FI101625B1 - Complex Suitable for Implementing a Procedure for Purification of Pre-S Hepatitis B Virus Surface Antigen - Google Patents

Complex Suitable for Implementing a Procedure for Purification of Pre-S Hepatitis B Virus Surface Antigen

Info

Publication number
FI101625B1
FI101625B1 FI904412A FI904412A FI101625B1 FI 101625 B1 FI101625 B1 FI 101625B1 FI 904412 A FI904412 A FI 904412A FI 904412 A FI904412 A FI 904412A FI 101625 B1 FI101625 B1 FI 101625B1
Authority
FI
Finland
Prior art keywords
hepatitis
surface antigen
virus surface
purification
implementing
Prior art date
Application number
FI904412A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI904412A0 (en
FI101625B (en
Inventor
Johann Eibl
Friedrich Dorner
Artur Mitterer
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of FI904412A0 publication Critical patent/FI904412A0/en
Application granted granted Critical
Publication of FI101625B publication Critical patent/FI101625B/en
Publication of FI101625B1 publication Critical patent/FI101625B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to a complex consisting of an insoluble polymeric support to which monomeric human albumin is covalently bonded, and of a pre-S hepatitis B virus surface antigen which is bound via its pre-S(2) and/or pre-S(1) part to the monomeric human albumin in a form which can be eluted. This complex can be used for therapeutic and diagnostic purposes and allows rapid and efficient purification of pre-S HBsAg by affinity chromatography.
FI904412A 1989-09-20 1990-09-07 Complex Suitable for Implementing a Procedure for Purification of Pre-S Hepatitis B Virus Surface Antigen FI101625B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT219889 1989-09-20
AT2198/89A AT392417B (en) 1989-09-20 1989-09-20 COMPLEXLY SUITABLE FOR PERFORMING A METHOD FOR CLEANING PRE-S-HEPATITIS-B-VIRUS SURFACE ANTIGENS

Publications (3)

Publication Number Publication Date
FI904412A0 FI904412A0 (en) 1990-09-07
FI101625B FI101625B (en) 1998-07-31
FI101625B1 true FI101625B1 (en) 1998-07-31

Family

ID=3529817

Family Applications (1)

Application Number Title Priority Date Filing Date
FI904412A FI101625B1 (en) 1989-09-20 1990-09-07 Complex Suitable for Implementing a Procedure for Purification of Pre-S Hepatitis B Virus Surface Antigen

Country Status (9)

Country Link
EP (1) EP0419446B1 (en)
JP (1) JP2721033B2 (en)
AT (2) AT392417B (en)
CA (1) CA2025263A1 (en)
DE (1) DE59008927D1 (en)
DK (1) DK0419446T3 (en)
ES (1) ES2074558T3 (en)
FI (1) FI101625B1 (en)
NO (1) NO300421B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111659355B (en) * 2020-06-23 2022-12-13 武汉瑞法医疗器械有限公司 Alkylation modified hepatitis B virus immunoadsorbent and preparation method thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL45247A0 (en) * 1974-07-11 1974-10-22 Yeda Res & Dev Water insoluble protein preparations
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen
ATE73349T1 (en) * 1984-06-18 1992-03-15 Chiron Corp HEPATITIS SURFACE ANTIGEN PARTICLE VACCINATION.
JPS6137738A (en) * 1984-07-31 1986-02-22 Tetsuo Nakamura Vaccine for hepatitis b
EP0243103B1 (en) * 1986-04-25 1992-12-30 Merck & Co. Inc. Purification of pre-s hbsag by polymerized serum albumin affinity binding
US4855055A (en) * 1988-09-28 1989-08-08 National Science Council Isolation and purification pre-S2 containing hepatitis B virus surface antigen by chemical affinity chromatography

Also Published As

Publication number Publication date
NO904085D0 (en) 1990-09-19
FI904412A0 (en) 1990-09-07
FI101625B (en) 1998-07-31
EP0419446A1 (en) 1991-03-27
DK0419446T3 (en) 1995-08-28
JPH03120300A (en) 1991-05-22
NO300421B1 (en) 1997-05-26
AT392417B (en) 1991-03-25
DE59008927D1 (en) 1995-05-24
ES2074558T3 (en) 1995-09-16
ATA219889A (en) 1990-09-15
EP0419446B1 (en) 1995-04-19
CA2025263A1 (en) 1991-03-21
NO904085L (en) 1991-03-21
ATE121417T1 (en) 1995-05-15
JP2721033B2 (en) 1998-03-04

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: IMMUNO AKTIENGESELLSCHAFT

MA Patent expired