ES8607930A1 - N-propyl pipecolic acid xylidide prepn. - Google Patents

N-propyl pipecolic acid xylidide prepn.

Info

Publication number
ES8607930A1
ES8607930A1 ES540231A ES540231A ES8607930A1 ES 8607930 A1 ES8607930 A1 ES 8607930A1 ES 540231 A ES540231 A ES 540231A ES 540231 A ES540231 A ES 540231A ES 8607930 A1 ES8607930 A1 ES 8607930A1
Authority
ES
Spain
Prior art keywords
propyl
xylidide
pipecolic acid
prepn
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES540231A
Other languages
Spanish (es)
Other versions
ES540231A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Priority to ES540231A priority Critical patent/ES8607930A1/en
Publication of ES540231A0 publication Critical patent/ES540231A0/en
Publication of ES8607930A1 publication Critical patent/ES8607930A1/en
Expired legal-status Critical Current

Links

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L-N-n-propyl pipecolic acid 2,6-xylidide for use as a local anaesthetic with low toxicity, is made by (a) resolving pipecolic acid to isolate the L-stereo-isomer; (b) chlorinating to obtain the acid chloride of formula (I); (c) reacting this with 2,6-xylidene to obtain the xylidide of formula (II); and (d) propylating with a propyl halide e.g. propyl bromide.
ES540231A 1985-01-28 1985-01-28 N-propyl pipecolic acid xylidide prepn. Expired ES8607930A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES540231A ES8607930A1 (en) 1985-01-28 1985-01-28 N-propyl pipecolic acid xylidide prepn.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES540231A ES8607930A1 (en) 1985-01-28 1985-01-28 N-propyl pipecolic acid xylidide prepn.

Publications (2)

Publication Number Publication Date
ES540231A0 ES540231A0 (en) 1986-06-01
ES8607930A1 true ES8607930A1 (en) 1986-06-01

Family

ID=8488676

Family Applications (1)

Application Number Title Priority Date Filing Date
ES540231A Expired ES8607930A1 (en) 1985-01-28 1985-01-28 N-propyl pipecolic acid xylidide prepn.

Country Status (1)

Country Link
ES (1) ES8607930A1 (en)

Also Published As

Publication number Publication date
ES540231A0 (en) 1986-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060311