ES8304121A1 - Procedimiento para la obtencion del diclohidrato de 8,9-dimetil-4(3-(4-metilpiperazin-1-il)propionamido)-1,2,3,4,4a,9b-hexahidrodibenzofuran-3-ona. - Google Patents

Procedimiento para la obtencion del diclohidrato de 8,9-dimetil-4(3-(4-metilpiperazin-1-il)propionamido)-1,2,3,4,4a,9b-hexahidrodibenzofuran-3-ona.

Info

Publication number
ES8304121A1
ES8304121A1 ES511297A ES511297A ES8304121A1 ES 8304121 A1 ES8304121 A1 ES 8304121A1 ES 511297 A ES511297 A ES 511297A ES 511297 A ES511297 A ES 511297A ES 8304121 A1 ES8304121 A1 ES 8304121A1
Authority
ES
Spain
Prior art keywords
ona
dimethyl
hexahidrodibenzofuran
methylpiperazin
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511297A
Other languages
English (en)
Other versions
ES511297A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to ES511297A priority Critical patent/ES511297A0/es
Publication of ES8304121A1 publication Critical patent/ES8304121A1/es
Publication of ES511297A0 publication Critical patent/ES511297A0/es
Granted legal-status Critical Current

Links

Landscapes

  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

_(PROCEDIMIENTO PARA LA OBTENCION DEL DICLORHIDRATO DE 8,9B-DIMETIL-4 3-(4-METILPIPERAZIN-1-IL)PROPIONAMIDO -1,2,3,4,4A, 9B,-HEXAHIDRODIBENZOFURAN-3-ONA . CONSISTE EN HACER REACCIONAR LA 4-(3-CLORO-PROPIONAMIDO)-8,9B-DIMETIL-1,2,3,4,4A,9BHEXAHIDRODIBENZOFURAN-3-ONA, EN CONDICIONES ADECUADAS DE N-ALQUILACION CON N-METILPIPERAZINA. EL PRODUCTO RESULTANTE, SE PURIFICA POR METODOS CONVENCIONALES. LA REACCION PUEDE EFECTUARSE EN UN DISOLVENTE AROMATICO COMO BENCENO-TOLUENO, O UNA MEZCLA DE ESTOS Y CLOROFORMO; ADEMAS TIENE LUGAR EN PRESENCIA DE UNA BASE CAPAZ DE NEUTRALIZAR EL ACIDO CLORHIDRICO QUE SE DESPRENDE; LAS BASES EMPLEADAS SON NA CO , K CO Y OTRAS. LA TEMPERATURA OSCILA ENTRE LA DE REFLUJO DEL DISOLVENTE Y 35 C, SIENDO PREFERIBLE DE 50 A 60 C. AGENTE ANTITUSIVO.
ES511297A 1982-04-08 1982-04-08 Procedimiento para la obtencion del diclohidrato de 8,9-dimetil-4(3-(4-metilpiperazin-1-il)propionamido)-1,2,3,4,4a,9b-hexahidrodibenzofuran-3-ona. Granted ES511297A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES511297A ES511297A0 (es) 1982-04-08 1982-04-08 Procedimiento para la obtencion del diclohidrato de 8,9-dimetil-4(3-(4-metilpiperazin-1-il)propionamido)-1,2,3,4,4a,9b-hexahidrodibenzofuran-3-ona.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES511297A ES511297A0 (es) 1982-04-08 1982-04-08 Procedimiento para la obtencion del diclohidrato de 8,9-dimetil-4(3-(4-metilpiperazin-1-il)propionamido)-1,2,3,4,4a,9b-hexahidrodibenzofuran-3-ona.

Publications (2)

Publication Number Publication Date
ES8304121A1 true ES8304121A1 (es) 1983-02-16
ES511297A0 ES511297A0 (es) 1983-02-16

Family

ID=8483981

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511297A Granted ES511297A0 (es) 1982-04-08 1982-04-08 Procedimiento para la obtencion del diclohidrato de 8,9-dimetil-4(3-(4-metilpiperazin-1-il)propionamido)-1,2,3,4,4a,9b-hexahidrodibenzofuran-3-ona.

Country Status (1)

Country Link
ES (1) ES511297A0 (es)

Also Published As

Publication number Publication date
ES511297A0 (es) 1983-02-16

Similar Documents

Publication Publication Date Title
BG34336A3 (en) Method for obtaining derivates of phtalazine-4-yl-acetic acid
ES8706715A1 (es) Un procedimiento para preparar un derivado de uridina.
ES8304121A1 (es) Procedimiento para la obtencion del diclohidrato de 8,9-dimetil-4(3-(4-metilpiperazin-1-il)propionamido)-1,2,3,4,4a,9b-hexahidrodibenzofuran-3-ona.
GR61241B (en) 2,6-dimethyl-3-methoxycarbonyl-4-(2-nitrophenyl)-1,4-dihydropyridin-5-isobutylester of carbonic acid preparation process thereof and use thereof as coronartherapeutical
JPS51141894A (en) Process for preparing guanine.
JPS5254084A (en) Manufacture of 2-gamma-glutamylamino-4-hexynic acid and/or 2-gamma-glutamylamino- 3-hydroxy-4-hexynic acid
JPS51146481A (en) Process for preparing arabinofuranosylcytosine derivatives
BG34451A3 (en) Method for obtaining substituted 4h-5-triazolo/3,4c/thieno /2,3e/ 1,4-diazepines
JPS51138698A (en) Process preparing 2-cycloalkylthioadenine s
JPS51138642A (en) Process for preparing guanidinobenzoic acid derivatives
JPS5223086A (en) Novel method of preparing 2,3- dioxopiperazine
ES8207172A1 (es) Procedimiento de obtencion de nuevos benzofuranildioxolanos con actividad farmacologica.
JPS51146479A (en) Process for preparing new morpholinone derivatives
JPS5246064A (en) Process for preparation of novel tetrahydrofuran derivatives
ATE1315T1 (de) 3-azabicyclo(3.1.0)hexan-derivate und verfahren zu ihrer herstellung.
JPS5236635A (en) Process for preparation of 4-(3'- dimethylaminopropoxy)-meta- phenylen ediamine
JPS5278888A (en) Synthesis of novel quinazoline derivatives
JPS5239672A (en) Process for preparing indole-2-allyl-3- thioeter compounds
ES8505937A1 (es) Un metodo para la preparacion de una 2-metil-4-hidroxi-2h-1, 2-benzotiacin-1, 1-dioxido-3-(n-2-piridil)-carboxamida
JPS5259142A (en) Process for preparation of stilbene derivatives
JPS5257155A (en) Process for preparing cyclic compounds
JPS525734A (en) Process for preparation of 5**aminoo3**5* dideoxyribostamycin
JPS51118768A (en) Method for preparing 4-amino-2-pyridone derivatives
JPS5231067A (en) Synthesis of 2-(2-formyl-1-pyrrolyl)- benzophenone derivatives
JPS51136643A (en) Process for preparation of aromatic ester derivatives