ES8701747A1 - "procedimiento para separar y obtener d-alfa-tocoferol" - Google Patents

"procedimiento para separar y obtener d-alfa-tocoferol"

Info

Publication number
ES8701747A1
ES8701747A1 ES542349A ES542349A ES8701747A1 ES 8701747 A1 ES8701747 A1 ES 8701747A1 ES 542349 A ES542349 A ES 542349A ES 542349 A ES542349 A ES 542349A ES 8701747 A1 ES8701747 A1 ES 8701747A1
Authority
ES
Spain
Prior art keywords
tocopherol
alpha
adducts
salts
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES542349A
Other languages
English (en)
Other versions
ES542349A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel Corp
Original Assignee
Henkel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Corp filed Critical Henkel Corp
Publication of ES542349A0 publication Critical patent/ES542349A0/es
Publication of ES8701747A1 publication Critical patent/ES8701747A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/723,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrane Compounds (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER ALFA-TOCOFEROL. SE AMINOALQUILA UN CONCENTRADO DE TOCOFEROLES, SE PONE EN CONTACTO ESTE PRODUCTO CON UN DISOLVENTE ORGANICO NO POLAR INMISCIBLE CON AGUA, PARA PROPORCIONAR DOS FASES, EN QUE DICHA FASE DE DISOLVENTE NO POLAR CONTIENE CUALQUIER ALFA-TOCOFEROL PRESENTE Y DICHA FASE DE DISOLVENTE POLAR CONTIENE DICHOS ADUCTOS DE AMINA Y COMPUESTOS NO-ALFA TOCOFEROLES; SE SEPARAN DICHAS FASES PARA PROPORCIONAR UNA FRACCION DE ALFA-TOCOFEROL NO POLAR Y UNA FRACCION DE ADUCTO DE AMINA Y COMPUESTOS NO ALFA-TOCOFEROLES, POLAR; SE REDUCE DICHO ADUCTO DE AMINA Y COMPUESTOS NO ALFA-TOCOFEROLES PARA FORMAR ALFA-TOCOFEROL; Y SE RECUPERA DICHO ALFA-TOCOFEROL. EL PROCEDIMIENTO ES APLICABLE PARA PRODUCIR D-ALFA-TOCOFEROL A PARTIR DE FUENTES VEGETALES NATURALES.
ES542349A 1984-04-17 1985-04-17 "procedimiento para separar y obtener d-alfa-tocoferol" Expired ES8701747A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60119484A 1984-04-17 1984-04-17

Publications (2)

Publication Number Publication Date
ES542349A0 ES542349A0 (es) 1986-12-16
ES8701747A1 true ES8701747A1 (es) 1986-12-16

Family

ID=24406573

Family Applications (1)

Application Number Title Priority Date Filing Date
ES542349A Expired ES8701747A1 (es) 1984-04-17 1985-04-17 "procedimiento para separar y obtener d-alfa-tocoferol"

Country Status (4)

Country Link
EP (1) EP0159018A3 (es)
JP (1) JPS60233068A (es)
AU (1) AU581216B2 (es)
ES (1) ES8701747A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4550183A (en) * 1984-08-02 1985-10-29 Henkel Corporation Purification of tocopherols
DE59605564D1 (de) * 1995-03-28 2000-08-17 Hoffmann La Roche Aminomethylierung von Tocopherolen
US5684132A (en) * 1995-12-04 1997-11-04 Basf Aktiengsellschaft Preparation of protected amines or alkylated amino acids
AUPR878201A0 (en) 2001-11-09 2001-12-06 Fujisawa Pharmaceutical Co., Ltd. New compounds
CA2741767C (en) * 2008-10-28 2017-09-12 Kieron E. Wesson Process for the production of alpha-tocotrienol and derivatives
EP3390377A1 (en) * 2015-12-16 2018-10-24 BioElectron Technology Corporation Improved methods for enriching alpha-tocotrienol from mixed tocol compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3819657A (en) * 1972-10-20 1974-06-25 Gen Mills Chem Inc Methylation of tocopherols
AU4567285A (en) * 1984-09-25 1986-04-10 Henkel Corporation Preparation of alpha-tocopherol from non alpha-tocopherols
AU4567385A (en) * 1984-11-19 1986-05-29 Henkel Corporation Preparation of alpha-tocopherol from non alpha-tocopherols
US4617406A (en) * 1985-02-11 1986-10-14 Henkel Corporation Purification of tocopherols

Also Published As

Publication number Publication date
AU4131785A (en) 1985-10-24
JPS60233068A (ja) 1985-11-19
AU581216B2 (en) 1989-02-16
ES542349A0 (es) 1986-12-16
EP0159018A2 (en) 1985-10-23
EP0159018A3 (en) 1986-10-01

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