ES8105967A1 - A procedure for the preparation of cyclhexadene derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of cyclhexadene derivatives. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES8105967A1
ES8105967A1 ES493541A ES493541A ES8105967A1 ES 8105967 A1 ES8105967 A1 ES 8105967A1 ES 493541 A ES493541 A ES 493541A ES 493541 A ES493541 A ES 493541A ES 8105967 A1 ES8105967 A1 ES 8105967A1
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ES
Spain
Prior art keywords
formula
translation
procedure
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493541A
Other languages
Spanish (es)
Other versions
ES493541A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Priority to ES493541A priority Critical patent/ES493541A0/en
Publication of ES8105967A1 publication Critical patent/ES8105967A1/en
Publication of ES493541A0 publication Critical patent/ES493541A0/en
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDURE FOR THE OBTAINING OF CYCLOHEXADIENE DERIVATIVES FROM FORMULA (I), OF ITS ADDITIONAL SALTS OF ACID AND, EVENTUALLY, OF THE OPTIMALLY ACTIVE ENANTIOMERS, FORMULA IN WHICH ONE OF THE RADICALS R1 AND R4 ARE HYDROGEN HYDROGEN OR METHYL, R2 IS HYDROGEN, METHYL OR ETHYL, AND R3 IS METHYL OR ETHYL. IT IS BASED ON THE REACTION OF A COMPOUND OF FORMULA (II) WITH AN AMINE OF FORMULA R2NHR3, IN WHICH R1, R2, R3 AND R4 ARE THE SAME AS IN FORMULA (I), IN THE PRESENCE OF BOROHIDRIDE, REDUCING AGENT, IN A ORGANIC SOLVENT CONSTITUTED BY A LOWER ALCANOL AND AT A TEMPERATURE BETWEEN -10ºC AND 50 GC. THE RACEMATE OBTAINED CAN BE SOLVED BY KNOWN METHODS AND TRANSFORMED IN THE ACID ADDITION SALT. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THEIR ANALGESIC ACTIVITY. *FORMULA* (Machine-translation by Google Translate, not legally binding)
ES493541A 1980-07-21 1980-07-21 A PROCEDURE FOR THE PREPARATION OF CYCLE-HEXADIENE DERIVATIVES Granted ES493541A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES493541A ES493541A0 (en) 1980-07-21 1980-07-21 A PROCEDURE FOR THE PREPARATION OF CYCLE-HEXADIENE DERIVATIVES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES493541A ES493541A0 (en) 1980-07-21 1980-07-21 A PROCEDURE FOR THE PREPARATION OF CYCLE-HEXADIENE DERIVATIVES

Publications (2)

Publication Number Publication Date
ES8105967A1 true ES8105967A1 (en) 1981-07-01
ES493541A0 ES493541A0 (en) 1981-07-01

Family

ID=8480829

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493541A Granted ES493541A0 (en) 1980-07-21 1980-07-21 A PROCEDURE FOR THE PREPARATION OF CYCLE-HEXADIENE DERIVATIVES

Country Status (1)

Country Link
ES (1) ES493541A0 (en)

Also Published As

Publication number Publication date
ES493541A0 (en) 1981-07-01

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