ES8201951A1 - Procedimiento para la obtencion de 1-(2-aliloxifenoxi)-3- isopropilamino-2-propanol - Google Patents

Procedimiento para la obtencion de 1-(2-aliloxifenoxi)-3- isopropilamino-2-propanol

Info

Publication number
ES8201951A1
ES8201951A1 ES500403A ES500403A ES8201951A1 ES 8201951 A1 ES8201951 A1 ES 8201951A1 ES 500403 A ES500403 A ES 500403A ES 500403 A ES500403 A ES 500403A ES 8201951 A1 ES8201951 A1 ES 8201951A1
Authority
ES
Spain
Prior art keywords
sterified
hydroxy group
manufacture
unsaturated ether
alyloxyphenoxi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES500403A
Other languages
English (en)
Other versions
ES500403A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES500403A0 publication Critical patent/ES500403A0/es
Publication of ES8201951A1 publication Critical patent/ES8201951A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 1-(2-ALILOXIFENOXI)-3ISOPROPIL-AMINO-2-PROPANOL. CONSISTE EN QUE EN UN COMPUESTO DE FORMULA (I), EN LA QUE UNO DE X1 Y X2 ES UN GRUPO HIDROXI ESTERIFICADO, CAPAZ DE REACCIONAR, Y EL OTRO ES HIDROGENO O GRUPO HIDROXI ESTERIFICADO, LOS GRUPOS X1 Y/O X2 SE DISOCIAN CON FORMACION DE ENLACE DOBLE EN LOS ATOMOS DE CARBONO ADYACENTES. LA REACCION DE DISOCIACION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN UM MEDIO DE REACCION BASICA, EN UN ATMOSFERA DE GAS INERTE, A UNA TEMPRATURA ENTRE 20 Y 150 C.
ES500403A 1980-03-18 1981-03-16 Procedimiento para la obtencion de 1-(2-aliloxifenoxi)-3- isopropilamino-2-propanol Expired ES8201951A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH212280A CH643810A5 (en) 1980-03-18 1980-03-18 Process for the preparation of 1-(2-allyloxyphenoxy)-3-isopropyl- amino-2-propanol

Publications (2)

Publication Number Publication Date
ES500403A0 ES500403A0 (es) 1982-01-16
ES8201951A1 true ES8201951A1 (es) 1982-01-16

Family

ID=4226392

Family Applications (1)

Application Number Title Priority Date Filing Date
ES500403A Expired ES8201951A1 (es) 1980-03-18 1981-03-16 Procedimiento para la obtencion de 1-(2-aliloxifenoxi)-3- isopropilamino-2-propanol

Country Status (5)

Country Link
JP (1) JPS56142248A (es)
AT (1) AT375064B (es)
CH (1) CH643810A5 (es)
ES (1) ES8201951A1 (es)
FI (1) FI810806L (es)

Also Published As

Publication number Publication date
FI810806L (fi) 1981-09-19
ES500403A0 (es) 1982-01-16
JPS56142248A (en) 1981-11-06
ATA122481A (de) 1983-11-15
CH643810A5 (en) 1984-06-29
AT375064B (de) 1984-06-25

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