ES8504197A1 - (1,2,4)triazolo(4,3-a)quinoxalin-4-amine derivative and composition - Google Patents

(1,2,4)triazolo(4,3-a)quinoxalin-4-amine derivative and composition

Info

Publication number
ES8504197A1
ES8504197A1 ES526533A ES526533A ES8504197A1 ES 8504197 A1 ES8504197 A1 ES 8504197A1 ES 526533 A ES526533 A ES 526533A ES 526533 A ES526533 A ES 526533A ES 8504197 A1 ES8504197 A1 ES 8504197A1
Authority
ES
Spain
Prior art keywords
formula
amine
amine derivative
quinoxalin
triazolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526533A
Other languages
Spanish (es)
Other versions
ES526533A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES526533A0 publication Critical patent/ES526533A0/en
Publication of ES8504197A1 publication Critical patent/ES8504197A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDURE FOR THE PREPARATION OF A 1,2,4-TRIAZOLO4,3-AQUINOXALIN-4-AMINE DERIVATIVE. IT CONSISTS IN REACTIONING 4-CHLORINE COMPOUND OF FORMULA (II) WITH A FORMULA AMINE HNR2R3 TO OBTAIN 4-AMINO COMPOUND, CUAL IT IS REACTED WITH AN ALCANOIC ANHYDRIDE TO OBTAIN A 1,2,4-TRIAZOLO4,3-AQUINOXALIN-4-AMINE OF FORMULA (I), WHERE X AND X ARE H, FLUORINE, CHLORINE, BROMINE AND METOXY; R1 IS H, LOWER ALKYL, LOWER PERFLUOROALKYL AND PHENYL; AND R2 AND R3 ARE H, LOWER RENT, PHENYLALKYL FROM C 1 TO 3 AND OTHERS. THE REACTION IS CARRIED OUT AT A TEMPERATURE BETWEEN 0ºC AND 60ºC FOR 2 TO 24 HOURS. THEY ARE USEFUL FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH DEPRESSION, SUCH AS ANTIDEPRESSANTS AND DEFATIGANTS. (Machine-translation by Google Translate, not legally binding)
ES526533A 1982-10-18 1983-10-17 (1,2,4)triazolo(4,3-a)quinoxalin-4-amine derivative and composition Expired ES8504197A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43477182A 1982-10-18 1982-10-18

Publications (2)

Publication Number Publication Date
ES526533A0 ES526533A0 (en) 1985-04-01
ES8504197A1 true ES8504197A1 (en) 1985-04-01

Family

ID=23725622

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526533A Expired ES8504197A1 (en) 1982-10-18 1983-10-17 (1,2,4)triazolo(4,3-a)quinoxalin-4-amine derivative and composition

Country Status (17)

Country Link
JP (1) JPS5989684A (en)
KR (1) KR860001493B1 (en)
CA (1) CA1207772A (en)
CS (1) CS248711B2 (en)
DD (1) DD215545A5 (en)
ES (1) ES8504197A1 (en)
FI (1) FI74011C (en)
GR (1) GR78952B (en)
IN (1) IN160956B (en)
NO (1) NO160142C (en)
NZ (1) NZ205986A (en)
PH (1) PH19080A (en)
PL (1) PL141382B1 (en)
PT (1) PT77507B (en)
SU (1) SU1246895A3 (en)
YU (1) YU43331B (en)
ZA (1) ZA837691B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4707261B2 (en) * 2001-05-15 2011-06-22 日本エンバイロケミカルズ株式会社 Quinoxaline compound and industrial bactericidal composition
JP4529535B2 (en) * 2004-04-30 2010-08-25 住友化学株式会社 Bactericidal use of 4-amino [1,2,4] triazolo [4,3-a] quinoxaline compounds
ES2599054T3 (en) * 2006-12-13 2017-01-31 Aska Pharmaceutical Co., Ltd. Quinoxaline derivatives
UY32111A (en) * 2008-09-10 2010-04-30 Alcon Res Ltd HETEROCICLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF A DISEASE
AU2011301518B2 (en) * 2010-09-16 2014-07-03 Hutchison Medipharma Limited Fused heteroaryls and their uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008322A (en) * 1975-06-10 1977-02-15 Eli Lilly And Company Triazolo(4,3-a)quinoxalines for control of rice

Also Published As

Publication number Publication date
YU207483A (en) 1986-02-28
NO160142B (en) 1988-12-05
NO833770L (en) 1984-04-24
PL244194A1 (en) 1985-03-26
FI74011B (en) 1987-08-31
ES526533A0 (en) 1985-04-01
KR860001493B1 (en) 1986-09-27
GR78952B (en) 1984-10-02
FI74011C (en) 1987-12-10
PH19080A (en) 1985-12-19
NZ205986A (en) 1986-06-11
CS248711B2 (en) 1987-02-12
SU1246895A3 (en) 1986-07-23
NO160142C (en) 1989-03-15
FI833781A0 (en) 1983-10-17
DD215545A5 (en) 1984-11-14
JPH039915B2 (en) 1991-02-12
JPS5989684A (en) 1984-05-23
KR840006485A (en) 1984-11-30
PL141382B1 (en) 1987-07-31
CA1207772A (en) 1986-07-15
YU43331B (en) 1989-06-30
PT77507B (en) 1986-05-28
PT77507A (en) 1983-11-01
IN160956B (en) 1987-08-22
FI833781A (en) 1984-04-19
ZA837691B (en) 1985-05-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203