peptides for the correction of nerve damage
DK02770017.8T DK1438329T3 (en) 2001-10-26 2002-10-25 Biologically active peptides and their use in repairing damaged nerves
US10/492,850 US20040266991A1 (en) 2001-10-26 2002-10-25 Biologically active peptides and their use for repairing injured nerves
AT02770017T ATE490972T1 (en) 2001-10-26 2002-10-25 BIOLOGICALLY ACTIVE PEPTIDES AND THEIR USE FOR REPAIRING INJURED NERVES
CA2465245A CA2465245C (en) 2001-10-26 2002-10-25 Biologically active peptides and their use for repairing injured nerves
PCT/FI2002/000831 WO2003035675A1 (en) 2001-10-26 2002-10-25 Biologically active peptides and their use for repairing injured nerves
AU2002336124A AU2002336124B2 (en) 2001-10-26 2002-10-25 Biologically active peptides and their use for repairing injured nerves
JP2003538188A JP4312054B2 (en) 2001-10-26 2002-10-25 Biologically active peptides and repair of damaged nerves using the same
EP02770017A EP1438329B1 (en) 2001-10-26 2002-10-25 Biologically active peptides and their use for repairing injured nerves
DE60238551T DE60238551D1 (en) 2001-10-26 2002-10-25 BIOLOGICALLY ACTIVE PEPTIDES AND THEIR USE FOR THE REPAIR OF NERVES INJURED
US11/127,206 US7659255B2 (en) 2001-10-26 2005-05-12 Methods of inhibiting glutamate receptors by administering the tripeptide KDI
US12/141,129 US7741436B2 (en) 2001-10-26 2008-06-18 Biologically active peptides and their use for repairing injured nerves

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20012082A FI20012082A0 (en) 2001-10-26 2001-10-26 Biologically active peptides for the correction of nerve damage

Publications (1)

Publication Number Publication Date
FI20012082A0 true FI20012082A0 (en) 2001-10-26

Family

ID=8562134

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20012082A FI20012082A0 (en) 2001-10-26 2001-10-26 Biologically active peptides for the correction of nerve damage

Country Status (10)

Country Link
US (3) US20040266991A1 (en)
EP (1) EP1438329B1 (en)
JP (1) JP4312054B2 (en)
AT (1) ATE490972T1 (en)
AU (1) AU2002336124B2 (en)
CA (1) CA2465245C (en)
DE (1) DE60238551D1 (en)
DK (1) DK1438329T3 (en)
FI (1) FI20012082A0 (en)
WO (1) WO2003035675A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005029468A1 (en) * 2005-06-24 2006-12-28 Plt Patent & Licence Trading Ltd. Use of an exogenous or endogenous inhibitor of N-methyltransferase for the manufacture of a medicament for therapy and prophylaxis of Parkinson's syndrome
RU2301678C1 (en) * 2006-05-30 2007-06-27 Общество С Ограниченной Ответственностью "Сиа Пептайдс" Peptide stimulating regeneration of central nervous system neurons, pharmaceutical composition based on thereof and method for its using
CA2692926A1 (en) * 2007-05-31 2008-12-11 The Hertz Corporation System and method for automatically generating an airplane boarding pass for a traveler returning a rental car
US8008253B2 (en) * 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
WO2009114539A2 (en) * 2008-03-10 2009-09-17 University Of Louisville Research Foundation Neuroprotective integrin-binding peptide and angiopoietin-1 treatments
GB201700529D0 (en) * 2017-01-12 2017-03-01 Rogers April Laminin receptor peptide

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT276041B (en) * 1968-08-16 1969-11-10 Dragoco Gerberding Co Gmbh Process for the production of a concentrated, practically sterile raw onion aroma
US3590722A (en) * 1969-06-09 1971-07-06 Samuel Leptrone Flavor injector device
HU185263B (en) 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
FI922517A (en) * 1992-05-29 1993-11-30 Paeivi Liesi NERVREPARERINGSMEDEL OCH DESS ANVAENDNING
GB9217316D0 (en) 1992-08-14 1992-09-30 Ludwig Inst Cancer Res Schwann cell mitogenic factor,its preparation and use
GB9324473D0 (en) 1993-11-29 1994-01-12 Oxford Res Support Co Ltd Isolation of streptokinase by affinity chromatography
EP0783253B1 (en) * 1995-07-26 2002-10-23 Firmenich Sa Flavoured products and method for preparing same
US5721256A (en) * 1997-02-12 1998-02-24 Gpi Nil Holdings, Inc. Method of using neurotrophic sulfonamide compounds
US20020168718A1 (en) * 1997-04-03 2002-11-14 California Institute Of Technology Enzyme-mediated modification of fibrin for tissue engineering
AU7245598A (en) 1997-04-03 1998-10-22 California Institute Of Technology Enzyme-mediated modification of fibrin for tissue engineering
US6075119A (en) * 1997-04-07 2000-06-13 The Rockefeller University Peptides useful for reducing symptoms of toxic shock syndrome
IL121191A0 (en) * 1997-06-29 1997-11-20 Yeda Res & Dev Synthetic peptides and pharmaceutical compositions comprising them
MXPA01010692A (en) 1999-04-22 2004-09-06 Univ Zuerich Modified protein matrices.
DE20010297U1 (en) 2000-06-08 2000-08-31 Eth Zuerich Zuerich Enzyme-mediated modification of fibrin for tissue manipulation: fibrin formulations with peptides

Also Published As

Publication number Publication date
CA2465245A1 (en) 2003-05-01
US7659255B2 (en) 2010-02-09
EP1438329B1 (en) 2010-12-08
US20080249021A1 (en) 2008-10-09
US20040266991A1 (en) 2004-12-30
US20050288231A1 (en) 2005-12-29
DK1438329T3 (en) 2011-03-28
WO2003035675A1 (en) 2003-05-01
EP1438329A1 (en) 2004-07-21
JP2005512979A (en) 2005-05-12
JP4312054B2 (en) 2009-08-12
AU2002336124B2 (en) 2008-07-03
DE60238551D1 (en) 2011-01-20
ATE490972T1 (en) 2010-12-15
CA2465245C (en) 2012-09-11
US7741436B2 (en) 2010-06-22

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