ES8101597A1 - Un procedimiento para la preparacion de naftalen-2-sulfonatode ester ftalidilico de ampicilina - Google Patents

Un procedimiento para la preparacion de naftalen-2-sulfonatode ester ftalidilico de ampicilina

Info

Publication number
ES8101597A1
ES8101597A1 ES486885A ES486885A ES8101597A1 ES 8101597 A1 ES8101597 A1 ES 8101597A1 ES 486885 A ES486885 A ES 486885A ES 486885 A ES486885 A ES 486885A ES 8101597 A1 ES8101597 A1 ES 8101597A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
penicillin salt
penicillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486885A
Other languages
English (en)
Other versions
ES486885A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES486885A0 publication Critical patent/ES486885A0/es
Publication of ES8101597A1 publication Critical patent/ES8101597A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE NAFTALEN-2-SULFONATO DE ESTER FTALIDILICO DE AMPICILINA. CONSTA DE LAS SIGUIENTES ETAPAS: 1) REACCION DE UN COMPUESTO (I) EN QUE R ES UN GRUPO ACILO ORGANICO, CON UN AGENTE QUE FORME UN IMINOHALURO EN EL ATOMO 6-AMINO. 2) REACCION DEL COMPUESTO RESULTANTE PARA INTRODUCIR UN GRUPO QR1 SOBRE EL ATOMO DE CARBONO DEL IMINO PARA FORMAR UN IMINOETER, IMINOTIOETER O AMDIDINA. 3) REACCION DE UN DERIVADO REACTIVO DE UN ACIDO (II). 4) TRATAMIENTO CON AGUA O ALCOHOL. *FORMULA*
ES486885A 1978-04-01 1979-12-13 Un procedimiento para la preparacion de naftalen-2-sulfonatode ester ftalidilico de ampicilina Expired ES8101597A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1282378 1978-04-01

Publications (2)

Publication Number Publication Date
ES486885A0 ES486885A0 (es) 1980-12-16
ES8101597A1 true ES8101597A1 (es) 1980-12-16

Family

ID=10011795

Family Applications (3)

Application Number Title Priority Date Filing Date
ES479132A Expired ES479132A1 (es) 1978-04-01 1979-03-30 Un procedimiento para la preparacion de naftalen-2-sulfonato de ester ftalidico de ampicilina.
ES486884A Granted ES486884A0 (es) 1978-04-01 1979-12-13 Un procedimiento para la preparacion de naftalen-2-sulfonatode ester ftalidilico de ampicilina
ES486885A Expired ES8101597A1 (es) 1978-04-01 1979-12-13 Un procedimiento para la preparacion de naftalen-2-sulfonatode ester ftalidilico de ampicilina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES479132A Expired ES479132A1 (es) 1978-04-01 1979-03-30 Un procedimiento para la preparacion de naftalen-2-sulfonato de ester ftalidico de ampicilina.
ES486884A Granted ES486884A0 (es) 1978-04-01 1979-12-13 Un procedimiento para la preparacion de naftalen-2-sulfonatode ester ftalidilico de ampicilina

Country Status (13)

Country Link
US (1) US4481209A (es)
EP (1) EP0004740B1 (es)
JP (1) JPS54151998A (es)
AR (3) AR223337A1 (es)
AU (1) AU530812B2 (es)
CA (1) CA1151153A (es)
DE (1) DE2961854D1 (es)
ES (3) ES479132A1 (es)
IL (1) IL56934A (es)
MX (1) MX6288E (es)
NZ (1) NZ189945A (es)
PT (1) PT69394A (es)
ZA (1) ZA791504B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51516B1 (en) * 1980-10-06 1987-01-07 Leo Pharm Prod Ltd 1,1-dioxapenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate napsylate
CA1202617A (en) * 1982-03-19 1986-04-01 Norman B. Jones Bacampicillin napsylate
AR014939A1 (es) 1997-12-22 2001-04-11 Astrazeneca Ab Proceso para purificar una solucion de un ester profarmaco de ampicilina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3180862A (en) * 1962-10-29 1965-04-27 Bristol Myers Co Aryl sulfonic acid salts of alpha-aminobenzylpenicillins
US3534035A (en) * 1968-01-31 1970-10-13 American Home Prod Tetrahydronaphthalene sulfonic acid addition salt of ampicillin and process
GB1241844A (en) * 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
GB1364672A (en) * 1971-06-09 1974-08-29 Beecham Group Ltd Penicillins
ES398825A1 (es) * 1971-08-06 1975-05-16 Pharmedical Sa Lab Procedimiento para la preparacion de alfa-amino-acil peni- cilinas.
US3986388A (en) * 1975-09-05 1976-10-19 International Telephone And Telegraph Corporation Fluid property detection system

Also Published As

Publication number Publication date
IL56934A0 (en) 1979-05-31
ZA791504B (en) 1980-04-30
ES8102574A1 (es) 1981-01-16
MX6288E (es) 1985-03-18
AR224408A1 (es) 1981-11-30
CA1151153A (en) 1983-08-02
AR224409A1 (es) 1981-11-30
EP0004740B1 (en) 1982-01-20
PT69394A (fr) 1979-04-01
ES486885A0 (es) 1980-12-16
EP0004740A2 (en) 1979-10-17
NZ189945A (en) 1981-04-24
IL56934A (en) 1982-09-30
DE2961854D1 (en) 1982-03-04
ES486884A0 (es) 1981-01-16
US4481209A (en) 1984-11-06
AU4556279A (en) 1979-10-18
AU530812B2 (en) 1983-07-28
EP0004740A3 (en) 1979-10-31
ES479132A1 (es) 1980-06-16
AR223337A1 (es) 1981-08-14
JPS54151998A (en) 1979-11-29

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