ES8307830A1 - "un procedimiento para la preparacion de sales de fosfomicina". - Google Patents
"un procedimiento para la preparacion de sales de fosfomicina".Info
- Publication number
- ES8307830A1 ES8307830A1 ES511527A ES511527A ES8307830A1 ES 8307830 A1 ES8307830 A1 ES 8307830A1 ES 511527 A ES511527 A ES 511527A ES 511527 A ES511527 A ES 511527A ES 8307830 A1 ES8307830 A1 ES 8307830A1
- Authority
- ES
- Spain
- Prior art keywords
- phosphomycin
- prepn
- salts
- reaction
- r3so3h
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PREPARACION DE SALES DE FOSFOMICINA. SE HACE REACCIONAR LA SAL MONO(+)-ALFA-FENETILAMONIO)-(-)CIS-1,2-EPOXIPROPIL)-FOSFONATO MONOHIDRATADA CON UN COMPUESTO BASICO ORGANICO (II), EN MEDIO ALCOHOLICO, A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 65 C DURANTE UN TIEMPO DE 3 HORAS EN PRESENCIA DE UN ACIDO SULFONICO R<3-SO<3H, EN QUE R<3 ES UN GRUPO ALQUILO, ARILO O ARALQUILO. SE OBTIENE EL COMPUESTO (I) EN QUE UNO DE LOS R Y R>2 ES UN PROTON (H+) Y EL OTRO REPRESENTA EL CATION TRIS(HIDROXIMETIL)- -AMONIO-METANO O BIEN AMBOS REPRESENTAN DICHO CATION.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES511527A ES511527A0 (es) | 1982-04-20 | 1982-04-20 | "un procedimiento para la preparacion de sales de fosfomicina". |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES511527A ES511527A0 (es) | 1982-04-20 | 1982-04-20 | "un procedimiento para la preparacion de sales de fosfomicina". |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8307830A1 true ES8307830A1 (es) | 1983-07-01 |
ES511527A0 ES511527A0 (es) | 1983-07-01 |
Family
ID=8484020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES511527A Granted ES511527A0 (es) | 1982-04-20 | 1982-04-20 | "un procedimiento para la preparacion de sales de fosfomicina". |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES511527A0 (es) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2239536A1 (es) * | 2004-03-05 | 2005-09-16 | Labiana Development, S.L. | Procedimiento de obtencion de la sal de metiloxiranilfosfonato de trometamina con una relacion molar de 1:1. |
EP1762573A1 (en) | 2005-09-08 | 2007-03-14 | Interquim, S.A. De C.V. | A process for the preparation of fosfomycin salts |
CN104086592A (zh) * | 2014-07-22 | 2014-10-08 | 桂林华信制药有限公司 | 一种磷霉素氨丁三醇的制备方法 |
-
1982
- 1982-04-20 ES ES511527A patent/ES511527A0/es active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2239536A1 (es) * | 2004-03-05 | 2005-09-16 | Labiana Development, S.L. | Procedimiento de obtencion de la sal de metiloxiranilfosfonato de trometamina con una relacion molar de 1:1. |
EP1762573A1 (en) | 2005-09-08 | 2007-03-14 | Interquim, S.A. De C.V. | A process for the preparation of fosfomycin salts |
CN104086592A (zh) * | 2014-07-22 | 2014-10-08 | 桂林华信制药有限公司 | 一种磷霉素氨丁三醇的制备方法 |
Also Published As
Publication number | Publication date |
---|---|
ES511527A0 (es) | 1983-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted | ||
PC1A | Transfer granted | ||
RD1A | Patent seized |
Effective date: 20010926 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20151230 |