ES8702133A1 - Mejoras en la fabricacion de capsulas de medicamento - Google Patents

Mejoras en la fabricacion de capsulas de medicamento

Info

Publication number
ES8702133A1
ES8702133A1 ES502737A ES502737A ES8702133A1 ES 8702133 A1 ES8702133 A1 ES 8702133A1 ES 502737 A ES502737 A ES 502737A ES 502737 A ES502737 A ES 502737A ES 8702133 A1 ES8702133 A1 ES 8702133A1
Authority
ES
Spain
Prior art keywords
effective ingredient
capsule
rectum
medicament
osmotic pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502737A
Other languages
English (en)
Other versions
ES502737A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shin Etsu Chemical Co Ltd
Shionogi and Co Ltd
Original Assignee
Shin Etsu Chemical Co Ltd
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP7626480A external-priority patent/JPS572218A/ja
Priority claimed from JP56026624A external-priority patent/JPS57140710A/ja
Application filed by Shin Etsu Chemical Co Ltd, Shionogi and Co Ltd filed Critical Shin Etsu Chemical Co Ltd
Publication of ES502737A0 publication Critical patent/ES502737A0/es
Publication of ES8702133A1 publication Critical patent/ES8702133A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • A61K9/025Suppositories; Bougies; Bases therefor; Ovules characterised by shape or structure, e.g. hollow layered, coated
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00Preparation of cellulose ethers
    • C08B11/20Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B13/00Preparation of cellulose ether-esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

FABRICACION DE CAPSULAS DE MEDICAMENTO. COMPRENDE: A) MOLDEAR Y CONFORMAR UN CUERPO Y UN CAPUCHON DE CASCO DE CAPSULA DURA DE UN ESTER MIXTO; B) RELLENAR EL CUERPO DE CASCO DE CAPSULA DURA CON UNA MEDICINA LIQUIDA QUE TIENE UN INGREDIENTE ACTIVO CON UNA PRESION OSMOTICA MAS ALTA QUE LA PRESION OSMOTICA DEL FLUIDO RECTAL QUE ESTA COMPRENDIDO ENTRE 350 Y 2.000 M OSM/KG H2O; Y C) ENCAPUCHAR EL CUERPO DE CAPSULA DURA QUE LLEVA A LA MEDICINA LIQUIDA CON EL CAPUCHON DE CAPSULA DURA PARA FORMAR UNA CAPSULA DE MEDICAMENTO. LA CAPSULA DURA TIENE UN GROSOR DE PARED ENTRE 100 Y 150 MM. EL ESTER MIXTO ES UN ETER DE CELULOSA SELECCIONADO ENTRE ALQUILCELULOSA-, HIDROXIALQUILCELULOSA COMO (HIDROXIETIL, HIDROXIPROPILCELULOSA, HIDROCTIETIL, HIDROXIBUTILCELULOSA, HIDROXIPROPILETILCELULOSA Y OTROS), ESTERIFICADO POR GRUPOS ALIFATICOS DE MONOACILO (ACETILO, PROPILO Y PROPONILO) Y GRUPOS ACIDOS DE SUCCINILO. SE UTILIZA PARA FABRICAR SUPOSITORIOS.
ES502737A 1980-06-05 1981-06-03 Mejoras en la fabricacion de capsulas de medicamento Expired ES8702133A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7626480A JPS572218A (en) 1980-06-05 1980-06-05 Capsule agent for rectal administration
JP56026624A JPS57140710A (en) 1981-02-24 1981-02-24 Capsule agent for rectal administration

Publications (2)

Publication Number Publication Date
ES502737A0 ES502737A0 (es) 1987-01-01
ES8702133A1 true ES8702133A1 (es) 1987-01-01

Family

ID=26364434

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502737A Expired ES8702133A1 (es) 1980-06-05 1981-06-03 Mejoras en la fabricacion de capsulas de medicamento

Country Status (4)

Country Link
EP (1) EP0041665B1 (es)
DE (1) DE3171905D1 (es)
ES (1) ES8702133A1 (es)
GB (1) GB2077691B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH678697A5 (es) * 1989-04-03 1991-10-31 Warner Lambert Co
JPH0634807B2 (ja) * 1989-06-08 1994-05-11 信越化学工業株式会社 医薬用硬質カプセルの製造方法
FR2703908B1 (fr) * 1993-04-13 1995-06-02 Asta Medica Ag Forme pharmaceutique pour administration rectale de composés pharmacologiquement actifs.
DE19922537A1 (de) * 1999-05-10 2000-11-16 Roland Bodmeier Darreichungsform zur Applikation in Körperöffnungen
US20150203595A1 (en) * 2012-08-24 2015-07-23 Dow Global Technologies Llc Process for preparing an ester of a cellulose ether in the presence of an alkali metal carboxylate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR959520A (es) * 1947-01-11 1950-03-31
GB2006011B (en) * 1977-08-04 1982-04-21 Rhodes J Carminative preparations containing essential oila their active components
US4226981A (en) * 1977-09-28 1980-10-07 Shin-Etsu Chemical Co., Ltd. Ether-ester derivatives of cellulose and their applications
US4365060A (en) * 1979-04-28 1982-12-21 Shin-Etsu Chemical Co. Ltd. Enterosoluble capsules

Also Published As

Publication number Publication date
EP0041665A2 (en) 1981-12-16
EP0041665A3 (en) 1983-01-05
GB2077691B (en) 1983-11-02
GB2077691A (en) 1981-12-23
ES502737A0 (es) 1987-01-01
EP0041665B1 (en) 1985-08-21
DE3171905D1 (en) 1985-09-26

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