Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide CorpfiledCriticalWelfide Corp
Priority to ES553939ApriorityCriticalpatent/ES8702404A1/en
Publication of ES8702404A1publicationCriticalpatent/ES8702404A1/en
Publication of ES553939A0publicationCriticalpatent/ES553939A0/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
2-Amino-4-aminothienyl thiazole and derivs. of formula (I) and their acid-addn. salts are new. R=NH2, guanidino, mono- or di-alkylamino, alkenylamino, or PhNH or Ph2N (both opt. ring substd. by halogen, alkyl, CF3, alkoxy, NO2 or NH2) or acylamino; A=NH2, mono- or di-alkylamino, cyclic amino, alkanoylamino, NHCO(CH2)nNR1R2, NHCO(CH2)x(CHR4)y(CH2)zXR3 or NHCOR5; R1,R2= H or alkyl, or NR1R2=heterocyclic gp. n=0-3; R3=H, alkyl, akanoyl, mono- or di-alkylaminoalkyl or aryl, aralkyl or heteroaryl (all 3 opt. ring substd. by halogen, NH2, NO2, alkyl, alkoxy, mono- or di-alkylamino, mono- or dialkylaminoalkyl or cyclic aminoalkyl); X=O or S; R4=H or alkyl; x,y,z=0-3, provided that x+y+z=3 or less; R5=aryl, aralkyl or heteroaryl (all opt. ring substd. as defined above: Z=H or halogen, m=0-4.
Antibacterial benzoxazine and pyrido-oxazine derivatives, intermediates, pharmaceutical compositions containing these compounds, preparation and use thereof
Lactam derivatives, processes for the preparation thereof, pharmaceutical compositions comprising the same, and the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties
Substituted benzenesulphonylureas and thioureas, process for their preparation, their use as medicinal or diagnostic substances and medicinal products containing them
Trifluoromethylsulfonylphenyl or trifluoromethylsulfinylphenyl group containing 2-cyano-3-hydroxy-propenamide derivatives, process for their preparation, their use as medicaments and pharmaceutical compositions containing them
New indane derivatives, process for their preparation, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them