ES8304144A1 - 4-hetero ring-substituted-2,6-di-tert-butyl-phenol derivative - Google Patents
4-hetero ring-substituted-2,6-di-tert-butyl-phenol derivativeInfo
- Publication number
- ES8304144A1 ES8304144A1 ES509781A ES509781A ES8304144A1 ES 8304144 A1 ES8304144 A1 ES 8304144A1 ES 509781 A ES509781 A ES 509781A ES 509781 A ES509781 A ES 509781A ES 8304144 A1 ES8304144 A1 ES 8304144A1
- Authority
- ES
- Spain
- Prior art keywords
- agent
- butyl
- substituted
- hetero ring
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
NEW MATERIAL:The 4-hetero ring-substituted-2,6-di-t-butyl-phenol derivative of formulaI(one of R1-R4 is group of formula II, and the other three are H, halogen, substituted or unsubstituted lower alkyl, etc. n is 0-2 dotted line represents a double bond or a single bond) or its salt. EXAMPLE:6-(3,5-Di-t-butyl-4-hydroxyphenyl)-2,3-dihydroimidazo[2,1-b]th iazole. USE:Antiphlogistic agent, antipyretic and analgesic agent, antiarthritic agent, antirheumatic agent, and immunoregulating agent. PROCESS:A compound of formulaIwherein n=0 can be prepared by reacting the 2-amino-thiazole derivative or 2-aminothiazoline derivative of formula III with the haloacetyl dervative of formula IV. The product can be converted to the monoxide compound (n=1) and the dioxide compound (n=2) ty treating with an oxidizing agent (e.g. H2O2).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56023515A JPS57150692A (en) | 1981-02-19 | 1981-02-19 | 4-hetero ring-substituted-2,6-di-tert-butyl-phenol derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8304144A1 true ES8304144A1 (en) | 1983-02-16 |
| ES509781A0 ES509781A0 (en) | 1983-02-16 |
Family
ID=12112578
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509780A Expired ES8302722A1 (en) | 1981-02-19 | 1982-02-19 | 4-hetero ring-substituted-2,6-di-tert-butyl-phenol derivative |
| ES509781A Granted ES509781A0 (en) | 1981-02-19 | 1982-02-19 | A PRODUCTION METHOD OF A SUBSTITUTED 3,5-DI-T-BUTIL-4-HI-DROXIFENIL-HETEROCICLICO COMPOUND. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509780A Expired ES8302722A1 (en) | 1981-02-19 | 1982-02-19 | 4-hetero ring-substituted-2,6-di-tert-butyl-phenol derivative |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS57150692A (en) |
| CA (2) | CA1181074A (en) |
| ES (2) | ES8302722A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868183A (en) * | 1986-07-21 | 1989-09-19 | Otsuka Pharmaceutical Factory, Inc. | N-pyrazinyl substituted P-aminophenols |
-
1981
- 1981-02-19 JP JP56023515A patent/JPS57150692A/en active Granted
-
1982
- 1982-02-17 CA CA000396500A patent/CA1181074A/en not_active Expired
- 1982-02-17 CA CA000396501A patent/CA1181751A/en not_active Expired
- 1982-02-19 ES ES509780A patent/ES8302722A1/en not_active Expired
- 1982-02-19 ES ES509781A patent/ES509781A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CA1181751A (en) | 1985-01-29 |
| JPH0139434B2 (en) | 1989-08-21 |
| ES509780A0 (en) | 1983-01-16 |
| CA1181074A (en) | 1985-01-15 |
| JPS57150692A (en) | 1982-09-17 |
| ES509781A0 (en) | 1983-02-16 |
| ES8302722A1 (en) | 1983-01-16 |
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