ES8602714A1 - 2-Guanidino-4-amidino:alkyl thiazole(s) prepn. - Google Patents
2-Guanidino-4-amidino:alkyl thiazole(s) prepn.Info
- Publication number
- ES8602714A1 ES8602714A1 ES544882A ES544882A ES8602714A1 ES 8602714 A1 ES8602714 A1 ES 8602714A1 ES 544882 A ES544882 A ES 544882A ES 544882 A ES544882 A ES 544882A ES 8602714 A1 ES8602714 A1 ES 8602714A1
- Authority
- ES
- Spain
- Prior art keywords
- prepn
- guanidino
- amidino
- formula
- hrs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
Thiazole derivs. of formula (I), in which R1 is H, lower alkyl, aralkyl or other, X is O, S or CH2, and n is a whole number e.g. 1 or 2, are made by (a) treating a nitrile of formula (II) with a thiol or thiophenol in presence of a catalyst, e.g. HCl at 0-25 deg.C for 5 hrs. to 10 days to obtain thio-imidates of formula (III) and (b) treating (III) with a nitrogenated cpd. e.g. NH4Cl, gaseous ammonia, methylamine or other, in a solvent, e.g. methanol, at 20-70 deg.C for 2-72 hrs. to give (I).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES544882A ES8602714A1 (en) | 1985-07-05 | 1985-07-05 | 2-Guanidino-4-amidino:alkyl thiazole(s) prepn. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES544882A ES8602714A1 (en) | 1985-07-05 | 1985-07-05 | 2-Guanidino-4-amidino:alkyl thiazole(s) prepn. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES544882A0 ES544882A0 (en) | 1985-12-01 |
| ES8602714A1 true ES8602714A1 (en) | 1985-12-01 |
Family
ID=8489470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES544882A Expired ES8602714A1 (en) | 1985-07-05 | 1985-07-05 | 2-Guanidino-4-amidino:alkyl thiazole(s) prepn. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8602714A1 (en) |
-
1985
- 1985-07-05 ES ES544882A patent/ES8602714A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES544882A0 (en) | 1985-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19961226 |