ES8601979A1 - N-Substd. 3-amino thieno (3,4-d) iso:thiazole-1,1-di:oxide derivs. - Google Patents

N-Substd. 3-amino thieno (3,4-d) iso:thiazole-1,1-di:oxide derivs.

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Publication number
ES8601979A1
ES8601979A1 ES529904A ES529904A ES8601979A1 ES 8601979 A1 ES8601979 A1 ES 8601979A1 ES 529904 A ES529904 A ES 529904A ES 529904 A ES529904 A ES 529904A ES 8601979 A1 ES8601979 A1 ES 8601979A1
Authority
ES
Spain
Prior art keywords
amino
lower alkyl
substd
mono
thiazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529904A
Other languages
Spanish (es)
Other versions
ES529904A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/468,221 external-priority patent/US4490527A/en
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of ES529904A0 publication Critical patent/ES529904A0/en
Publication of ES8601979A1 publication Critical patent/ES8601979A1/en
Expired legal-status Critical Current

Links

Abstract

Heterocyclic cpds. of formula (I) and their salts (where B=a gp. (Id), (Ie) or (If), the dotted line being a bond when B=Id or If and absent when B+Ie R=H, mono- or di-halo, amino, nitro, cyano, hydroxy, trifluoromethyl, mercapto, lower alkyl, lower alkoxy, alkanoyl, lower cycloalkyl, carboxy, akoxycarbonyl, mono- or di-(lower alkyl)amino, alkanoylamino, lower alkylthio, lower alkylsulphonyl, sulphamoyl (opt. lower alkyl substd.) or phenyl (opt. substd. by halo, lower alkyl, lower alkoxy, trifluoromethyl, hydroxy, amino, cyano or nitro) X=S, SO, SO2 or C=O A=(Ia), (Ib) or (Ic) n=1-4, R1=H or R2CH2-, R2= mono- or di-(lower alkyl)amino, mono- or di-(lower alkyl)amino-lower alkyl, 2-furyl-methylamino, benzylamino, 5-7C cycloalkylamino, 1-pyrrolidinyl, 1-piperidinyl, 1-hexahydro-azepinyl, 1-octahydro-azocinyl, 3-thiazolidinyl, 4-morpholinyl or 4-thiomerpholinyl and R3=H or 1-piperidinyl-methyl, with the condition that when R3=1-piperdinylmethyl, then R1=H). A=(Ia), (Ib) or (Ic) X=SO2 B=(Ie) and when A=(Ic) then n=3 and one of R1 and R3=1-piperidinylmethyl and the other=H.
ES529904A 1983-02-22 1984-02-21 N-Substd. 3-amino thieno (3,4-d) iso:thiazole-1,1-di:oxide derivs. Expired ES8601979A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/468,221 US4490527A (en) 1982-09-30 1983-02-22 Benzo-fused heterocyclic anti-ulcer agents
US8311653 1983-04-28

Publications (2)

Publication Number Publication Date
ES529904A0 ES529904A0 (en) 1985-11-16
ES8601979A1 true ES8601979A1 (en) 1985-11-16

Family

ID=26768955

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529904A Expired ES8601979A1 (en) 1983-02-22 1984-02-21 N-Substd. 3-amino thieno (3,4-d) iso:thiazole-1,1-di:oxide derivs.

Country Status (1)

Country Link
ES (1) ES8601979A1 (en)

Also Published As

Publication number Publication date
ES529904A0 (en) 1985-11-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001