ES8304997A1 - Cephalosporin derivatives - Google Patents

Cephalosporin derivatives

Info

Publication number
ES8304997A1
ES8304997A1 ES514106A ES514106A ES8304997A1 ES 8304997 A1 ES8304997 A1 ES 8304997A1 ES 514106 A ES514106 A ES 514106A ES 514106 A ES514106 A ES 514106A ES 8304997 A1 ES8304997 A1 ES 8304997A1
Authority
ES
Spain
Prior art keywords
cephalosporin derivatives
derivatives
hydrazonocephem
ylthio
acetyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514106A
Other languages
Spanish (es)
Other versions
ES514106A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CRAFT SUD
Original Assignee
CRAFT SUD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CRAFT SUD filed Critical CRAFT SUD
Publication of ES514106A0 publication Critical patent/ES514106A0/en
Publication of ES8304997A1 publication Critical patent/ES8304997A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel hydrazonocephem derivatives of the general formula:- < IMAGE > wherein R is an acetyloxy or 1-methyl- 1H-tetrazol-5-ylthio radical and the pharmaceutically-acceptable, non- toxic salts thereof, in the sin and/or anti configuration, have antibacterial activity and can be incorporated into pharmaceutical compositions.
ES514106A 1981-07-21 1982-07-19 Cephalosporin derivatives Expired ES8304997A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8123033A IT1211080B (en) 1981-07-21 1981-07-21 BIOLOGICALLY ACTIVE HYDRAZONOCEFEM.

Publications (2)

Publication Number Publication Date
ES514106A0 ES514106A0 (en) 1983-04-01
ES8304997A1 true ES8304997A1 (en) 1983-04-01

Family

ID=11203099

Family Applications (1)

Application Number Title Priority Date Filing Date
ES514106A Expired ES8304997A1 (en) 1981-07-21 1982-07-19 Cephalosporin derivatives

Country Status (7)

Country Link
JP (1) JPS5824589A (en)
DE (1) DE3227284A1 (en)
ES (1) ES8304997A1 (en)
FR (1) FR2510117B1 (en)
GB (1) GB2102423B (en)
IT (1) IT1211080B (en)
PT (1) PT75281A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT381944B (en) * 1984-04-10 1986-12-10 Biochemie Gmbh METHOD FOR PRODUCING CEPHALOSPORINANTIBIOTICS
PL1965798T3 (en) 2005-12-07 2012-02-29 Basilea Pharmaceutica Ag Useful monobactam antibiotics
EP2105435A4 (en) * 2007-01-10 2011-06-15 Mitsubishi Tanabe Pharma Corp Hydrazone derivative
CN112010821A (en) * 2020-09-29 2020-12-01 山东金城医药化工有限公司 Recovery method of ethyl aminothiazoly loximate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1208015A (en) * 1967-03-23 1970-10-07 Glaxo Lab Ltd Cephalosporins
GB1208014A (en) * 1967-03-23 1970-10-07 Glaxo Lab Ltd Cephalosporins
DK400074A (en) 1973-10-01 1975-06-09 Ciba Geigy Ag
IT1081809B (en) * 1977-06-07 1985-05-21 Isf Spa HYDRAZE CEPHALOSPORINE
DE2818263A1 (en) * 1978-04-26 1979-11-08 Bayer Ag BETA LACTAMANTIBIOTICS

Also Published As

Publication number Publication date
IT1211080B (en) 1989-09-29
JPS5824589A (en) 1983-02-14
FR2510117B1 (en) 1985-07-05
IT8123033A0 (en) 1981-07-21
GB2102423B (en) 1985-08-14
ES514106A0 (en) 1983-04-01
GB2102423A (en) 1983-02-02
FR2510117A1 (en) 1983-01-28
DE3227284A1 (en) 1983-02-24
PT75281A (en) 1982-08-01

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