ES8802250A1 - Un metodo para producir factor de necrosis de tumores. - Google Patents

Un metodo para producir factor de necrosis de tumores.

Info

Publication number
ES8802250A1
ES8802250A1 ES544843A ES544843A ES8802250A1 ES 8802250 A1 ES8802250 A1 ES 8802250A1 ES 544843 A ES544843 A ES 544843A ES 544843 A ES544843 A ES 544843A ES 8802250 A1 ES8802250 A1 ES 8802250A1
Authority
ES
Spain
Prior art keywords
necrosis factor
tumour necrosis
codes
obtaining dna
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544843A
Other languages
English (en)
Other versions
ES544843A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ES8802250A1 publication Critical patent/ES8802250A1/es
Publication of ES544843A0 publication Critical patent/ES544843A0/es
Expired legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE OBTIENE UN FACTOR DE NECROSIS, CULTIVANDO UNA CELULA RECOMBINANTE TRANSFORMADA CON UN ADN, QUE PUEDE ESTAR EN UN VECTOR REPLICABLE TAL COMO UN PLASMIDO O UN VIRUS, EL CUAL CODIFICA DICHO FACTOR JUNTO CON OTRO POLIPEPTIDO, COMO UNA SECUENCIA DELANTERA HETEROLOGA, POR EJEMPLO: LA SECUENCIA ENTEROTOXINA ST II DE E. COLI. DICHO FACTOR DE NECROSIS DE TUMORES, PUEDE SER HUMANO O NO, Y RESULTA DE LA SUPRESION, INSERCION O SUSTITUCION DE AMINOACIDOS EN LA PROTEINA (I). POSTERIORMENTE, SE PERMITE LA ACUMULACION DEL FACTOR EN EL CULTIVO Y FINALMENTE SE RECUPERA. ESTOS FACTORES O LINFOQUINAS, SE EMPLEAN EN EL TRATAMIENTO DE TUMORES MALIGNOS, SOLOS O EN SINERGIA CON UN INTERFERON.
ES544843A 1984-07-05 1985-07-03 Un metodo para producir factor de necrosis de tumores. Expired ES8802250A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US62795984A 1984-07-05 1984-07-05
US62805984A 1984-07-05 1984-07-05
US62806084A 1984-07-05 1984-07-05
US67745484A 1984-12-03 1984-12-03

Publications (2)

Publication Number Publication Date
ES8802250A1 true ES8802250A1 (es) 1988-05-01
ES544843A0 ES544843A0 (es) 1988-05-01

Family

ID=27505180

Family Applications (2)

Application Number Title Priority Date Filing Date
ES544843A Expired ES8802250A1 (es) 1984-07-05 1985-07-03 Un metodo para producir factor de necrosis de tumores.
ES557105A Expired ES8800984A1 (es) 1984-07-05 1986-10-01 Un metodo para obtener adn que codifica factor de necrosis de tumores mutante

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557105A Expired ES8800984A1 (es) 1984-07-05 1986-10-01 Un metodo para obtener adn que codifica factor de necrosis de tumores mutante

Country Status (1)

Country Link
ES (2) ES8802250A1 (es)

Also Published As

Publication number Publication date
ES8800984A1 (es) 1987-12-16
ES557105A0 (es) 1987-12-16
ES544843A0 (es) 1988-05-01

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Legal Events

Date Code Title Description
SPCF Request for supplementary protection certificate filed

Free format text: TASONERMIN: FACTOR DE NECROSIS TUMORAL ALFA-1A (BEROMUN)

Spc suppl protection certif: C9900037

Filing date: 19991013

SPCG Supplementary protection certificate granted

Free format text: TASONERMIN: FACTOR DE NECROSIS TUMORAL ALFA-1A (BEROMUN)

Spc suppl protection certif: C9900037

Filing date: 19991013

Expiry date: 20130222

Effective date: 20031029

FD2A Announcement of lapse in spain

Effective date: 20151230