ES8606309A1 - Procedimiento de obtencion de un derivado de la guanidina deintereses terapeutico - Google Patents

Procedimiento de obtencion de un derivado de la guanidina deintereses terapeutico

Info

Publication number
ES8606309A1
ES8606309A1 ES544816A ES544816A ES8606309A1 ES 8606309 A1 ES8606309 A1 ES 8606309A1 ES 544816 A ES544816 A ES 544816A ES 544816 A ES544816 A ES 544816A ES 8606309 A1 ES8606309 A1 ES 8606309A1
Authority
ES
Spain
Prior art keywords
prepn
guanidine
gastrointestinal infections
deriv
corresp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544816A
Other languages
English (en)
Other versions
ES544816A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lasa Laboratorios SA
Original Assignee
Lasa Laboratorios SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lasa Laboratorios SA filed Critical Lasa Laboratorios SA
Priority to ES544816A priority Critical patent/ES8606309A1/es
Publication of ES544816A0 publication Critical patent/ES544816A0/es
Publication of ES8606309A1 publication Critical patent/ES8606309A1/es
Expired legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE UN DERIVADO DE LA GUANIDINA, DE FORMULA (I). CONSISTE EN LA REACCION DE CICLACION DE LA 1-CLORO-2-HIDROXIPROPANONA CON DITIOCARBAMATO DE METILO; SEGUIDA DE LA OXIDACION DEL TIOTIAZOL FORMADO A LA CORRESPONDIENTE SULFONA, REACCION CON GUANIDINA Y CLORURO DE SULFONILO PARA FORMAR EL CORRESPONDIENTE SULFONATO; REACCION DE ESTE CON 3-MERCAPTOPROPIONITRILO, SEGUIDA DE METANOLISIS EN MEDIO ACIDO; Y, FINALMENTE TRATAMIENTO DEL PRODUCTO OBTENIDO CON SULFAMIDA EN PRESENCIA DE UNA AMINA TERCIARIA. ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LAS AFECCIONES GASTROINTESTINALES PRODUCIDAS POR HIPERSECRECION GASTRICA.
ES544816A 1985-07-02 1985-07-02 Procedimiento de obtencion de un derivado de la guanidina deintereses terapeutico Expired ES8606309A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES544816A ES8606309A1 (es) 1985-07-02 1985-07-02 Procedimiento de obtencion de un derivado de la guanidina deintereses terapeutico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES544816A ES8606309A1 (es) 1985-07-02 1985-07-02 Procedimiento de obtencion de un derivado de la guanidina deintereses terapeutico

Publications (2)

Publication Number Publication Date
ES544816A0 ES544816A0 (es) 1986-04-01
ES8606309A1 true ES8606309A1 (es) 1986-04-01

Family

ID=8489459

Family Applications (1)

Application Number Title Priority Date Filing Date
ES544816A Expired ES8606309A1 (es) 1985-07-02 1985-07-02 Procedimiento de obtencion de un derivado de la guanidina deintereses terapeutico

Country Status (1)

Country Link
ES (1) ES8606309A1 (es)

Also Published As

Publication number Publication date
ES544816A0 (es) 1986-04-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041016