ES8207547A1 - Procedure for the preparation of 7-d-alpha- (methylene-amino-p-hydroxy-phenylacetamide) -3-methyl-3-cefem-4-carboxylate sodium. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of 7-d-alpha- (methylene-amino-p-hydroxy-phenylacetamide) -3-methyl-3-cefem-4-carboxylate sodium. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES8207547A1
ES8207547A1 ES508105A ES508105A ES8207547A1 ES 8207547 A1 ES8207547 A1 ES 8207547A1 ES 508105 A ES508105 A ES 508105A ES 508105 A ES508105 A ES 508105A ES 8207547 A1 ES8207547 A1 ES 8207547A1
Authority
ES
Spain
Prior art keywords
cefem
methylene
alpha
translation
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508105A
Other languages
Spanish (es)
Other versions
ES508105A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ausonia Farmaceutici SRL
Original Assignee
Ausonia Farmaceutici SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ausonia Farmaceutici SRL filed Critical Ausonia Farmaceutici SRL
Publication of ES508105A0 publication Critical patent/ES508105A0/en
Publication of ES8207547A1 publication Critical patent/ES8207547A1/en
Expired legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procedure for the preparation of 7-d-alpha- (methylene-amino-p-hydroxy-anylacetamide) -3-methyl-3-cefem-4-carboxylate sodium. Cefadroxil is reactioned with sodium hydroxide and formaledehide in aqueous media, precipitating the process obtained with a non-solvent, such as isopropanol. Compound is obtained (I). Antibacteric activation and resistance to enzymatic hydrolysis caused by b-lactaminasis and higher and higher levels higher than time. (Machine-translation by Google Translate, not legally binding)
ES508105A 1980-12-23 1981-12-17 Procedure for the preparation of 7-d-alpha- (methylene-amino-p-hydroxy-phenylacetamide) -3-methyl-3-cefem-4-carboxylate sodium. (Machine-translation by Google Translate, not legally binding) Expired ES8207547A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26914/80A IT1141148B (en) 1980-12-23 1980-12-23 ANTIBACTERIAL COMPOUND, MOTOD FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT

Publications (2)

Publication Number Publication Date
ES508105A0 ES508105A0 (en) 1982-10-01
ES8207547A1 true ES8207547A1 (en) 1982-10-01

Family

ID=11220521

Family Applications (1)

Application Number Title Priority Date Filing Date
ES508105A Expired ES8207547A1 (en) 1980-12-23 1981-12-17 Procedure for the preparation of 7-d-alpha- (methylene-amino-p-hydroxy-phenylacetamide) -3-methyl-3-cefem-4-carboxylate sodium. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
AR (1) AR229039A1 (en)
ES (1) ES8207547A1 (en)
IT (1) IT1141148B (en)
PT (1) PT74187B (en)

Also Published As

Publication number Publication date
AR229039A1 (en) 1983-05-31
PT74187A (en) 1982-01-01
IT8026914A0 (en) 1980-12-23
IT1141148B (en) 1986-10-01
ES508105A0 (en) 1982-10-01
PT74187B (en) 1983-05-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201