ES8302731A1 - Procedure for the preparation of new 4'-iodine derivatives of glycosidos antraciclina. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new 4'-iodine derivatives of glycosidos antraciclina. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES8302731A1
ES8302731A1 ES511537A ES511537A ES8302731A1 ES 8302731 A1 ES8302731 A1 ES 8302731A1 ES 511537 A ES511537 A ES 511537A ES 511537 A ES511537 A ES 511537A ES 8302731 A1 ES8302731 A1 ES 8302731A1
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Spain
Prior art keywords
translation
procedure
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511537A
Other languages
Spanish (es)
Other versions
ES511537A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Priority to ES511537A priority Critical patent/ES511537A0/en
Publication of ES8302731A1 publication Critical patent/ES8302731A1/en
Publication of ES511537A0 publication Critical patent/ES511537A0/en
Granted legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Procedure for the obtaining of 4 '' - yododerives of glycosides of antracicline, of formula (I), in which r is hydrogen or hydroxy; compounds that have pharmacological applications to inhibit the growth of tumors such as leukemia p388 or leukemia de gross. It consists of the soft alkaline hydrolytic reaction of the 4 '' - doxi-4 '' - iodo-N-trifluoroacetildaunorrubicina in aqueous dissolution of 0.1n sodium hydroxide. The obtained product is extracted with chloroform, the aqueous solution is adjusted to ph 8.6, and it is challenged again with chloroform, the extracts are dried, concentrated and acidified with 0.1n methanolic hydrogen chloride to crystallize. (Machine-translation by Google Translate, not legally binding)
ES511537A 1982-04-20 1982-04-20 "PROCEDURE FOR THE PREPARATION OF NEW 4'-YODODERIVES OF ANTHRACICLINE GLYCOSIDES". Granted ES511537A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES511537A ES511537A0 (en) 1982-04-20 1982-04-20 "PROCEDURE FOR THE PREPARATION OF NEW 4'-YODODERIVES OF ANTHRACICLINE GLYCOSIDES".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES511537A ES511537A0 (en) 1982-04-20 1982-04-20 "PROCEDURE FOR THE PREPARATION OF NEW 4'-YODODERIVES OF ANTHRACICLINE GLYCOSIDES".

Publications (2)

Publication Number Publication Date
ES8302731A1 true ES8302731A1 (en) 1983-02-01
ES511537A0 ES511537A0 (en) 1983-02-01

Family

ID=8484022

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511537A Granted ES511537A0 (en) 1982-04-20 1982-04-20 "PROCEDURE FOR THE PREPARATION OF NEW 4'-YODODERIVES OF ANTHRACICLINE GLYCOSIDES".

Country Status (1)

Country Link
ES (1) ES511537A0 (en)

Also Published As

Publication number Publication date
ES511537A0 (en) 1983-02-01

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