ES8708184A1 - Un metodo para preparar una vacuna polivalente de klebsiella inmunogenica - Google Patents

Un metodo para preparar una vacuna polivalente de klebsiella inmunogenica

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Publication number
ES8708184A1
ES8708184A1 ES553858A ES553858A ES8708184A1 ES 8708184 A1 ES8708184 A1 ES 8708184A1 ES 553858 A ES553858 A ES 553858A ES 553858 A ES553858 A ES 553858A ES 8708184 A1 ES8708184 A1 ES 8708184A1
Authority
ES
Spain
Prior art keywords
klebsiella
immunogenic
poly
valent vaccine
serotypes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES553858A
Other languages
English (en)
Other versions
ES553858A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Schweiz Serum und Impfinstitut Bern
Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweiz Serum und Impfinstitut Bern, Schweiz Serum und Impfinstitut und Institut zur Erforschung der Infektionskrankheiten filed Critical Schweiz Serum und Impfinstitut Bern
Priority to ES553858A priority Critical patent/ES8708184A1/es
Publication of ES553858A0 publication Critical patent/ES553858A0/es
Publication of ES8708184A1 publication Critical patent/ES8708184A1/es
Expired legal-status Critical Current

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

METODO PARA PREPARAR UNA VACUNA POLIVALENTE DE KLEBSIELLA. COMPRENDE: A) OBTENER UNA MEZCLA DE POLISACARIDOS CAPSULARES RELATIVAMENTE PUROS DE BACTERIAS KLEBSIELLA DE LOS SEROTIPOS 2,3,5,9,10,15,16,17,18,21,22,25,28,30,35,43,52,53,55,80,61,62,63 Y 64 MEDIANTE CULTIVO DE DICHOS SEROTIPOS Y PURIFICACION DE LOS POLISACARIDOS CAPSULARES POR COPRECIPITACION CON DETERGENTE, PRECIPITANCION EN ETANOL, EXTRACCION CON DISOLVENTES ORGANICOS Y ULTRACENTRIFUGACION; B) TRATAR LOS POLISACARIDOS CAPSULARES CON UN AGENTE DE DESACETILACION DURANTE 15 A 60 MINUTOS PARA DESTOXIFICARLOS; C) RECUPERAR LOS POLISACARIDOS; D) COMBINAR AL MENOS UNA PORCION DE POLISACARIDOS DE CADA UNO DE LOS SEROTIPOS PARA FORMAR UNA VACUNA INMUNOGENA NO PIROGENA.
ES553858A 1986-04-10 1986-04-10 Un metodo para preparar una vacuna polivalente de klebsiella inmunogenica Expired ES8708184A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES553858A ES8708184A1 (es) 1986-04-10 1986-04-10 Un metodo para preparar una vacuna polivalente de klebsiella inmunogenica

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES553858A ES8708184A1 (es) 1986-04-10 1986-04-10 Un metodo para preparar una vacuna polivalente de klebsiella inmunogenica

Publications (2)

Publication Number Publication Date
ES553858A0 ES553858A0 (es) 1987-10-01
ES8708184A1 true ES8708184A1 (es) 1987-10-01

Family

ID=8491115

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553858A Expired ES8708184A1 (es) 1986-04-10 1986-04-10 Un metodo para preparar una vacuna polivalente de klebsiella inmunogenica

Country Status (1)

Country Link
ES (1) ES8708184A1 (es)

Also Published As

Publication number Publication date
ES553858A0 (es) 1987-10-01

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