ES8802250A1 - Un metodo para producir factor de necrosis de tumores. - Google Patents
Un metodo para producir factor de necrosis de tumores.Info
- Publication number
- ES8802250A1 ES8802250A1 ES544843A ES544843A ES8802250A1 ES 8802250 A1 ES8802250 A1 ES 8802250A1 ES 544843 A ES544843 A ES 544843A ES 544843 A ES544843 A ES 544843A ES 8802250 A1 ES8802250 A1 ES 8802250A1
- Authority
- ES
- Spain
- Prior art keywords
- necrosis factor
- tumour necrosis
- codes
- obtaining dna
- recombinant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE OBTIENE UN FACTOR DE NECROSIS, CULTIVANDO UNA CELULA RECOMBINANTE TRANSFORMADA CON UN ADN, QUE PUEDE ESTAR EN UN VECTOR REPLICABLE TAL COMO UN PLASMIDO O UN VIRUS, EL CUAL CODIFICA DICHO FACTOR JUNTO CON OTRO POLIPEPTIDO, COMO UNA SECUENCIA DELANTERA HETEROLOGA, POR EJEMPLO: LA SECUENCIA ENTEROTOXINA ST II DE E. COLI. DICHO FACTOR DE NECROSIS DE TUMORES, PUEDE SER HUMANO O NO, Y RESULTA DE LA SUPRESION, INSERCION O SUSTITUCION DE AMINOACIDOS EN LA PROTEINA (I). POSTERIORMENTE, SE PERMITE LA ACUMULACION DEL FACTOR EN EL CULTIVO Y FINALMENTE SE RECUPERA. ESTOS FACTORES O LINFOQUINAS, SE EMPLEAN EN EL TRATAMIENTO DE TUMORES MALIGNOS, SOLOS O EN SINERGIA CON UN INTERFERON.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62795984A | 1984-07-05 | 1984-07-05 | |
US62805984A | 1984-07-05 | 1984-07-05 | |
US62806084A | 1984-07-05 | 1984-07-05 | |
US67745484A | 1984-12-03 | 1984-12-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8802250A1 true ES8802250A1 (es) | 1988-05-01 |
ES544843A0 ES544843A0 (es) | 1988-05-01 |
Family
ID=27505180
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544843A Expired ES8802250A1 (es) | 1984-07-05 | 1985-07-03 | Un metodo para producir factor de necrosis de tumores. |
ES557105A Expired ES8800984A1 (es) | 1984-07-05 | 1986-10-01 | Un metodo para obtener adn que codifica factor de necrosis de tumores mutante |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557105A Expired ES8800984A1 (es) | 1984-07-05 | 1986-10-01 | Un metodo para obtener adn que codifica factor de necrosis de tumores mutante |
Country Status (1)
Country | Link |
---|---|
ES (2) | ES8802250A1 (es) |
-
1985
- 1985-07-03 ES ES544843A patent/ES8802250A1/es not_active Expired
-
1986
- 1986-10-01 ES ES557105A patent/ES8800984A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES8800984A1 (es) | 1987-12-16 |
ES557105A0 (es) | 1987-12-16 |
ES544843A0 (es) | 1988-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SPCF | Request for supplementary protection certificate filed |
Free format text: TASONERMIN: FACTOR DE NECROSIS TUMORAL ALFA-1A (BEROMUN) Spc suppl protection certif: C9900037 Filing date: 19991013 |
|
SPCG | Supplementary protection certificate granted |
Free format text: TASONERMIN: FACTOR DE NECROSIS TUMORAL ALFA-1A (BEROMUN) Spc suppl protection certif: C9900037 Filing date: 19991013 Expiry date: 20130222 Effective date: 20031029 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20151230 |