ES8303351A1 - Novel 2-amino-benzoic acid derivative, manufacture and pharmaceutical composition - Google Patents

Novel 2-amino-benzoic acid derivative, manufacture and pharmaceutical composition

Info

Publication number
ES8303351A1
ES8303351A1 ES512605A ES512605A ES8303351A1 ES 8303351 A1 ES8303351 A1 ES 8303351A1 ES 512605 A ES512605 A ES 512605A ES 512605 A ES512605 A ES 512605A ES 8303351 A1 ES8303351 A1 ES 8303351A1
Authority
ES
Spain
Prior art keywords
amino
novel
manufacture
pharmaceutical composition
benzoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512605A
Other languages
Spanish (es)
Other versions
ES512605A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES512605A priority Critical patent/ES512605A0/en
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Publication of ES8303351A1 publication Critical patent/ES8303351A1/en
Publication of ES512605A0 publication Critical patent/ES512605A0/en
Priority to PH28864A priority patent/PH24088A/en
Priority to ZA833206A priority patent/ZA833206B/en
Priority to CA000427487A priority patent/CA1193598A/en
Priority to DE8383104501T priority patent/DE3380989D1/en
Priority to JP58078414A priority patent/JPS5931762A/en
Priority to EP83104501A priority patent/EP0094065B1/en
Priority to PH32097A priority patent/PH21204A/en
Priority to US07/059,911 priority patent/US4767767A/en
Granted legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for obtaining derivatives of 2-aminobenzoic acid. A general formula (II) intermediate is reactioned with the x-r compound "in which x is oh or a halogen like chlorine or bromine. The reaction has place in an aromatic solvent such as tolueno a reflux, in the presence of sodium hydride or rhodium as catalysts, then evaports the solvent to vacuum, diluing the residue in a chlorine solvent; filter and wash the organic extract with water and an aqueous dissolution of a mineral base to then purify the compound obtained (I) by chromatography in column or crystallization. (Machine-translation by Google Translate, not legally binding)
ES512605A 1982-05-06 1982-05-06 "PROCEDURE FOR OBTAINING NEW DERIVATIVES OF 2-AMINOBENZOIC ACID". Granted ES512605A0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ES512605A ES512605A0 (en) 1982-05-06 1982-05-06 "PROCEDURE FOR OBTAINING NEW DERIVATIVES OF 2-AMINOBENZOIC ACID".
PH28864A PH24088A (en) 1982-05-06 1983-05-05 New 2-amino-benzoic acid derivatives and process for their preparation
ZA833206A ZA833206B (en) 1982-05-06 1983-05-05 2-amino-benzoic acid derivatives and processes for their production
CA000427487A CA1193598A (en) 1982-05-06 1983-05-05 2-amino-benzoic acid derivatives and processes for their production
EP83104501A EP0094065B1 (en) 1982-05-06 1983-05-06 2-aminobenzoic acid derivatives, a process for their preparation and pharmaceutical compositions
DE8383104501T DE3380989D1 (en) 1982-05-06 1983-05-06 2-AMINOBENZOAIC DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS.
JP58078414A JPS5931762A (en) 1982-05-06 1983-05-06 Novel 2-amino-benzoic acid derivative, manufacture and pharmaceutical composition
PH32097A PH21204A (en) 1982-05-06 1985-04-03 Process for the preparation of new 2-amino-benzoic acid derivatives
US07/059,911 US4767767A (en) 1982-05-06 1987-07-17 2-pyrrolidinylethyl-2-(7-trifluoromethyl-4-quinolyl-aminobenzoate having analgesic, antipyretic and anti-inflammatory activities

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES512605A ES512605A0 (en) 1982-05-06 1982-05-06 "PROCEDURE FOR OBTAINING NEW DERIVATIVES OF 2-AMINOBENZOIC ACID".

Publications (2)

Publication Number Publication Date
ES8303351A1 true ES8303351A1 (en) 1983-02-16
ES512605A0 ES512605A0 (en) 1983-02-16

Family

ID=8484207

Family Applications (1)

Application Number Title Priority Date Filing Date
ES512605A Granted ES512605A0 (en) 1982-05-06 1982-05-06 "PROCEDURE FOR OBTAINING NEW DERIVATIVES OF 2-AMINOBENZOIC ACID".

Country Status (4)

Country Link
JP (1) JPS5931762A (en)
ES (1) ES512605A0 (en)
PH (2) PH24088A (en)
ZA (1) ZA833206B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2233059B1 (en) * 1973-06-13 1976-09-03 Roussel Uclaf

Also Published As

Publication number Publication date
PH24088A (en) 1990-03-05
ES512605A0 (en) 1983-02-16
PH21204A (en) 1987-08-19
JPS5931762A (en) 1984-02-20
ZA833206B (en) 1984-01-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301