ES8702901A1 - Un procedimiento de preparar una sal de 3-amino-5-(2-((2-guanidino-4-tiazolil)-metiltio)-etilamino)-4-metil-1,2,4,6-tiatriazino-1-1-dioxido. - Google Patents

Un procedimiento de preparar una sal de 3-amino-5-(2-((2-guanidino-4-tiazolil)-metiltio)-etilamino)-4-metil-1,2,4,6-tiatriazino-1-1-dioxido.

Info

Publication number
ES8702901A1
ES8702901A1 ES541539A ES541539A ES8702901A1 ES 8702901 A1 ES8702901 A1 ES 8702901A1 ES 541539 A ES541539 A ES 541539A ES 541539 A ES541539 A ES 541539A ES 8702901 A1 ES8702901 A1 ES 8702901A1
Authority
ES
Spain
Prior art keywords
thiatrizine
derivatives
salts
crystal
thiatriazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541539A
Other languages
English (en)
Other versions
ES541539A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis UK Holdings Ltd
Original Assignee
Hoechst UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848407896A external-priority patent/GB8407896D0/en
Priority claimed from GB848408011A external-priority patent/GB8408011D0/en
Application filed by Hoechst UK Ltd filed Critical Hoechst UK Ltd
Publication of ES541539A0 publication Critical patent/ES541539A0/es
Publication of ES8702901A1 publication Critical patent/ES8702901A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA SAL DE 3-AMINO-5-2-(2-GUANIDINO-4-TIAZOLIL)-METILTIO-ETILAMINO-4-METIL-1,2,4,6-TIATRIAZINO-1,1-DIOXIDO. CONSISTE EN HACER REACCIONAR 3-AMINO-5-2-(2GUANIDINO-4-TIAZOLIL)-METILTIO-ETILAMINO-4-METIL-1,2,4,6-TIATRIAZINO-1,1-DIOXIDO CON UN ACIDO TAL COMO ACIDO SULFURICO O ACIDO CLORHIDRICO, DONDE LA SAL TIENE UN ESPECTRO DE INFRARROJOS QUE MUESTRA LOS SIGUIENTES PICOS PRINCIPALES: NMAX 3450-2500 (MUY ANCHA), 3390, 3280, 3180, 3100, 3060, 1695, 1665, 1610, 1560, 1625, 1485, 1460, 1435, 1410, 1335, 2160, 1215, 1190, 1150, 1130, 1085, 1050, 980, 860, 720 Y 650 CMC1. TIENE UTILIDADES COMO POTENTE ANTAGONISTA H-2 DE HISTAMINA Y SE PUEDE UTILIZAR PARA TRATAR LOS ESTADOS QUE RESULTAN DE UNA ESTIMULACION POR HISTAMINA DE RECEPTORES H-2, BIEN A SOLAS O CONJUNTAMENTE CON ANTAGONISTAS H-1.
ES541539A 1984-03-27 1985-03-25 Un procedimiento de preparar una sal de 3-amino-5-(2-((2-guanidino-4-tiazolil)-metiltio)-etilamino)-4-metil-1,2,4,6-tiatriazino-1-1-dioxido. Expired ES8702901A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848407896A GB8407896D0 (en) 1984-03-27 1984-03-27 Thiatriazine derivatives
GB848408011A GB8408011D0 (en) 1984-03-28 1984-03-28 Thiatriazine derivatives

Publications (2)

Publication Number Publication Date
ES541539A0 ES541539A0 (es) 1987-01-16
ES8702901A1 true ES8702901A1 (es) 1987-01-16

Family

ID=26287519

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541539A Expired ES8702901A1 (es) 1984-03-27 1985-03-25 Un procedimiento de preparar una sal de 3-amino-5-(2-((2-guanidino-4-tiazolil)-metiltio)-etilamino)-4-metil-1,2,4,6-tiatriazino-1-1-dioxido.

Country Status (12)

Country Link
EP (1) EP0156286A3 (es)
AU (1) AU4045485A (es)
DK (1) DK136885A (es)
ES (1) ES8702901A1 (es)
FI (1) FI851179L (es)
GB (1) GB2158063A (es)
GR (1) GR850750B (es)
HU (1) HUT37789A (es)
IL (1) IL74705A0 (es)
MA (1) MA20389A1 (es)
NO (1) NO851220L (es)
PT (1) PT80162B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8419460D0 (en) * 1984-07-31 1984-09-05 Hoechst Uk Ltd 4-substituted-1 2 4 6-thiatriazine derivatives
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2001624B (en) * 1977-04-20 1982-03-03 Ici Ltd Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them
EP0104611A3 (en) * 1982-09-28 1985-06-12 Hoechst Uk Limited Thiatriazine derivatives

Also Published As

Publication number Publication date
GB8507663D0 (en) 1985-05-01
AU4045485A (en) 1985-10-03
EP0156286A3 (en) 1986-08-20
GB2158063A (en) 1985-11-06
GR850750B (es) 1985-07-22
FI851179L (fi) 1985-09-28
MA20389A1 (fr) 1985-10-01
DK136885D0 (da) 1985-03-26
FI851179A0 (fi) 1985-03-25
ES541539A0 (es) 1987-01-16
PT80162A (en) 1985-04-01
NO851220L (no) 1985-09-30
EP0156286A2 (en) 1985-10-02
DK136885A (da) 1985-09-28
PT80162B (en) 1987-01-16
HUT37789A (en) 1986-02-28
IL74705A0 (en) 1985-06-30

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