ES8302731A1 - Procedure for the preparation of new 4'-iodine derivatives of glycosidos antraciclina. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of new 4'-iodine derivatives of glycosidos antraciclina. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8302731A1 ES8302731A1 ES511537A ES511537A ES8302731A1 ES 8302731 A1 ES8302731 A1 ES 8302731A1 ES 511537 A ES511537 A ES 511537A ES 511537 A ES511537 A ES 511537A ES 8302731 A1 ES8302731 A1 ES 8302731A1
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- Spain
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- legally binding
- google translate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Procedure for the obtaining of 4 '' - yododerives of glycosides of antracicline, of formula (I), in which r is hydrogen or hydroxy; compounds that have pharmacological applications to inhibit the growth of tumors such as leukemia p388 or leukemia de gross. It consists of the soft alkaline hydrolytic reaction of the 4 '' - doxi-4 '' - iodo-N-trifluoroacetildaunorrubicina in aqueous dissolution of 0.1n sodium hydroxide. The obtained product is extracted with chloroform, the aqueous solution is adjusted to ph 8.6, and it is challenged again with chloroform, the extracts are dried, concentrated and acidified with 0.1n methanolic hydrogen chloride to crystallize. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES511537A ES511537A0 (en) | 1982-04-20 | 1982-04-20 | "PROCEDURE FOR THE PREPARATION OF NEW 4'-YODODERIVES OF ANTHRACICLINE GLYCOSIDES". |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES511537A ES511537A0 (en) | 1982-04-20 | 1982-04-20 | "PROCEDURE FOR THE PREPARATION OF NEW 4'-YODODERIVES OF ANTHRACICLINE GLYCOSIDES". |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8302731A1 true ES8302731A1 (en) | 1983-02-01 |
ES511537A0 ES511537A0 (en) | 1983-02-01 |
Family
ID=8484022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES511537A Granted ES511537A0 (en) | 1982-04-20 | 1982-04-20 | "PROCEDURE FOR THE PREPARATION OF NEW 4'-YODODERIVES OF ANTHRACICLINE GLYCOSIDES". |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES511537A0 (en) |
-
1982
- 1982-04-20 ES ES511537A patent/ES511537A0/en active Granted
Also Published As
Publication number | Publication date |
---|---|
ES511537A0 (en) | 1983-02-01 |
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Legal Events
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PC1A | Transfer granted |