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Smith Kline and French Laboratories Ltd
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Smith Kline and French Laboratories Ltd
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Priority to ES550641ApriorityCriticalpatent/ES8703453A1/en
Publication of ES8703453A1publicationCriticalpatent/ES8703453A1/en
Publication of ES550641A0publicationCriticalpatent/ES550641A0/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Compounds of structure (I) <IMAGE> and pharmaceutically acceptable salts thereof, in which R5 and R6 are the same or different and are each hydrogen, C1-6 alkyl or C3-6 cycloalkyl or, together with the nitrogen atom to which they are bonded, form an azetidine, pyrrolidine, piperidine, piperazine, C1-4 N- alkylpiperazine or morpholine group, and one of R7 and R8 is halogen and the other is hydrogen, halogen or C1-6 alkyl; procedures for the preparation thereof, intermediate compounds useful in the preparation thereof, pharmaceutical compositions that contain them, and the use thereof as inhibitors of gastric acid secretion.
New amino-pyrimidine-carbanilides, processes for their preparation, medicaments containing these compounds and their use and also diamino-pyrimidinecarbanilides and processes for their preparation