Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Antibioticos SA
Original Assignee
Antibioticos SA
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Filing date
Publication date
Application filed by Antibioticos SAfiledCriticalAntibioticos SA
Priority to ES543854ApriorityCriticalpatent/ES8603954A1/en
Publication of ES543854A0publicationCriticalpatent/ES543854A0/en
Publication of ES8603954A1publicationCriticalpatent/ES8603954A1/en
The process consists of (a) prodn. of protoplasts of the bacteria S.jumonjinensis ATCC 29864 (b) conversion with a plasmid vector with one or more genetic markers (c) selection of the cells which have formed protoplasts and introduced the vector, in accordance with the genetic marker (d) cultivation of these cells under aerobic conditions in a culture medium contg. carbon and nitrogen sources and mineral salts at 25-37 deg.C and (e) recovery of clavulanic acid from the culture medium.
ES543854A1985-06-031985-06-03Clavulanic acid prodn. by genetic engineering
ExpiredES8603954A1
(en)