ES8307830A1 - "un procedimiento para la preparacion de sales de fosfomicina". - Google Patents

"un procedimiento para la preparacion de sales de fosfomicina".

Info

Publication number
ES8307830A1
ES8307830A1 ES511527A ES511527A ES8307830A1 ES 8307830 A1 ES8307830 A1 ES 8307830A1 ES 511527 A ES511527 A ES 511527A ES 511527 A ES511527 A ES 511527A ES 8307830 A1 ES8307830 A1 ES 8307830A1
Authority
ES
Spain
Prior art keywords
phosphomycin
prepn
salts
reaction
r3so3h
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511527A
Other languages
English (en)
Other versions
ES511527A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia Antibioticos Farma SA
Original Assignee
Pharmacia Antibioticos Farma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Antibioticos Farma SA filed Critical Pharmacia Antibioticos Farma SA
Priority to ES511527A priority Critical patent/ES511527A0/es
Publication of ES8307830A1 publication Critical patent/ES8307830A1/es
Publication of ES511527A0 publication Critical patent/ES511527A0/es
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE SALES DE FOSFOMICINA. SE HACE REACCIONAR LA SAL MONO(+)-ALFA-FENETILAMONIO)-(-)CIS-1,2-EPOXIPROPIL)-FOSFONATO MONOHIDRATADA CON UN COMPUESTO BASICO ORGANICO (II), EN MEDIO ALCOHOLICO, A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 65 C DURANTE UN TIEMPO DE 3 HORAS EN PRESENCIA DE UN ACIDO SULFONICO R<3-SO<3H, EN QUE R<3 ES UN GRUPO ALQUILO, ARILO O ARALQUILO. SE OBTIENE EL COMPUESTO (I) EN QUE UNO DE LOS R Y R>2 ES UN PROTON (H+) Y EL OTRO REPRESENTA EL CATION TRIS(HIDROXIMETIL)- -AMONIO-METANO O BIEN AMBOS REPRESENTAN DICHO CATION.
ES511527A 1982-04-20 1982-04-20 "un procedimiento para la preparacion de sales de fosfomicina". Granted ES511527A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES511527A ES511527A0 (es) 1982-04-20 1982-04-20 "un procedimiento para la preparacion de sales de fosfomicina".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES511527A ES511527A0 (es) 1982-04-20 1982-04-20 "un procedimiento para la preparacion de sales de fosfomicina".

Publications (2)

Publication Number Publication Date
ES8307830A1 true ES8307830A1 (es) 1983-07-01
ES511527A0 ES511527A0 (es) 1983-07-01

Family

ID=8484020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511527A Granted ES511527A0 (es) 1982-04-20 1982-04-20 "un procedimiento para la preparacion de sales de fosfomicina".

Country Status (1)

Country Link
ES (1) ES511527A0 (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2239536A1 (es) * 2004-03-05 2005-09-16 Labiana Development, S.L. Procedimiento de obtencion de la sal de metiloxiranilfosfonato de trometamina con una relacion molar de 1:1.
EP1762573A1 (en) 2005-09-08 2007-03-14 Interquim, S.A. De C.V. A process for the preparation of fosfomycin salts
CN104086592A (zh) * 2014-07-22 2014-10-08 桂林华信制药有限公司 一种磷霉素氨丁三醇的制备方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2239536A1 (es) * 2004-03-05 2005-09-16 Labiana Development, S.L. Procedimiento de obtencion de la sal de metiloxiranilfosfonato de trometamina con una relacion molar de 1:1.
EP1762573A1 (en) 2005-09-08 2007-03-14 Interquim, S.A. De C.V. A process for the preparation of fosfomycin salts
CN104086592A (zh) * 2014-07-22 2014-10-08 桂林华信制药有限公司 一种磷霉素氨丁三醇的制备方法

Also Published As

Publication number Publication date
ES511527A0 (es) 1983-07-01

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Legal Events

Date Code Title Description
PC1A Transfer granted
PC1A Transfer granted
RD1A Patent seized

Effective date: 20010926

FD2A Announcement of lapse in spain

Effective date: 20151230