Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Laboratorios Frumtost Prem SA
Original Assignee
Laboratorios Frumtost Prem SA
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Filing date
Publication date
Application filed by Laboratorios Frumtost Prem SAfiledCriticalLaboratorios Frumtost Prem SA
Priority to ES513135ApriorityCriticalpatent/ES8304573A1/es
Publication of ES513135A0publicationCriticalpatent/ES513135A0/es
Publication of ES8304573A1publicationCriticalpatent/ES8304573A1/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO PURINICO, LA 2-AMINO-6-HIDROXI-9-(2-HIDROXI-ETOXIMETIL)PURINA, QUE TIENE APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIVIRICA. CONSISTE EN LA REACCION DE LA GUANINA CON UN AGENTE DE SILILACION TAL COMO EL HEXAMETILDISILAZANO; SEGUIDA DE LA REACCION DEL DERIVADO TRIS-TRIMETILSILILADO DE LA GUANINA CON YODOMETIL-(TRIMETILSILIL)OXI ETIL ETER, EN BENCENO O TOLUENO, EN PRESENCIA DE TIRETILAMINA, A UNA TEMPERATURA ENTRE 80 C Y 110 C; Y TRATAMIENTO HIDROLITICO DEL PRODUCTO OBTENIDO CON ALCOHOLES ALIFATICOS INFERIORES CONTENIENDO 5-10% DE AGUA.
ES513135A1982-06-151982-06-15"procedimiento para la obtencion de un derivado purinico de accion antivirica".
ExpiredES8304573A1
(es)