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Laboratorios Frumtost Prem SA
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Laboratorios Frumtost Prem SA
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Publication date
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Priority to ES514549ApriorityCriticalpatent/ES8304968A1/es
Publication of ES514549A0publicationCriticalpatent/ES514549A0/es
Publication of ES8304968A1publicationCriticalpatent/ES8304968A1/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DEL DERIVADO PIPERAZINICO DE ACCION ANOREXIGENA 6-CLORO-2-(1-PIPERAZINIL)PIRAZINA DE FORMULA (I). SE HACE REACCIONAR UN ESTER HALOFOSFORICO DE FORMULA (II) EN DONDE X ES UN ATOMO DE BROMO O DE CLORO Y R Y R SON GRUPOS ALCOHILO O ARILO CON PIPERAZINA EN LA PROPORCION MOLAR DE 1:2 PARA DAR DIALCOXIFOSFORILPIPERAZINAS DE FORMULA GENERAL (III). SE HACEN REACCIONAR LAS FOSFORILPIPERAZINAS CON 2,6-DICLOROPIRAZINA PARA DAR LOS DERIVADOS DE FORMULA GENERAL (IV). POR ULTIMO SE REALIZA LA HIDROLISIS ACIDA DE ESTOS ULTIMOS DERIVADOS.
ES514549A1982-07-301982-07-30"procedimiento para la obtencion de un derivado piperazinico de accion anorexigena".
ExpiredES8304968A1
(es)
Complejos aminoacido-metalicos utiles como estabilizadores para los polimeros de haluro vinilicos y composiciones estabilizadoras y estabilizadas que los contienen