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Apotecnia S A
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Apotecnia S A
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Application filed by Apotecnia S AfiledCriticalApotecnia S A
Priority to ES545359ApriorityCriticalpatent/ES8603833A1/en
Publication of ES545359A0publicationCriticalpatent/ES545359A0/en
Publication of ES8603833A1publicationCriticalpatent/ES8603833A1/en
The cpds. of formula (I) in which R1 is phenyl, R2 and R3 are lower alkyl or alkoxy-alkyl, R4 and R5 are H or lower alkyl and R6 is H or lower alkyl, are made by treating an ester of formula (II) with a cpd. of formula (III) in presence of an alcoholic or aq. ammonia soln. or a primary aliphatic amine R6-NH2. Reaction is in an inert solvent, e.g. methanol, ethanol or other, at 20-90 deg.C for 2-48 h..