Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
METODO DE PREPARAR ACIDOS PIRAZOL-4-ACETICOS SUSTITUIDOS. CONSISTE EN HIDROLIZAR LOS NITRILOS DE LOS ACIDOS CARBOXILICOS DE FORMULA (I), EN UN MEDIO NEUTRO, ACIDO O ALCALINO, A TEMPERATURA ELEVADA Y EN PRESENCIA DE UN DISOLVENTE, Y, CUANDO SE DESEE, SUS SALES CON BASES FARMACEUTICAMENTE COMPATIBLES SE OBTIENEN A PARTIR DE LOS ACIDOS LIBRES POR NEUTRALIZACION O A PARTIR DE SALES FACILMENTE SOLUBLES MEDIANTE DOBLE REACCION, SIENDO R1, R2 Y R3, IGUALES O DIFERENTES, CADA UNO UN ATOMO DE H O UN GRUPO ARILO, EVENTUALMENTE SUSTITUIDO, CON HASTA 12 ATOMOS DE CARBONO Y OTROS. TIENEN PROPIEDADES ANTIFLOGISTICAS, ANALGESICAS Y ANTIPIRETICAS.
ES556114A1986-06-171986-06-17Procedimiento para preparar acidos pirazol-4-aceticos substituidos
GrantedES556114A0
(es)