ES8605254A1 - Procedimiento de obtencion de n-cinamilpiperazinas-n'-subs- tituidas - Google Patents

Procedimiento de obtencion de n-cinamilpiperazinas-n'-subs- tituidas

Info

Publication number
ES8605254A1
ES8605254A1 ES549465A ES549465A ES8605254A1 ES 8605254 A1 ES8605254 A1 ES 8605254A1 ES 549465 A ES549465 A ES 549465A ES 549465 A ES549465 A ES 549465A ES 8605254 A1 ES8605254 A1 ES 8605254A1
Authority
ES
Spain
Prior art keywords
substd
cinnamyl
phase
piperazine
cinnamyl piperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES549465A
Other languages
English (en)
Other versions
ES549465A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Servicios y Suministros Farmaceuticos SA
Original Assignee
Servicios y Suministros Farmaceuticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servicios y Suministros Farmaceuticos SA filed Critical Servicios y Suministros Farmaceuticos SA
Priority to ES549465A priority Critical patent/ES8605254A1/es
Publication of ES8605254A1 publication Critical patent/ES8605254A1/es
Publication of ES549465A0 publication Critical patent/ES549465A0/es
Expired legal-status Critical Current

Links

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE N-CINAMILPIPERAZINAS-N-SUSTITUIDAS, DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE LA N-CINAMIL-N,N-BIS(2-CLOROETIL)-AMINA CON UNA AMINA PRIMARIA DE FORMULA RNH2, EN LA QUE R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), EN CONDICIONES DE TRANSFERENCIA DE FASE, EN MEDIO BIFASICO AGUA-DISOLVENTE ORGANICO, SIENDO EL DISOLVENTE ORGANICO UNA MEZCLA DE CLOROFORMO Y ETANOL, EMPLEANDO COMO CATALIZADOR DE TRANSFERENCIA DE FASE UNA SAL DE AMONIO CUATERNARIO, EN PRESENCIA DE UNA BASE, A LA TEMPERATURA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES NEUROLEPTICOS Y REGULADORES DE LA ARRITMIA CARDIACA.
ES549465A 1985-11-30 1985-11-30 Procedimiento de obtencion de n-cinamilpiperazinas-n'-subs- tituidas Expired ES8605254A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES549465A ES8605254A1 (es) 1985-11-30 1985-11-30 Procedimiento de obtencion de n-cinamilpiperazinas-n'-subs- tituidas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES549465A ES8605254A1 (es) 1985-11-30 1985-11-30 Procedimiento de obtencion de n-cinamilpiperazinas-n'-subs- tituidas

Publications (2)

Publication Number Publication Date
ES8605254A1 true ES8605254A1 (es) 1986-03-16
ES549465A0 ES549465A0 (es) 1986-03-16

Family

ID=8490333

Family Applications (1)

Application Number Title Priority Date Filing Date
ES549465A Expired ES8605254A1 (es) 1985-11-30 1985-11-30 Procedimiento de obtencion de n-cinamilpiperazinas-n'-subs- tituidas

Country Status (1)

Country Link
ES (1) ES8605254A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241765B2 (en) 2001-05-22 2007-07-10 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
US7323478B2 (en) 2000-07-06 2008-01-29 Neurogen Corporation Melanin concentrating hormone receptor ligands

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7323478B2 (en) 2000-07-06 2008-01-29 Neurogen Corporation Melanin concentrating hormone receptor ligands
US7241765B2 (en) 2001-05-22 2007-07-10 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues

Also Published As

Publication number Publication date
ES549465A0 (es) 1986-03-16

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