ES8401071A1 - Un procedimiento para la preparacion de un compuesto pentaciclico anti-depresivo. - Google Patents
Un procedimiento para la preparacion de un compuesto pentaciclico anti-depresivo.Info
- Publication number
- ES8401071A1 ES8401071A1 ES508465A ES508465A ES8401071A1 ES 8401071 A1 ES8401071 A1 ES 8401071A1 ES 508465 A ES508465 A ES 508465A ES 508465 A ES508465 A ES 508465A ES 8401071 A1 ES8401071 A1 ES 8401071A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- hydrogen
- alkoxy
- phenyl
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 9
- 239000001257 hydrogen Substances 0.000 abstract 9
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- -1 polymethylene Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/20—[b, f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8041558 | 1980-12-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES508465A0 ES508465A0 (es) | 1983-11-16 |
| ES8401071A1 true ES8401071A1 (es) | 1983-11-16 |
Family
ID=10518265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES508465A Expired ES8401071A1 (es) | 1980-12-31 | 1981-12-30 | Un procedimiento para la preparacion de un compuesto pentaciclico anti-depresivo. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4442098A (https=) |
| EP (1) | EP0055546B1 (https=) |
| JP (1) | JPS57134483A (https=) |
| AU (1) | AU551160B2 (https=) |
| CA (1) | CA1167439A (https=) |
| DE (1) | DE3165289D1 (https=) |
| ES (1) | ES8401071A1 (https=) |
| GB (1) | GB2091247B (https=) |
| GR (1) | GR76380B (https=) |
| IE (1) | IE52235B1 (https=) |
| NZ (1) | NZ199291A (https=) |
| PT (1) | PT74210B (https=) |
| ZA (1) | ZA818804B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0088575B1 (en) * | 1982-03-05 | 1986-12-30 | Beecham Group Plc | Pentacyclic compounds |
| EP0090552A3 (en) * | 1982-03-27 | 1984-04-25 | Beecham Group Plc | Pentacyclic compounds |
| JP2008509925A (ja) * | 2004-08-13 | 2008-04-03 | オメロス コーポレイション | 新規のセロトニンレセプターリガンドおよびそれらの使用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL129434C (https=) * | 1966-03-12 | |||
| NL154511B (nl) * | 1967-07-07 | 1977-09-15 | Organon Nv | Werkwijze ter bereiding van piperazinederivaten, werkwijze ter bereiding van een farmaceutisch preparaat, dat een dergelijke verbinding bevat en vormstukken bereid volgens deze werkwijze. |
-
1981
- 1981-12-14 EP EP81305861A patent/EP0055546B1/en not_active Expired
- 1981-12-14 GB GB8137604A patent/GB2091247B/en not_active Expired
- 1981-12-14 DE DE8181305861T patent/DE3165289D1/de not_active Expired
- 1981-12-16 NZ NZ199291A patent/NZ199291A/en unknown
- 1981-12-18 US US06/332,347 patent/US4442098A/en not_active Expired - Fee Related
- 1981-12-21 ZA ZA818804A patent/ZA818804B/xx unknown
- 1981-12-28 PT PT74210A patent/PT74210B/pt unknown
- 1981-12-29 GR GR66927A patent/GR76380B/el unknown
- 1981-12-30 IE IE3084/81A patent/IE52235B1/en unknown
- 1981-12-30 ES ES508465A patent/ES8401071A1/es not_active Expired
- 1981-12-30 JP JP56215973A patent/JPS57134483A/ja active Pending
- 1981-12-30 CA CA000393370A patent/CA1167439A/en not_active Expired
- 1981-12-31 AU AU79131/81A patent/AU551160B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US4442098A (en) | 1984-04-10 |
| AU7913181A (en) | 1982-07-08 |
| EP0055546B1 (en) | 1984-08-01 |
| DE3165289D1 (en) | 1984-09-06 |
| ZA818804B (en) | 1982-11-24 |
| IE813084L (en) | 1982-06-30 |
| IE52235B1 (en) | 1987-08-19 |
| PT74210A (en) | 1982-01-01 |
| ES508465A0 (es) | 1983-11-16 |
| GB2091247B (en) | 1984-07-18 |
| NZ199291A (en) | 1986-01-24 |
| EP0055546A1 (en) | 1982-07-07 |
| JPS57134483A (en) | 1982-08-19 |
| PT74210B (en) | 1983-05-30 |
| GB2091247A (en) | 1982-07-28 |
| CA1167439A (en) | 1984-05-15 |
| GR76380B (https=) | 1984-08-06 |
| AU551160B2 (en) | 1986-04-17 |
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