ES8106719A1 - Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina - Google Patents
Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarinaInfo
- Publication number
- ES8106719A1 ES8106719A1 ES494942A ES494942A ES8106719A1 ES 8106719 A1 ES8106719 A1 ES 8106719A1 ES 494942 A ES494942 A ES 494942A ES 494942 A ES494942 A ES 494942A ES 8106719 A1 ES8106719 A1 ES 8106719A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxycumarine
- ethylbencil
- alpha
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE 3(ALFA-ETILBENCIL)-4-HIDROXICUMARINA, COMUNMENTE CONOCIDA COMO FENPROCUMONE, DE FORMULA (I). COMPRENDE LAS SIGUIENTES FASES: PRIMERA, SE HACE REACCIONAR ORTONITROXIACETOFENONA, DE FORMULA (II), EN SOLUCION ACUOSA DE NAOH O KOH, CON UN HALOGENCARBONATO: XCOOET, EN DONDE X ES HALOGENO, DE PREFERENCIA CL; SEGUNDA, EL PRODUCTO DE LA PRIMERA REACCION, UNA VEZ SEPARADO, SE HACE REACCIONAR, EN UN DISOLVENTE APROTICO ANHIDRO, CON BENZALDEHIDO, EN PRESENCIA DE LITIO DIISOPROPILAMIDA; Y POR ULTIMO, EL PRODUCTO DE LA SEGUNDA REACCION, UNA VEZ SEPARADO, SE HACE REACCIONAR, EN UN DISOLVENTE APROTICO ANHIDRO, CON REACTIVO DE "GRIGNARD"; ETMGX, EN PRESENCIA DE HALOGENURO CUPROSO, EN DONDE X ES HALOGENO, DE PREFERENCIA BR O I. DE USO EN LA TERAPIA HUMANA COMO FLUIDIFICANTE DE LA SANGRE. *FORMULA*
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES494942A ES494942A0 (es) | 1980-09-11 | 1980-09-11 | Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES494942A ES494942A0 (es) | 1980-09-11 | 1980-09-11 | Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8106719A1 true ES8106719A1 (es) | 1981-09-01 |
ES494942A0 ES494942A0 (es) | 1981-09-01 |
Family
ID=8481059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES494942A Granted ES494942A0 (es) | 1980-09-11 | 1980-09-11 | Procedimiento para la preparacion de 3(alfa-etilbencil)-4- hidroxicumarina |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES494942A0 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2048090A1 (es) * | 1992-01-31 | 1994-03-01 | Rovi Lab Farmaceut Sa | Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. |
-
1980
- 1980-09-11 ES ES494942A patent/ES494942A0/es active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2048090A1 (es) * | 1992-01-31 | 1994-03-01 | Rovi Lab Farmaceut Sa | Procedimiento para la obtencion de nuevos antitromboticos derivados de la cumarina. |
Also Published As
Publication number | Publication date |
---|---|
ES494942A0 (es) | 1981-09-01 |
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