ES8307101A1 - "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza". - Google Patents
"procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza".Info
- Publication number
- ES8307101A1 ES8307101A1 ES511716A ES511716A ES8307101A1 ES 8307101 A1 ES8307101 A1 ES 8307101A1 ES 511716 A ES511716 A ES 511716A ES 511716 A ES511716 A ES 511716A ES 8307101 A1 ES8307101 A1 ES 8307101A1
- Authority
- ES
- Spain
- Prior art keywords
- prepn
- high purity
- peg
- factor viii
- factor concentrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER UN PREPARADO CONCENTRADO DE FACTOR ANTIHEMOFILICO DE ALTA PUREZA, EXENTO PRACTICAMENTE DE FIBRINOGENO. SE BASA EN LA PURIFICACION DE CRIOPRECIPITADO EN FRIO, EXTRACCION DEL FACTOR VIII EN TAMPON TRIS/CLH, DESACTIVACION DEL COMPLEJO PROTROMBINICO CON HEPARINA, PRECIPITACION SELECTIVA DEL FIBRINOGENO CON PEG Y POSTERIOR PURIFICACION DEL FACTOR VIII CON PEG, ELIMINACION DE LA HEPARINA Y PEG RESIDUAL SIN PERDIDA DE FACTOR VIII. EL CRIOPRECIPITADO SE OBTIENE SIN ETANOL FRIO, DEJANDO QUE LA FRACCION CRIOPRECIPITABLE LO HAGA POR SI MISMA Y EN TIEMPO RELATIVAMENTE CORTO, NO SUPERIOR A LAS DOS HORAS Y A UNA TEMPERATURA ENTRE 0 C Y 2 C
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES511716A ES8307101A1 (es) | 1982-04-26 | 1982-04-26 | "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza". |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES511716A ES8307101A1 (es) | 1982-04-26 | 1982-04-26 | "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza". |
Publications (2)
Publication Number | Publication Date |
---|---|
ES511716A0 ES511716A0 (es) | 1983-07-01 |
ES8307101A1 true ES8307101A1 (es) | 1983-07-01 |
Family
ID=8484060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES511716A Expired ES8307101A1 (es) | 1982-04-26 | 1982-04-26 | "procedimiento para la obtencion de un preparado concentrado de factor antihemofilico de alta pureza". |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8307101A1 (es) |
-
1982
- 1982-04-26 ES ES511716A patent/ES8307101A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES511716A0 (es) | 1983-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970612 |