ES8501391A1 - Prepn. of ethyl:fluoro di:hydro piperazinyl oxo-quinoline carboxylic a - Google Patents

Prepn. of ethyl:fluoro di:hydro piperazinyl oxo-quinoline carboxylic a

Info

Publication number
ES8501391A1
ES8501391A1 ES524358A ES524358A ES8501391A1 ES 8501391 A1 ES8501391 A1 ES 8501391A1 ES 524358 A ES524358 A ES 524358A ES 524358 A ES524358 A ES 524358A ES 8501391 A1 ES8501391 A1 ES 8501391A1
Authority
ES
Spain
Prior art keywords
piperazinyl
fluoro
ethyl
oxo
prepn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524358A
Other languages
Spanish (es)
Other versions
ES524358A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ABC IST BIOLOG CHEM SpA
Original Assignee
ABC IST BIOLOG CHEM SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ABC IST BIOLOG CHEM SpA filed Critical ABC IST BIOLOG CHEM SpA
Priority to ES524358A priority Critical patent/ES524358A0/en
Priority to KR1019830005273A priority patent/KR850001190A/en
Priority to FI842687A priority patent/FI842687A/en
Priority to IT21854/84A priority patent/IT1178493B/en
Priority to GR75320A priority patent/GR79960B/el
Priority to PT78926A priority patent/PT78926B/en
Priority to NO842941A priority patent/NO842941L/en
Priority to DK355884A priority patent/DK355884A/en
Publication of ES8501391A1 publication Critical patent/ES8501391A1/en
Publication of ES524358A0 publication Critical patent/ES524358A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PT--78926 A 1-Ethyl 6-fluoro 1,4-dihydro 7-(1-piperazinyl) 4-oxo quinoline 3-carboxylic acid, of formula (I) is made by a process comprising two phases of reaction with the piperazine and a final phase in presence of an alkali metal hydroxide. The process requires lower quantities of piperazine and gives a pure product in increased yield compared with conventional processes.
ES524358A 1983-07-22 1983-07-22 PROCEDURE TO PREPARE ACID 1-ETIL-6-FLUO-1,4-DIHIDRO-7- (1-PIPERACINIL) -4-OXOQUINOLIN-3-CARBOXILICO. Granted ES524358A0 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES524358A ES524358A0 (en) 1983-07-22 1983-07-22 PROCEDURE TO PREPARE ACID 1-ETIL-6-FLUO-1,4-DIHIDRO-7- (1-PIPERACINIL) -4-OXOQUINOLIN-3-CARBOXILICO.
KR1019830005273A KR850001190A (en) 1983-07-22 1983-11-07 Method for preparing 1-ethyl-6-fluoro-1,4-dihydro-7- (1-piperazinyl) -4-oxoquinoline-3-carboxylic acid
FI842687A FI842687A (en) 1983-07-22 1984-07-04 FOR EXAMINATION OF FRAMSTAELLNING AV 1-ETHYL-6-FLUORO-1,4-DIHYDRO-7- (1-PIPERAZINYL) -4-OXO-QUINOLINE-3-CARBOXYL SYRA.
IT21854/84A IT1178493B (en) 1983-07-22 1984-07-12 PROCEDURE FOR THE PREPARATION OF 1-ETHYL-6-FLUORO-1,4-DIHYDRO-7- (1-PIPERAZIL) -4-OXOCHINOLIN-3-CARBOXYLIC ACID
GR75320A GR79960B (en) 1983-07-22 1984-07-16
PT78926A PT78926B (en) 1983-07-22 1984-07-17 A process for the preparation of 1-ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxoquinoline-3-carboxylic acid
NO842941A NO842941L (en) 1983-07-22 1984-07-18 PROCEDURE FOR PREPARING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-7- (1-PIPERAZINYL) -4-OXOCOQINOLIN-3-CARBOXYLIC ACID
DK355884A DK355884A (en) 1983-07-22 1984-07-20 METHOD FOR PREPARING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-7- (1-PIPERAZINYL) -4-OXOQUINOLIN-3-CARBOXYLIC ACID

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES524358A ES524358A0 (en) 1983-07-22 1983-07-22 PROCEDURE TO PREPARE ACID 1-ETIL-6-FLUO-1,4-DIHIDRO-7- (1-PIPERACINIL) -4-OXOQUINOLIN-3-CARBOXILICO.

Publications (2)

Publication Number Publication Date
ES8501391A1 true ES8501391A1 (en) 1984-12-16
ES524358A0 ES524358A0 (en) 1984-12-16

Family

ID=8486067

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524358A Granted ES524358A0 (en) 1983-07-22 1983-07-22 PROCEDURE TO PREPARE ACID 1-ETIL-6-FLUO-1,4-DIHIDRO-7- (1-PIPERACINIL) -4-OXOQUINOLIN-3-CARBOXILICO.

Country Status (8)

Country Link
KR (1) KR850001190A (en)
DK (1) DK355884A (en)
ES (1) ES524358A0 (en)
FI (1) FI842687A (en)
GR (1) GR79960B (en)
IT (1) IT1178493B (en)
NO (1) NO842941L (en)
PT (1) PT78926B (en)

Also Published As

Publication number Publication date
FI842687A (en) 1985-01-23
PT78926A (en) 1984-08-01
IT8421854A0 (en) 1984-07-12
DK355884A (en) 1985-01-23
ES524358A0 (en) 1984-12-16
DK355884D0 (en) 1984-07-20
PT78926B (en) 1986-06-02
FI842687A0 (en) 1984-07-04
IT1178493B (en) 1987-09-09
KR850001190A (en) 1985-03-16
IT8421854A1 (en) 1986-01-12
GR79960B (en) 1984-10-31
NO842941L (en) 1985-01-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601