ES8401441A1 - Procedimiento de obtencion de un derivado del acido valerianico. - Google Patents

Procedimiento de obtencion de un derivado del acido valerianico.

Info

Publication number
ES8401441A1
ES8401441A1 ES517665A ES517665A ES8401441A1 ES 8401441 A1 ES8401441 A1 ES 8401441A1 ES 517665 A ES517665 A ES 517665A ES 517665 A ES517665 A ES 517665A ES 8401441 A1 ES8401441 A1 ES 8401441A1
Authority
ES
Spain
Prior art keywords
hypolipaemic
prepn
valeric acid
formula
cpd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES517665A
Other languages
English (en)
Other versions
ES517665A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES517665A priority Critical patent/ES517665A0/es
Publication of ES8401441A1 publication Critical patent/ES8401441A1/es
Publication of ES517665A0 publication Critical patent/ES517665A0/es
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DEL ACIDO VALERIANICO, DE FORMULA ESTRUCTURAL (I).COMPRENDE LAS SIGUIENTES FASES: PRIMERA, SE HACE REACCIONAR LA ISOBUTIROFENONA CON SODAMIDA Y DESPUES CON 1,3-DIBROMO-PROPANO, EN UN HIDROCARBURO AROMATICO ELEGIDO ENTRE BENCENO, TOLUENO O XILENOS, SEGUIDO DE ADICION DE AGUA, OBTENIENDOSE UN COMPUESTO INTERMEDIARIO DE FORMULA (II); SEGUNDA, DICHO COMPUESTO INTERMEDIO SE HACE REACCIONAR, UNA VEZ PURIFICADO POR DESTILACION, CON 2,5-DIMETIL-FENOL EN UNA DISOLUCION ACUOSA DE UN HIDROXIDO ALCALINO O ALCALINOTERREO, PARA OBTENERUN COMPUESTO INTERMEDIO DE FORMULA (III); Y POR ULTIMO, DICHO COMPUESTO INTERMEDIO DE FORMULA (III), UNA VEZ PURIFICADO POR DESTILACION, SE HACE REACCIONAR CON UN EXCESO DE TERT-BUTOXIDO POTASICO EN ANISOL A UNA TEMPERATURA DE 150 GRADOS.DE APLICACION EN CLINICA COMO HIPOLIPEMIANTE.
ES517665A 1982-11-17 1982-11-17 Procedimiento de obtencion de un derivado del acido valerianico. Granted ES517665A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES517665A ES517665A0 (es) 1982-11-17 1982-11-17 Procedimiento de obtencion de un derivado del acido valerianico.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES517665A ES517665A0 (es) 1982-11-17 1982-11-17 Procedimiento de obtencion de un derivado del acido valerianico.

Publications (2)

Publication Number Publication Date
ES8401441A1 true ES8401441A1 (es) 1983-12-16
ES517665A0 ES517665A0 (es) 1983-12-16

Family

ID=8484978

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517665A Granted ES517665A0 (es) 1982-11-17 1982-11-17 Procedimiento de obtencion de un derivado del acido valerianico.

Country Status (1)

Country Link
ES (1) ES517665A0 (es)

Also Published As

Publication number Publication date
ES517665A0 (es) 1983-12-16

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