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Lasa Laboratorios SA
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Lasa Laboratorios SA
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Application filed by Lasa Laboratorios SAfiledCriticalLasa Laboratorios SA
Priority to ES500577ApriorityCriticalpatent/ES500577A0/en
Publication of ES8201961A1publicationCriticalpatent/ES8201961A1/en
Publication of ES500577A0publicationCriticalpatent/ES500577A0/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
PROCEDURE FOR THE PREPARATION OF CARBAMIC ESTERS OF FORMULA (I), WHERE R1, R2 AND R3 ARE HYDROGEN, METHYL, ETHYL OR PROPYL; R4 IS HYDROGEN OR ETHYL, AND R5 BENCILO, A GROUP OF FORMULA (II) AND OTHERS. A CARBAMIC ESTER WITH FREE ALCOHOLIC FUNCTION, OF FORMULA (III), IS HEATED AT REFLUX IN AN ANHYDROUS ORGANIC ENVIRONMENT, WITH A HALOACIL HALIDE OF FORMULA (IV), WHERE X IS CHLORINE OR BROMINE AND R HYDROGEN, METHYL, ETHYL OR ETHYL. THE HALOALKYL-CARBOXIDERIVATE OBTAINED IS ISOLATED AND TREATED WITH AMMONIA OR WITH A MONO OR DISSTITUTED AMINE, IN ANHYDROUS MEDIUM. THE RESULTING PRODUCT IS EXTRACTED WITH AN ACID AQUEOUS SOLUTION, TREATED WITH ACTIVE CARBON AND ALKALINIZED AT PH 7.8-8. (Machine-translation by Google Translate, not legally binding)
ES500577A1981-03-201981-03-20
PROCEDURE FOR OBTAINING NEW CARBAMIC ESTERS
GrantedES500577A0
(en)
A procedure to obtain 4 (3h) -quinazolinones replaced with an aromatic rest in position 3. (Machine-translation by Google Translate, not legally binding)