ES8406420A1 - Therapeutically useful alkylbenzylidene derivatives - Google Patents

Therapeutically useful alkylbenzylidene derivatives

Info

Publication number
ES8406420A1
ES8406420A1 ES527584A ES527584A ES8406420A1 ES 8406420 A1 ES8406420 A1 ES 8406420A1 ES 527584 A ES527584 A ES 527584A ES 527584 A ES527584 A ES 527584A ES 8406420 A1 ES8406420 A1 ES 8406420A1
Authority
ES
Spain
Prior art keywords
radical
derivatives
alkylbenzylidene
therapeutically useful
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES527584A
Other languages
Spanish (es)
Other versions
ES527584A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES8406420A1 publication Critical patent/ES8406420A1/en
Publication of ES527584A0 publication Critical patent/ES527584A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic

Abstract

Novel benzylidene derivatives of the general formula: < IMAGE > wherein n represents an integer from 1 to 12, R1 is alkyl or alkenyl radical having 2 to 6 carbon atoms, R2 represents an amino radical, a hydroxy radical, or a group -OM in which M represents an alkali metal or alkaline earth metal, and X1, X2 and X3 each represent, independently of one another, a hydrogen atom, the methoxy radical or alkyl radical having 1 to 4 carbon atoms, are useful as antidepressants, anticonvulsants, ulcer inhibitors and gastric secretion inhibitors and also as anxiolytic, analgesic and anti-inflammatory agents.
ES527584A 1982-11-29 1983-11-28 A PROCEDURE FOR THE PREPARATION OF BENCILIDENIC DERIVATIVES Granted ES527584A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8219981A FR2536746A1 (en) 1982-11-29 1982-11-29 ALKYL BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
ES8406420A1 true ES8406420A1 (en) 1984-08-01
ES527584A0 ES527584A0 (en) 1984-08-01

Family

ID=9279618

Family Applications (1)

Application Number Title Priority Date Filing Date
ES527584A Granted ES527584A0 (en) 1982-11-29 1983-11-28 A PROCEDURE FOR THE PREPARATION OF BENCILIDENIC DERIVATIVES

Country Status (22)

Country Link
JP (1) JPS59116253A (en)
AU (1) AU2174583A (en)
BE (1) BE898323A (en)
CA (1) CA1204774A (en)
CH (1) CH656876A5 (en)
DE (1) DE3343000A1 (en)
DK (1) DK544283D0 (en)
ES (1) ES527584A0 (en)
FI (1) FI834339A (en)
FR (1) FR2536746A1 (en)
GB (1) GB2131024B (en)
GR (1) GR81258B (en)
HU (1) HU190636B (en)
IL (1) IL70334A0 (en)
IT (1) IT1167029B (en)
LU (1) LU85106A1 (en)
NL (1) NL8304070A (en)
NO (1) NO834361L (en)
NZ (1) NZ206409A (en)
PT (1) PT77752B (en)
SE (1) SE8305306L (en)
ZA (1) ZA838862B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2577923B1 (en) * 1985-02-26 1988-09-09 Synthelabo CARBOXYLATED DIPHENYLAZOMETHINES, THEIR PREPARATION AND THEIR APPLICATION

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319338A1 (en) * 1975-08-01 1977-02-25 Synthelabo NEW A-PHENYL BENZYLIDENIC DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
FR2516509B1 (en) * 1981-11-18 1985-07-26 Synthelabo BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
NO790646L (en) * 1978-02-27 1979-08-28 Synthelabo PROCEDURE FOR THE PREPARATION OF BENZYLIDE DERIVATIVES
FR2422628A1 (en) * 1978-04-14 1979-11-09 Synthelabo BENZYLIDENIC ESTERS AND THEIR APPLICATION IN THERAPEUTICS

Also Published As

Publication number Publication date
LU85106A1 (en) 1985-07-17
JPS59116253A (en) 1984-07-05
DK544283D0 (en) 1983-11-28
PT77752B (en) 1986-06-02
GB2131024B (en) 1986-02-19
FI834339A (en) 1984-05-30
NL8304070A (en) 1984-06-18
NZ206409A (en) 1986-07-11
CH656876A5 (en) 1986-07-31
SE8305306D0 (en) 1983-09-29
IL70334A0 (en) 1984-02-29
BE898323A (en) 1984-05-28
IT1167029B (en) 1987-05-06
DE3343000A1 (en) 1984-05-30
ZA838862B (en) 1984-07-25
ES527584A0 (en) 1984-08-01
SE8305306L (en) 1984-05-30
GB8331714D0 (en) 1984-01-04
HU190636B (en) 1986-09-29
IT8323927A0 (en) 1983-11-28
GB2131024A (en) 1984-06-13
FI834339A0 (en) 1983-11-28
GR81258B (en) 1984-12-11
PT77752A (en) 1983-12-01
NO834361L (en) 1984-05-30
CA1204774A (en) 1986-05-20
FR2536746B1 (en) 1985-03-08
AU2174583A (en) 1984-06-07
FR2536746A1 (en) 1984-06-01

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