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Laboratorio Fides SA
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Laboratorio Fides SA
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Priority to ES557131ApriorityCriticalpatent/ES8707721A1/en
Publication of ES557131A0publicationCriticalpatent/ES557131A0/en
Publication of ES8707721A1publicationCriticalpatent/ES8707721A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
N2-Substd. benzimidazole N1-oxides of formula (I), in which R2 can be various radicals, for use as intermediates in synthesis of N,N'-di-substd. derivs. of 2-amino benzimidazole used as anti-histamine agents, are made by reaction of a N-substd. 2'-nitro formanilide of formula (II), with ammonium sulphide, in alcoholic solvent at ambient temp.