ES8604917A3 - Prepn. of ranitidine for treatment of ulcers - by reacting 2-(((5-(di:methylamino)-methyl-2-furanyl) methyl) thio ethanamine with 1-nitro-3-methyl ketenimine - Google Patents
Prepn. of ranitidine for treatment of ulcers - by reacting 2-(((5-(di:methylamino)-methyl-2-furanyl) methyl) thio ethanamine with 1-nitro-3-methyl ketenimineInfo
- Publication number
- ES8604917A3 ES8604917A3 ES85543966A ES543966A ES8604917A3 ES 8604917 A3 ES8604917 A3 ES 8604917A3 ES 85543966 A ES85543966 A ES 85543966A ES 543966 A ES543966 A ES 543966A ES 8604917 A3 ES8604917 A3 ES 8604917A3
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- nitro
- thio
- ketenimine
- furanyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Furan Compounds (AREA)
Abstract
N-(2-(((5-dimethylamino methyl 2-furanyl) methyl) thio) ethyl) N'-methyl 2-nitro 1,1-ethene diamine of formula (I) is made by (a) treating a soln. of 1-methyl-thio- 1-methylamino 2-nitro ethene (IV) with a heavy metal salt selected from AgNO3, CoCl2, CoCl or HgCl, in organic solvent, e.g. methanol or acetonitrile, in presence of triethylamine and at ambient temp. to produce 1-nitro-3-methyl ketenimine CH3-N=C=CH-NO2 (III); and (b) reacting this with a cpd. of formula (II) at ambient temp. in presence of triethylamine and in methanol or acetonitrile to obtain (I) and its acceptable addn. salts.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES543966A ES543966A0 (en) | 1982-11-22 | 1985-06-07 | PROCEDURE FOR THE PREPARATION OF N- (2 - ((((5- (DIMETILA-MINO) -METIL-2-FURANIL) METHYL) THIO) ETIL) -N'-METHYL-2-NITRO-1,1- ETENDIAMINE |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU2608/82A YU42819B (en) | 1982-11-22 | 1982-11-22 | Process for preparing n-/2-///5-(dimethyl-amino)-methyl-2-furanyl/methyl/thio/ethyl-n'-methyl-2-nitro-1,1-ethene diamine |
ES543966A ES543966A0 (en) | 1982-11-22 | 1985-06-07 | PROCEDURE FOR THE PREPARATION OF N- (2 - ((((5- (DIMETILA-MINO) -METIL-2-FURANIL) METHYL) THIO) ETIL) -N'-METHYL-2-NITRO-1,1- ETENDIAMINE |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8604917A3 true ES8604917A3 (en) | 1986-03-01 |
ES543966A0 ES543966A0 (en) | 1986-03-01 |
Family
ID=26156106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543966A Granted ES543966A0 (en) | 1982-11-22 | 1985-06-07 | PROCEDURE FOR THE PREPARATION OF N- (2 - ((((5- (DIMETILA-MINO) -METIL-2-FURANIL) METHYL) THIO) ETIL) -N'-METHYL-2-NITRO-1,1- ETENDIAMINE |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES543966A0 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2036479A1 (en) * | 1990-11-09 | 1993-05-16 | Richter Gedeon Vegyeszet | Procedure for preparing 1 - (- 2 - ((5-dimethylamine-2-furyl) -metiltio) -amino-1-methylamino-2-nitroethylene. (Machine-translation by Google Translate, not legally binding) |
-
1985
- 1985-06-07 ES ES543966A patent/ES543966A0/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2036479A1 (en) * | 1990-11-09 | 1993-05-16 | Richter Gedeon Vegyeszet | Procedure for preparing 1 - (- 2 - ((5-dimethylamine-2-furyl) -metiltio) -amino-1-methylamino-2-nitroethylene. (Machine-translation by Google Translate, not legally binding) |
Also Published As
Publication number | Publication date |
---|---|
ES543966A0 (en) | 1986-03-01 |
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