FI111342B - Syntetisatoranläggning - Google Patents

Syntetisatoranläggning Download PDF

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Publication number
FI111342B
FI111342B FI991175A FI991175A FI111342B FI 111342 B FI111342 B FI 111342B FI 991175 A FI991175 A FI 991175A FI 991175 A FI991175 A FI 991175A FI 111342 B FI111342 B FI 111342B
Authority
FI
Finland
Prior art keywords
synthesizer
module
unit
synthesis
plant according
Prior art date
Application number
FI991175A
Other languages
English (en)
Finnish (fi)
Other versions
FI991175A (sv
FI991175A0 (sv
Inventor
Antti P Manninen
Original Assignee
Pam Solutions Ltd Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pam Solutions Ltd Oy filed Critical Pam Solutions Ltd Oy
Priority to FI991175A priority Critical patent/FI111342B/sv
Publication of FI991175A0 publication Critical patent/FI991175A0/sv
Priority to PCT/FI2000/000468 priority patent/WO2000071242A1/en
Priority to AU47602/00A priority patent/AU4760200A/en
Publication of FI991175A publication Critical patent/FI991175A/sv
Application granted granted Critical
Publication of FI111342B publication Critical patent/FI111342B/sv

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B01J19/004—Multifunctional apparatus for automatic manufacturing of various chemical products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00018—Construction aspects
    • B01J2219/0002—Plants assembled from modules joined together
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00281—Individual reactor vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00479—Means for mixing reactants or products in the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00495—Means for heating or cooling the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00599—Solution-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00689—Automatic using computers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00695—Synthesis control routines, e.g. using computer programs
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (5)

1. Syntetisatoranläggning som omfattar en dator (9) eller motsvarande för styrning av kemiska synteser och den egentliga syntetisatorn (8) för att ästadkomma och 5 genomföra en önskad kemisk reaktion, kännetecknad av att syntetisatorn (8) är uppdelad i en fast grundenhet eller -modul (1) med medel (3, 4, 5) för att utföra basfunktioner, säsom förtemperaturreglering, behandling av reagenser, säsom för utspädningar, tillsatser och överföringar, samt en förbindelse tili datoranordningen (9), som innehaller ett program, och tili en separat, utbytbar tilläggsenhet eller -10 modul (2) som innehaller medel (6, 7), säsom den egentliga reaktom och dess tilläggsutrustning, säsom en blandare, kylare, tömnings- eller nägon annan ventil aller andra nödvändiga hjälpanordningar, för att utföra reaktioner beroende av eaktionen som skall utföras.
2. Syntetisatoranläggning eniigt patentkrav 1, kännetecknad av att grundmodulen (1) innehaller medel tili exempel förtemperaturreglering, tillsats och utspädning av reagenser, en datorförbindelse och beredskaper för montering av tilläggsanordningar.
3. Syntetisatoranläggning eniigt patentkrav 1, kännetecknad av att den dessutom innehäller ett program, särskilt ett receptbaserat program, för användning av en eller flera anordningar.
4. Syntetisatoranläggning eniigt patentkrav 1, kännetecknad av att 25 tilläggsmodulen (2) är i form av en utbytbar reaktionspanel som innehäller de varierande komponenter som behövs för ifrägavarande syntes.
5. Syntetisatoranläggning eniigt nägot av föregäende patentkrav, kännetecknad av att det finns en eller flera syntetisatorer (8) kopplade tili datorenheten och att 30 en eller flera av dem kan användas för att utföra samma syntes eller att varje syntesenhet kan användas för att utföra en egen uppgift som en separat enhet. BNSDOCID: <FI 111342B1 I >
FI991175A 1999-05-24 1999-05-24 Syntetisatoranläggning FI111342B (sv)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FI991175A FI111342B (sv) 1999-05-24 1999-05-24 Syntetisatoranläggning
PCT/FI2000/000468 WO2000071242A1 (en) 1999-05-24 2000-05-24 Synthesizer apparatus
AU47602/00A AU4760200A (en) 1999-05-24 2000-05-24 Synthesizer apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI991175A FI111342B (sv) 1999-05-24 1999-05-24 Syntetisatoranläggning
FI991175 1999-05-24

Publications (3)

Publication Number Publication Date
FI991175A0 FI991175A0 (sv) 1999-05-24
FI991175A FI991175A (sv) 2000-11-25
FI111342B true FI111342B (sv) 2003-07-15

Family

ID=8554721

Family Applications (1)

Application Number Title Priority Date Filing Date
FI991175A FI111342B (sv) 1999-05-24 1999-05-24 Syntetisatoranläggning

Country Status (3)

Country Link
AU (1) AU4760200A (sv)
FI (1) FI111342B (sv)
WO (1) WO2000071242A1 (sv)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362699A (en) * 1981-03-10 1982-12-07 Bio Research, Inc. Apparatus for high pressure peptide synthesis
US4483964A (en) * 1983-06-20 1984-11-20 Chiron Corporation Reactor system and method for polynucleotide synthesis
US5580523A (en) * 1994-04-01 1996-12-03 Bard; Allen J. Integrated chemical synthesizers

Also Published As

Publication number Publication date
AU4760200A (en) 2000-12-12
FI991175A (sv) 2000-11-25
FI991175A0 (sv) 1999-05-24
WO2000071242A1 (en) 2000-11-30

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