Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation LtdfiledCriticalWellcome Foundation Ltd
Publication of ES8604263A1publicationCriticalpatent/ES8604263A1/es
Publication of ES545190A0publicationCriticalpatent/ES545190A0/es
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Abstract
METODO PARA PREPARAR PEPTIDOS FARMACEUTICAMENTE ACTIVOS. CONSISTE EN AMIDINAR A UN PEPTIDO EN EL QUE SU X2 ES UN RADICAL D DE FORMULA (II) CON 1-AMIDINO-3,5-DIMETILPIRAZOL O CON UN REACTIVO EQUIVALENTE, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES DE ACIDOS ORGANICOS E INORGANICOS. SIENDO: R1, H, ALQUILO DE 1 A 2 O UN GRUPO AMIDINO; R2 ALQUILO DE C 1 A 2; R3 H O CARBAMILO; R5 H; X2 UN RADICAL D DE FORMULA (III); Z Y Z2 IGUALES O DIFERENTES, H, HAL, NITRO O TRIFLUORMETILO; M, 2, 3 O 4 Y N 0, 1 O 2. SE UTILIZAN EN MEDICINA Y VETERINARIA PARA EL TRATAMIENTO DE LA DIARREA, DISENTERIA, LA SUPRESION DE LA TOS Y PARA LA PREVENCION Y ALIVIO DEL DOLOR.
ES545190A1985-06-101985-07-15Un metodo para preparar peptidos farmaceuticamente activos
ExpiredES8604263A1
(es)
Peptidi comprendenti la sequenza diaamminoacidi del peptide derivante dal gene della calcitonina,loro sali e complessi farmaceuticamente accettabili e composizioni farmaceutiche che li contengono